ECSP088714A - Formas cristalinas de sales de n-{2-tert-butil-1-[(4,4-difluorociclohexil)metil]-lh- bencimidazol-5-il}etanosulfonamida - Google Patents
Formas cristalinas de sales de n-{2-tert-butil-1-[(4,4-difluorociclohexil)metil]-lh- bencimidazol-5-il}etanosulfonamidaInfo
- Publication number
- ECSP088714A ECSP088714A EC2008008714A ECSP088714A ECSP088714A EC SP088714 A ECSP088714 A EC SP088714A EC 2008008714 A EC2008008714 A EC 2008008714A EC SP088714 A ECSP088714 A EC SP088714A EC SP088714 A ECSP088714 A EC SP088714A
- Authority
- EC
- Ecuador
- Prior art keywords
- salt
- acid
- tert
- methyl
- etanosulfonamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Una sal del compuesto N-{2-tert-butil-1-[(4,4-difluorociclohexil)metil]-lH-bencimidazol-5-il}etanosulfonamida, la cual es una sal de ácido etanosulfónico, una sal de ácido sulfúrico, una sal de ácido etano disulfónico, una sal de ácido clorhídrico, una sal de ácido bromhídrico, una sal de ácido fosfórico, una sal de ácido acético, una sal de ácido fumárico, una sal de ácido maleico, una sal de ácido tartárico, una sal de ácido cítrico, una sal de ácido metanosulfónico, o una sal de ácido p-toluenosulfónico de dicho compuesto.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78532606P | 2006-03-23 | 2006-03-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP088714A true ECSP088714A (es) | 2008-10-31 |
Family
ID=38522716
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2008008714A ECSP088714A (es) | 2006-03-23 | 2008-09-03 | Formas cristalinas de sales de n-{2-tert-butil-1-[(4,4-difluorociclohexil)metil]-lh- bencimidazol-5-il}etanosulfonamida |
Country Status (18)
Country | Link |
---|---|
US (2) | US7566788B2 (es) |
EP (1) | EP2001856A4 (es) |
JP (1) | JP2009530373A (es) |
KR (1) | KR20080105098A (es) |
CN (1) | CN101454293A (es) |
AR (1) | AR060065A1 (es) |
AU (1) | AU2007227811A1 (es) |
BR (1) | BRPI0709631A2 (es) |
CA (1) | CA2648829A1 (es) |
EC (1) | ECSP088714A (es) |
IL (1) | IL193671A0 (es) |
MX (1) | MX2008012015A (es) |
NO (1) | NO20084353L (es) |
RU (1) | RU2008136556A (es) |
TW (1) | TW200745049A (es) |
UY (1) | UY30232A1 (es) |
WO (1) | WO2007108754A1 (es) |
ZA (1) | ZA200807598B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0302573D0 (sv) * | 2003-09-26 | 2003-09-26 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
BRPI0515897A (pt) * | 2004-09-24 | 2008-08-12 | Astrazeneca Ab | composto, uso do mesmo, composição farmacêutica, e, método para a terapia de dor em um animal de sangue quente, e para a preparação de um composto |
TW200808769A (en) | 2006-04-18 | 2008-02-16 | Astrazeneca Ab | Therapeutic compounds |
US20110086853A1 (en) * | 2009-10-08 | 2011-04-14 | William Brown | Therapeutic Compounds |
CN101758337B (zh) | 2009-12-03 | 2012-02-15 | 湖南阿斯达生化科技有限公司 | 一种助焊剂用非卤素活性剂 |
GB202019335D0 (en) * | 2020-12-09 | 2021-01-20 | Artelo Biosciences Ltd | Pharmaceutical compositions |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1604908A (en) | 1965-06-24 | 1971-05-15 | Substd benzimidazoles - with anthelmintic,fungicidal activity and some with antiviral and antibacterial activity | |
FR5354M (es) | 1965-09-10 | 1967-09-11 | ||
US5387600A (en) | 1992-07-30 | 1995-02-07 | Fuji Photo Film Co., Ltd. | Treating arteriosclerosis using benzimidazole compositions |
