CR8929A - Polimorfo ii de rapamicina y usos del mismo - Google Patents
Polimorfo ii de rapamicina y usos del mismoInfo
- Publication number
- CR8929A CR8929A CR8929A CR8929A CR8929A CR 8929 A CR8929 A CR 8929A CR 8929 A CR8929 A CR 8929A CR 8929 A CR8929 A CR 8929A CR 8929 A CR8929 A CR 8929A
- Authority
- CR
- Costa Rica
- Prior art keywords
- same
- rapamycin
- polymorph
- rapamycin polymorph
- provides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
La presente invencion provee polimorfo forma II de rapamicina; esta invencion provee procedimientos para preparar polimorfomo forma II de rapamicina y composiciones farmaceuticas que incluyen polimorfo forma II de rapamicina.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60309604P | 2004-08-20 | 2004-08-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR8929A true CR8929A (es) | 2007-08-28 |
Family
ID=35431373
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR8929A CR8929A (es) | 2004-08-20 | 2007-02-15 | Polimorfo ii de rapamicina y usos del mismo |
Country Status (22)
Country | Link |
---|---|
US (1) | US7282505B2 (es) |
EP (1) | EP1781671A1 (es) |
JP (1) | JP2008510710A (es) |
KR (1) | KR20070051863A (es) |
CN (1) | CN101039948A (es) |
AR (1) | AR050374A1 (es) |
AU (1) | AU2005277407A1 (es) |
BR (1) | BRPI0514407A (es) |
CA (1) | CA2575887A1 (es) |
CR (1) | CR8929A (es) |
EC (1) | ECSP077268A (es) |
GT (1) | GT200500223A (es) |
IL (1) | IL181170A0 (es) |
MX (1) | MX2007002044A (es) |
NO (1) | NO20071050L (es) |
PA (1) | PA8642501A1 (es) |
PE (1) | PE20060649A1 (es) |
RU (1) | RU2007104518A (es) |
SV (1) | SV2006002201A (es) |
TW (1) | TW200608973A (es) |
WO (1) | WO2006023627A1 (es) |
ZA (1) | ZA200701453B (es) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2344821C2 (ru) * | 2002-07-30 | 2009-01-27 | Уайт | Парентеральные композиции, содержащие гидроксиэфиры рапамицина |
US7349971B2 (en) * | 2004-02-05 | 2008-03-25 | Scenera Technologies, Llc | System for transmitting data utilizing multiple communication applications simultaneously in response to user request without specifying recipient's communication information |
US8551512B2 (en) | 2004-03-22 | 2013-10-08 | Advanced Cardiovascular Systems, Inc. | Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS |
US20060258698A1 (en) | 2005-02-09 | 2006-11-16 | Sreenivasu Mudumba | Liquid formulations for treatment of diseases or conditions |
US8663639B2 (en) | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
US8492400B2 (en) | 2006-02-09 | 2013-07-23 | Santen Pharmaceutical Co., Ltd. | Stable formulations, and methods of their preparation and use |
JP5506378B2 (ja) | 2006-03-23 | 2014-05-28 | 参天製薬株式会社 | 血管透過性に関連する疾患または病気のための製剤および方法 |
US7820812B2 (en) | 2006-07-25 | 2010-10-26 | Abbott Laboratories | Methods of manufacturing crystalline forms of rapamycin analogs |
US7812032B2 (en) | 2006-07-25 | 2010-10-12 | Abbott Laboratories | Crystalline forms of rapamycin analogs |
BRPI0714945B8 (pt) * | 2006-07-25 | 2021-05-25 | Abbott Lab | composições de análogo de rapamicina e processos para preparação de formas cristalinas de análogos de rapamicinas |
US8486926B2 (en) * | 2006-11-17 | 2013-07-16 | Harbor Therapeutics, Inc. | Steroid tetrol solid state forms |
