ECSP077268A - Polimorfo ii de rapamicina y los usos de los mismos - Google Patents
Polimorfo ii de rapamicina y los usos de los mismosInfo
- Publication number
- ECSP077268A ECSP077268A EC2007007268A ECSP077268A ECSP077268A EC SP077268 A ECSP077268 A EC SP077268A EC 2007007268 A EC2007007268 A EC 2007007268A EC SP077268 A ECSP077268 A EC SP077268A EC SP077268 A ECSP077268 A EC SP077268A
- Authority
- EC
- Ecuador
- Prior art keywords
- rapamycin polymorph
- same
- polymorph
- rapamycin
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
La presente invención provee la Forma II del polimorfo de rapamicina. Esta invención además provee procesos para preparar la Forma II del polimorfo de rapamicina y las composiciones farmacéuticas que incluyen la Forma II del polimorfo de rapamicina
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60309604P | 2004-08-20 | 2004-08-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP077268A true ECSP077268A (es) | 2007-03-29 |
Family
ID=35431373
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2007007268A ECSP077268A (es) | 2004-08-20 | 2007-02-21 | Polimorfo ii de rapamicina y los usos de los mismos |
Country Status (22)
Country | Link |
---|---|
US (1) | US7282505B2 (es) |
EP (1) | EP1781671A1 (es) |
JP (1) | JP2008510710A (es) |
KR (1) | KR20070051863A (es) |
CN (1) | CN101039948A (es) |
AR (1) | AR050374A1 (es) |
AU (1) | AU2005277407A1 (es) |
BR (1) | BRPI0514407A (es) |
CA (1) | CA2575887A1 (es) |
CR (1) | CR8929A (es) |
EC (1) | ECSP077268A (es) |
GT (1) | GT200500223A (es) |
IL (1) | IL181170A0 (es) |
MX (1) | MX2007002044A (es) |
NO (1) | NO20071050L (es) |
PA (1) | PA8642501A1 (es) |
PE (1) | PE20060649A1 (es) |
RU (1) | RU2007104518A (es) |
SV (1) | SV2006002201A (es) |
TW (1) | TW200608973A (es) |
WO (1) | WO2006023627A1 (es) |
ZA (1) | ZA200701453B (es) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1553940T3 (da) | 2002-07-30 | 2008-06-02 | Wyeth Corp | Patenterale formuleringer indeholdende en rapamycin-hydroxyester |
US7349971B2 (en) * | 2004-02-05 | 2008-03-25 | Scenera Technologies, Llc | System for transmitting data utilizing multiple communication applications simultaneously in response to user request without specifying recipient's communication information |
US8551512B2 (en) * | 2004-03-22 | 2013-10-08 | Advanced Cardiovascular Systems, Inc. | Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS |
US8637070B2 (en) | 2005-02-09 | 2014-01-28 | Santen Pharmaceutical Co., Ltd. | Rapamycin formulations and methods of their use |
US8663639B2 (en) | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
EP2001438A2 (en) | 2006-02-09 | 2008-12-17 | Macusight, Inc. | Stable formulations, and methods of their preparation and use |
ES2563288T3 (es) | 2006-03-23 | 2016-03-14 | Santen Pharmaceutical Co., Ltd | Rapamicina en dosis bajas para el tratamiento de enfermedades relacionadas con la permeabilidad vascular |
MX2009001067A (es) * | 2006-07-25 | 2009-06-17 | Abbott Lab | Formas cristalinas de analogos de rapamicina. |
US7812032B2 (en) | 2006-07-25 | 2010-10-12 | Abbott Laboratories | Crystalline forms of rapamycin analogs |
US7820812B2 (en) | 2006-07-25 | 2010-10-26 | Abbott Laboratories | Methods of manufacturing crystalline forms of rapamycin analogs |
US8486926B2 (en) * | 2006-11-17 | 2013-07-16 | Harbor Therapeutics, Inc. | Steroid tetrol solid state forms |