DE4237597A1 (de) | 1992-11-06 | 1994-05-11 | Bayer Ag | Substituierte Benzimidazole |
DE4237557A1 (de) | 1992-11-06 | 1994-05-11 | Bayer Ag | Substituierte Benzimidazole |
DE4237617A1 (de) | 1992-11-06 | 1994-05-11 | Bayer Ag | Verwendung von substituierten Benzimidazolen |
EA002357B1 (ru) | 1995-12-28 | 2002-04-25 | Фудзисава Фармасьютикал Ко., Лтд. | Производные бензимидазола |
US6348032B1 (en) * | 1998-11-23 | 2002-02-19 | Cell Pathways, Inc. | Method of inhibiting neoplastic cells with benzimidazole derivatives |
AU6762400A (en) | 1999-08-12 | 2001-03-13 | Cor Therapeutics, Inc. | Inhibitors of factor xa |
US6720317B1 (en) * | 1999-09-17 | 2004-04-13 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
US6844367B1 (en) * | 1999-09-17 | 2005-01-18 | Millennium Pharmaceuticals, Inc. | Benzamides and related inhibitors of factor Xa |
US6632815B2 (en) * | 1999-09-17 | 2003-10-14 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
HUP0203954A2 (hu) | 1999-09-17 | 2003-03-28 | Millennium Pharmaceuticals, Inc. | Xa faktor inhibitorok |
US7115645B2 (en) * | 2000-01-14 | 2006-10-03 | Schering Aktiengesellschaft | 1,2 diarylbenzimidazoles and their pharmaceutical use |
PT1246808E (pt) | 2000-01-14 | 2011-11-30 | Bayer Schering Pharma Ag | 1,2¿diarilbenzimidazol para o tratamento de doenças associadas a uma activação das micróglias |
ATE311366T1 (de) * | 2000-02-29 | 2005-12-15 | Millennium Pharm Inc | Benzamide und ähnliche inhibitoren vom faktor xa |
AU2001273040A1 (en) | 2000-06-27 | 2002-01-08 | Du Pont Pharmaceuticals Company | Factor xa inhibitors |
WO2002046168A1 (en) | 2000-12-07 | 2002-06-13 | Astrazeneca Ab | Therapeutic benzimidazole compounds |
SE0101387D0 (sv) | 2001-04-20 | 2001-04-20 | Astrazeneca Ab | Novel compounds |
JPWO2002100833A1 (ja) | 2001-06-12 | 2004-09-24 | 住友製薬株式会社 | Rhoキナーゼ阻害剤 |
TW200505902A (en) | 2003-03-20 | 2005-02-16 | Schering Corp | Cannabinoid receptor ligands |
SE0301701D0 (sv) | 2003-06-10 | 2003-06-10 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
SE0301699D0 (sv) | 2003-06-10 | 2003-06-10 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
US20050026968A1 (en) | 2003-07-14 | 2005-02-03 | University Of Tennessee Research Foundation | Heterocyclic amides with anti-tuberculosis activity |
WO2005021547A2 (en) * | 2003-08-28 | 2005-03-10 | Pharmaxis Pty Ltd. | Heterocyclic cannabinoid cb2 receptor antagonists |
SE0302572D0 (sv) | 2003-09-26 | 2003-09-26 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
SE0302571D0 (sv) * | 2003-09-26 | 2003-09-26 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
SE0302573D0 (sv) | 2003-09-26 | 2003-09-26 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
SE0302570D0 (sv) * | 2003-09-26 | 2003-09-26 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
CA2567343A1 (en) | 2004-05-20 | 2005-12-01 | Elan Pharmaceuticals, Inc. | N-cyclic sulfonamido inhibitors of gamma secretase |
US20060135773A1 (en) | 2004-06-17 | 2006-06-22 | Semple Joseph E | Trisubstituted nitrogen modulators of tyrosine phosphatases |
ES2697524T3 (es) | 2004-07-30 | 2019-01-24 | Exelixis Inc | Derivados de pirrol como agentes farmacéuticos |
US20060052421A1 (en) * | 2004-09-09 | 2006-03-09 | Eastman Kodak Company | Conjugation agent |
JP2008514594A (ja) | 2004-09-24 | 2008-05-08 | アストラゼネカ・アクチエボラーグ | ベンゾイミダゾール誘導体及びカンナビノイド受容体リガンドとしてのその使用i |