US8414525B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US8414526B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids |
US8998846B2 (en) | 2006-11-20 | 2015-04-07 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
US8430055B2 (en) | 2008-08-29 | 2013-04-30 | Lutonix, Inc. | Methods and apparatuses for coating balloon catheters |
US9737640B2 (en) | 2006-11-20 | 2017-08-22 | Lutonix, Inc. | Drug releasing coatings for medical devices |
US20080175887A1 (en) | 2006-11-20 | 2008-07-24 | Lixiao Wang | Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs |
US8425459B2 (en) | 2006-11-20 | 2013-04-23 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent |
US20080276935A1 (en) | 2006-11-20 | 2008-11-13 | Lixiao Wang | Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs |
US9700704B2 (en) | 2006-11-20 | 2017-07-11 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
US8414910B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
JP2008305262A (ja) * | 2007-06-08 | 2008-12-18 | Konica Minolta Business Technologies Inc | サーバ及びシンクライアント環境でのプリンタ紹介方法 |
CN104042612A (zh) | 2008-11-11 | 2014-09-17 | 得克萨斯大学体系董事会 | 哺乳动物雷帕霉素靶蛋白的抑制 |
DE102008060549A1 (de) | 2008-12-04 | 2010-06-10 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung |
US20110275798A1 (en) * | 2009-01-21 | 2011-11-10 | Rakesh Bhaiyyaram Mendhe | Method for Determination of Sirolimus Stability and Process for Preparing Its Stable Form |
WO2010086863A2 (en) | 2009-02-02 | 2010-08-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Crystalline drug-containing coatings |
US20120252834A1 (en) * | 2009-08-05 | 2012-10-04 | The Government Of United States, As Represented By The Secretary Of The Army | Novel use and method of rapamycin to treat toxic shock |
US9283211B1 (en) | 2009-11-11 | 2016-03-15 | Rapamycin Holdings, Llc | Oral rapamycin preparation and use for stomatitis |
RU2014124184A (ru) | 2011-11-15 | 2015-12-27 | Новартис Аг | Комбинация ингибитора фосфоинозитид-3-киназы и модулятора пути янус-киназы 2 - проводника сигнала и активатора транскрипции 5 |
WO2014006115A1 (en) | 2012-07-06 | 2014-01-09 | Novartis Ag | Combination of a phosphoinositide 3-kinase inhibitor and an inhibitor of the il-8/cxcr interaction |
US20160030401A1 (en) | 2013-03-13 | 2016-02-04 | The Board Of Regents Of The University Of Texas System | Use of mtor inhibitors for prevention of intestinal polyp growth and cancer |
EP3054948B1 (en) | 2013-10-08 | 2020-08-12 | AI Therapeutics, Inc. | Rapamycin for the treatment of lymphangioleiomyomatosis |
AU2014373683B2 (en) | 2013-12-31 | 2020-05-07 | Rapamycin Holdings, Llc | Oral rapamycin nanoparticle preparations and use |
US9700544B2 (en) | 2013-12-31 | 2017-07-11 | Neal K Vail | Oral rapamycin nanoparticle preparations |
EP3104891A1 (en) * | 2014-02-11 | 2016-12-21 | Lam Therapeutics, Inc. | Rapamycin for the treatment of lymphangioleiomyomatosis |
US10307371B2 (en) | 2014-02-11 | 2019-06-04 | AI Therapeutics, Inc. | Rapamycin for the treatment of lymphangioleiomyomatosis |
HUP1400075A2 (hu) | 2014-02-14 | 2015-08-28 | Druggability Technologies Ip Holdco Jersey Ltd | Sirolimus és származékainak komplexei, elõállítása és gyógyszerészeti kompozíciói |
BR112016022598A8 (pt) | 2014-04-04 | 2021-06-29 | Ai Therapeutics Inc | composição aerossol farmacêutica na forma de um pó seco para liberação pulmonar, forma de dosagem unitária, pacote farmacêutico, kit e uso |