US8414525B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US20080276935A1 (en) | 2006-11-20 | 2008-11-13 | Lixiao Wang | Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs |
US8414909B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US8414910B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US9700704B2 (en) | 2006-11-20 | 2017-07-11 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
US8998846B2 (en) | 2006-11-20 | 2015-04-07 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
US8425459B2 (en) | 2006-11-20 | 2013-04-23 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent |
US8414526B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids |
US9737640B2 (en) | 2006-11-20 | 2017-08-22 | Lutonix, Inc. | Drug releasing coatings for medical devices |
JP2008305262A (ja) * | 2007-06-08 | 2008-12-18 | Konica Minolta Business Technologies Inc | サーバ及びシンクライアント環境でのプリンタ紹介方法 |
WO2010024898A2 (en) | 2008-08-29 | 2010-03-04 | Lutonix, Inc. | Methods and apparatuses for coating balloon catheters |
PT2365802T (pt) | 2008-11-11 | 2017-11-14 | Univ Texas | Microcápsulas de rapamicina e utilização para o tratamento de cancro |
DE102008060549A1 (de) | 2008-12-04 | 2010-06-10 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung |
US20110275798A1 (en) * | 2009-01-21 | 2011-11-10 | Rakesh Bhaiyyaram Mendhe | Method for Determination of Sirolimus Stability and Process for Preparing Its Stable Form |
US20120231037A1 (en) | 2009-02-02 | 2012-09-13 | Yissum Research Development Companyof the Hebrew U | Crystalline drug-containing coatings |
WO2011049659A2 (en) * | 2009-08-05 | 2011-04-28 | The Government Of United States, As Represented By The Secretary Of The Army | Novel use and method of rapamycin to treat toxic shock |
US9283211B1 (en) | 2009-11-11 | 2016-03-15 | Rapamycin Holdings, Llc | Oral rapamycin preparation and use for stomatitis |
CA2855619A1 (en) | 2011-11-15 | 2013-05-23 | Novartis Ag | Combination of a phosphoinositide 3-kinase inhibitor and a modulator of the janus kinase 2 - signal transducer and activator of transcription 5 pathway |
US20150224190A1 (en) | 2012-07-06 | 2015-08-13 | Mohamed Bentires-Alj | Combination of a phosphoinositide 3-kinase inhibitor and an inhibitor of the IL-8/CXCR interaction |
WO2014160328A1 (en) | 2013-03-13 | 2014-10-02 | The Board Of Regents Of The University Of Texas System | Mtor inhibitors for prevention of intestinal polyp growth |
CN113768881A (zh) | 2013-10-08 | 2021-12-10 | 人工智能治疗公司 | 用于治疗淋巴管平滑肌瘤病的雷帕霉素 |
US9700544B2 (en) | 2013-12-31 | 2017-07-11 | Neal K Vail | Oral rapamycin nanoparticle preparations |
EP3089737B1 (en) | 2013-12-31 | 2021-11-03 | Rapamycin Holdings, LLC | Oral rapamycin nanoparticle preparations and use |
KR20160120739A (ko) * | 2014-02-11 | 2016-10-18 | 램 테라퓨틱스, 인코포레이티드 | 림프관평활근종증의 치료를 위한 라파마이신 |
US10307371B2 (en) | 2014-02-11 | 2019-06-04 | AI Therapeutics, Inc. | Rapamycin for the treatment of lymphangioleiomyomatosis |
HUP1400075A2 (hu) | 2014-02-14 | 2015-08-28 | Druggability Technologies Ip Holdco Jersey Ltd | Sirolimus és származékainak komplexei, elõállítása és gyógyszerészeti kompozíciói |
RU2718583C2 (ru) | 2014-04-04 | 2020-04-08 | ЭйАй ТЕРАПЬЮТИКС, ИНК. | Рапамицин-содержащая композиция, вводимая путем ингаляции для лечения возрастных заболеваний |
WO2016057712A1 (en) | 2014-10-07 | 2016-04-14 | Lam Therapeutics, Inc. | An inhalable rapamycin formulation for the treatment of pulmonary hypertension |
MA40910A (fr) | 2014-11-07 | 2017-09-12 | Civitas Therapeutics Inc | Poudres de rapamycine pour administration pulmonaire |