JP2008514595A (ja) | 2004-09-24 | 2008-05-08 | アストラゼネカ・アクチエボラーグ | 化合物、それを含有する組成物、その製造及びその使用ii |
BRPI0515897A (pt) * | 2004-09-24 | 2008-08-12 | Astrazeneca Ab | composto, uso do mesmo, composição farmacêutica, e, método para a terapia de dor em um animal de sangue quente, e para a preparação de um composto |
JP2008514592A (ja) | 2004-09-24 | 2008-05-08 | アストラゼネカ・アクチエボラーグ | ベンゾイミダゾール誘導体、それらを含有する組成物、それらの製造及びそれらの使用iii |
WO2006033628A1 (en) | 2004-09-24 | 2006-03-30 | Astrazeneca Ab | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof |
JP2008514591A (ja) | 2004-09-24 | 2008-05-08 | アストラゼネカ・アクチエボラーグ | ベンゾイミダゾール誘導体及びカンナビノイド受容体リガンドとしてのその使用 |
JP5053092B2 (ja) | 2004-09-24 | 2012-10-17 | アストラゼネカ・アクチエボラーグ | ベンゾイミダゾール誘導体、それを含む組成物、その製造方法及びその使用i |
JP2008514589A (ja) | 2004-09-24 | 2008-05-08 | アストラゼネカ・アクチエボラーグ | 化合物、それらを含有する組成物、それらの製造及びそれらの使用iiii |
WO2006048754A1 (en) * | 2004-11-02 | 2006-05-11 | Pfizer Japan Inc. | Sulfonyl benzimidazole derivatives |
WO2006078941A2 (en) | 2005-01-20 | 2006-07-27 | Sirtris Pharmaceuticals, Inc. | Novel sirtuin activating compounds and methods of use thereof |
-
2007
- 2007-03-20 TW TW096109540A patent/TW200745049A/zh unknown
- 2007-03-22 RU RU2008136556/04A patent/RU2008136556A/ru not_active Application Discontinuation
- 2007-03-22 AU AU2007227811A patent/AU2007227811A1/en not_active Abandoned
- 2007-03-22 UY UY30232A patent/UY30232A1/es unknown
- 2007-03-22 BR BRPI0709631-3A patent/BRPI0709631A2/pt not_active Application Discontinuation
- 2007-03-22 KR KR1020087023039A patent/KR20080105098A/ko not_active Application Discontinuation
- 2007-03-22 AR ARP070101183A patent/AR060065A1/es unknown
- 2007-03-22 JP JP2009501381A patent/JP2009530373A/ja active Pending
- 2007-03-22 WO PCT/SE2007/000281 patent/WO2007108754A1/en active Application Filing
- 2007-03-22 CA CA002648829A patent/CA2648829A1/en not_active Abandoned
- 2007-03-22 US US11/689,864 patent/US7566788B2/en not_active Expired - Fee Related
- 2007-03-22 EP EP07716083A patent/EP2001856A4/en not_active Withdrawn
- 2007-03-22 MX MX2008012015A patent/MX2008012015A/es not_active Application Discontinuation
- 2007-03-22 CN CNA2007800189539A patent/CN101454293A/zh active Pending
-
2008
- 2008-08-25 IL IL193671A patent/IL193671A0/en unknown
- 2008-09-03 EC EC2008008714A patent/ECSP088714A/es unknown
- 2008-09-03 ZA ZA200807598A patent/ZA200807598B/xx unknown
- 2008-10-16 NO NO20084353A patent/NO20084353L/no not_active Application Discontinuation
-
2009
- 2009-07-23 US US12/508,112 patent/US20100022610A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
IL193671A0 (en) | 2009-05-04 |
JP2009530373A (ja) | 2009-08-27 |
TW200745049A (en) | 2007-12-16 |
RU2008136556A (ru) | 2010-04-27 |
AU2007227811A1 (en) | 2007-09-27 |
BRPI0709631A2 (pt) | 2011-07-19 |
US7566788B2 (en) | 2009-07-28 |
ZA200807598B (en) | 2010-02-24 |
AR060065A1 (es) | 2008-05-21 |
UY30232A1 (es) | 2007-10-31 |
US20100022610A1 (en) | 2010-01-28 |
CN101454293A (zh) | 2009-06-10 |
NO20084353L (no) | 2008-10-16 |
CA2648829A1 (en) | 2007-09-27 |
MX2008012015A (es) | 2008-10-01 |
EP2001856A1 (en) | 2008-12-17 |
WO2007108754A1 (en) | 2007-09-27 |
US20070225346A1 (en) | 2007-09-27 |
EP2001856A4 (en) | 2011-02-16 |
KR20080105098A (ko) | 2008-12-03 |
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