EP3209330B1 (en) | 2014-10-07 | 2022-02-23 | AI Therapeutics, Inc. | An inhalable sirolimus formulation for the treatment of pulmonary hypertension |
MA40910A (fr) | 2014-11-07 | 2017-09-12 | Civitas Therapeutics Inc | Poudres de rapamycine pour administration pulmonaire |
CN106478663A (zh) * | 2015-08-26 | 2017-03-08 | 博瑞生物医药(苏州)股份有限公司 | 一种依维莫司的干燥方法 |
US20210154372A1 (en) | 2017-05-15 | 2021-05-27 | C.R. Bard, Inc. | Medical device with drug-eluting coating and intermediate layer |
CN109020995A (zh) * | 2017-06-12 | 2018-12-18 | 鲁南制药集团股份有限公司 | 一种替西罗莫司的晶型物 |
JP7262581B2 (ja) | 2018-11-14 | 2023-04-21 | ルトニックス,インコーポレーテッド | 改質されたデバイス表面に薬物溶出コーティングを有する医療用デバイス |
WO2020209828A1 (en) | 2019-04-08 | 2020-10-15 | Bard Peripheral Vascular, Inc. | Medical device with drug-eluting coating on modified device surface |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA737247B (en) | 1972-09-29 | 1975-04-30 | Ayerst Mckenna & Harrison | Rapamycin and process of preparation |
US3993749A (en) | 1974-04-12 | 1976-11-23 | Ayerst Mckenna And Harrison Ltd. | Rapamycin and process of preparation |
UA41884C2 (uk) | 1993-11-05 | 2001-10-15 | Амерікан Хоум Продактс Корпорейшн | Спосіб відокремлення рапаміцину від кислотних, основних та неполярних нейтральних домішок, присутніх в концентраті екстрактів ферментаційного бульйону або маточних розчинів |
-
2005
- 2005-08-16 AR ARP050103448A patent/AR050374A1/es unknown
- 2005-08-18 US US11/206,472 patent/US7282505B2/en not_active Expired - Fee Related
- 2005-08-18 CA CA002575887A patent/CA2575887A1/en not_active Abandoned
- 2005-08-18 PA PA20058642501A patent/PA8642501A1/es unknown
- 2005-08-18 MX MX2007002044A patent/MX2007002044A/es unknown
- 2005-08-18 GT GT200500223A patent/GT200500223A/es unknown
- 2005-08-18 BR BRPI0514407-8A patent/BRPI0514407A/pt not_active IP Right Cessation
- 2005-08-18 RU RU2007104518/04A patent/RU2007104518A/ru not_active Application Discontinuation
- 2005-08-18 EP EP05788650A patent/EP1781671A1/en not_active Withdrawn
- 2005-08-18 JP JP2007528004A patent/JP2008510710A/ja not_active Withdrawn
- 2005-08-18 AU AU2005277407A patent/AU2005277407A1/en not_active Abandoned
- 2005-08-18 WO PCT/US2005/029364 patent/WO2006023627A1/en active Application Filing
- 2005-08-18 TW TW094128147A patent/TW200608973A/zh unknown
- 2005-08-18 KR KR1020077003941A patent/KR20070051863A/ko not_active Application Discontinuation
- 2005-08-18 SV SV2005002201A patent/SV2006002201A/es unknown
- 2005-08-18 PE PE2005000957A patent/PE20060649A1/es not_active Application Discontinuation
- 2005-08-18 CN CNA2005800353638A patent/CN101039948A/zh active Pending
-
2007
- 2007-02-05 IL IL181170A patent/IL181170A0/en unknown
- 2007-02-15 CR CR8929A patent/CR8929A/es not_active Application Discontinuation
- 2007-02-19 ZA ZA200701453A patent/ZA200701453B/xx unknown
- 2007-02-21 EC EC2007007268A patent/ECSP077268A/es unknown
- 2007-02-23 NO NO20071050A patent/NO20071050L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PE20060649A1 (es) | 2006-08-10 |
CA2575887A1 (en) | 2006-03-02 |
TW200608973A (en) | 2006-03-16 |
ECSP077268A (es) | 2007-03-29 |
US7282505B2 (en) | 2007-10-16 |
JP2008510710A (ja) | 2008-04-10 |