CN106478663A (zh) * | 2015-08-26 | 2017-03-08 | 博瑞生物医药(苏州)股份有限公司 | 一种依维莫司的干燥方法 |
EP3624863B1 (en) | 2017-05-15 | 2021-04-14 | C.R. Bard, Inc. | Medical device with drug-eluting coating and intermediate layer |
CN109020995A (zh) * | 2017-06-12 | 2018-12-18 | 鲁南制药集团股份有限公司 | 一种替西罗莫司的晶型物 |
JP7262581B2 (ja) | 2018-11-14 | 2023-04-21 | ルトニックス,インコーポレーテッド | 改質されたデバイス表面に薬物溶出コーティングを有する医療用デバイス |
CN113939324A (zh) | 2019-04-08 | 2022-01-14 | 巴德外周血管股份有限公司 | 在经改性装置表面上具有药物洗脱涂层的医疗装置 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA737247B (en) | 1972-09-29 | 1975-04-30 | Ayerst Mckenna & Harrison | Rapamycin and process of preparation |
US3993749A (en) | 1974-04-12 | 1976-11-23 | Ayerst Mckenna And Harrison Ltd. | Rapamycin and process of preparation |
UA41884C2 (uk) | 1993-11-05 | 2001-10-15 | Амерікан Хоум Продактс Корпорейшн | Спосіб відокремлення рапаміцину від кислотних, основних та неполярних нейтральних домішок, присутніх в концентраті екстрактів ферментаційного бульйону або маточних розчинів |
-
2005
- 2005-08-16 AR ARP050103448A patent/AR050374A1/es unknown
- 2005-08-18 CN CNA2005800353638A patent/CN101039948A/zh active Pending
- 2005-08-18 EP EP05788650A patent/EP1781671A1/en not_active Withdrawn
- 2005-08-18 CA CA002575887A patent/CA2575887A1/en not_active Abandoned
- 2005-08-18 RU RU2007104518/04A patent/RU2007104518A/ru not_active Application Discontinuation
- 2005-08-18 GT GT200500223A patent/GT200500223A/es unknown
- 2005-08-18 SV SV2005002201A patent/SV2006002201A/es unknown
- 2005-08-18 PA PA20058642501A patent/PA8642501A1/es unknown
- 2005-08-18 BR BRPI0514407-8A patent/BRPI0514407A/pt not_active IP Right Cessation
- 2005-08-18 AU AU2005277407A patent/AU2005277407A1/en not_active Abandoned
- 2005-08-18 JP JP2007528004A patent/JP2008510710A/ja not_active Withdrawn
- 2005-08-18 MX MX2007002044A patent/MX2007002044A/es unknown
- 2005-08-18 PE PE2005000957A patent/PE20060649A1/es not_active Application Discontinuation
- 2005-08-18 WO PCT/US2005/029364 patent/WO2006023627A1/en active Application Filing
- 2005-08-18 US US11/206,472 patent/US7282505B2/en not_active Expired - Fee Related
- 2005-08-18 KR KR1020077003941A patent/KR20070051863A/ko not_active Application Discontinuation
- 2005-08-18 TW TW094128147A patent/TW200608973A/zh unknown
-
2007
- 2007-02-05 IL IL181170A patent/IL181170A0/en unknown
- 2007-02-15 CR CR8929A patent/CR8929A/es not_active Application Discontinuation
- 2007-02-19 ZA ZA200701453A patent/ZA200701453B/xx unknown
- 2007-02-21 EC EC2007007268A patent/ECSP077268A/es unknown
- 2007-02-23 NO NO20071050A patent/NO20071050L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2575887A1 (en) | 2006-03-02 |
ZA200701453B (en) | 2010-08-25 |
IL181170A0 (en) | 2007-07-04 |
TW200608973A (en) | 2006-03-16 |
EP1781671A1 (en) | 2007-05-09 |
CN101039948A (zh) | 2007-09-19 |
SV2006002201A (es) | 2006-05-09 |
AU2005277407A1 (en) | 2006-03-02 |
BRPI0514407A (pt) | 2008-06-10 |
US7282505B2 (en) | 2007-10-16 |
MX2007002044A (es) | 2007-03-29 |
KR20070051863A (ko) | 2007-05-18 |
PE20060649A1 (es) | 2006-08-10 |
US20060040971A1 (en) | 2006-02-23 |
WO2006023627A8 (en) | 2006-11-30 |
AR050374A1 (es) | 2006-10-18 |
PA8642501A1 (es) | 2006-05-16 |
NO20071050L (no) | 2007-05-15 |
RU2007104518A (ru) | 2008-09-27 |
GT200500223A (es) | 2006-03-09 |
CR8929A (es) | 2007-08-28 |
WO2006023627A1 (en) | 2006-03-02 |
JP2008510710A (ja) | 2008-04-10 |
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