BRPI0514407A (pt) | 2008-06-10 |
WO2006023627A8 (en) | 2006-11-30 |
AU2005277407A1 (en) | 2006-03-02 |
RU2007104518A (ru) | 2008-09-27 |
WO2006023627A1 (en) | 2006-03-02 |
US20060040971A1 (en) | 2006-02-23 |
AR050374A1 (es) | 2006-10-18 |
NO20071050L (no) | 2007-05-15 |
IL181170A0 (en) | 2007-07-04 |
KR20070051863A (ko) | 2007-05-18 |
SV2006002201A (es) | 2006-05-09 |
CN101039948A (zh) | 2007-09-19 |
GT200500223A (es) | 2006-03-09 |
ZA200701453B (en) | 2010-08-25 |
EP1781671A1 (en) | 2007-05-09 |
PA8642501A1 (es) | 2006-05-16 |
MX2007002044A (es) | 2007-03-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CR8929A (es) | Polimorfo ii de rapamicina y usos del mismo | |
PA8667201A1 (es) | Nuevos compuestos farmaceuticos | |
HN2008000311A (es) | Formas cristalinas de 4-metil-n-[3-(4-metil-imidazol-1-il)-5-trifluorometil-fenil]-3-(4-piridin-3-il-pirimidin-2-ilamino)-benzamida | |
ATE528989T1 (de) | Kristalline feste rasagilin-base | |
CR10304A (es) | Compuestos de tetrahidropiridotienopirimidina y procedimientos de uso de los mismos | |
PA8693101A1 (es) | Compuestos de isoindol-imida y composiciones que los incluyen y mètodos para su uso | |
CL2011000691A1 (es) | Compuestos derivados de nicotinamida sustituida; composicion farmaceutica que los comprende; uso para el tratamiento y/o prevencion de cancer, infecciones, enfermedades inflamatorias y autoinmunitarias. | |
ECSP10010548A (es) | Composiciones y metodos de preparacion y uso de las mismas | |
TN2009000446A1 (en) | P70 s6 kinase inhibitors | |
ECSP099445A (es) | Quinazolinas para la inhibición de pdk1 | |
UY30369A1 (es) | Compuestos de pirrolo-pirimidina y sus usos | |
CR11427A (es) | 2-fluoro-2 - desoxitetrahidrouridinas como inhibidores de citidina desaminasa | |
CL2012002497A1 (es) | Compuestos derivados de imidazopirimidina,sustituidos, inhibidores de la pde10a; procedimiento de preparacion; composicion farmaceutica; y su uso para el tratamiento o prevencion de trastornos psicoticos, esquizofrenia, enfermedad de parkinson, esclerosis multiple, entre otras. | |
CR10444A (es) | Anticuerpo humanizado de c-kit | |
CR10600A (es) | Ciclopenta (d) pirimidinas hidroxiladas y metoxiladas como inhibidores de akt proteina quinasa | |
ECSP077316A (es) | Compuestos imidazo-3-il-amina bicíclicos sustituidos | |
AR052447A1 (es) | Etansulfonato de 1-(2-metipropil)-1h-imidazo[4,5-c] [1,5] naftiridin-4- amina y metansulfonato de 1-(2- metipropil)-1h-imidazo[4,5 -c] [1,5] naftiridin-4-amina | |
CL2008002295A1 (es) | Compuestos derivados de tiazolida sustituidos con alquilsulfonilos; composicion farmaceutica; y uso para el tratamiento de la hepatitis c. | |
CL2007003100A1 (es) | Compuestos derivados de pirimidina, inhibidores de cisteina proteasa; procesos de preparacion; sales de los compuestos; composicion farmaceutica; y uso para el tratamiento de la malaria. | |
CR9257A (es) | Polimorfo cci-779 y uso del mismo | |
CR9786A (es) | Compuestos de bencimidazol-tiofeno | |
HN2009000018A (es) | Inhibidores de tirosina quinasa | |
ATE530170T1 (de) | Paliperidonformulierung mit verzögerter freisetzung | |
HN2006029142A (es) | Proceso | |
ECSP088691A (es) | Procesos para la síntesis convergente de los derivados de caliqueamicina |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal (granting procedure) |