ECSP066897A - Síntesis de pirrol-2-carbonitrilos - Google Patents
Síntesis de pirrol-2-carbonitrilosInfo
- Publication number
- ECSP066897A ECSP066897A EC2006006897A ECSP066897A ECSP066897A EC SP066897 A ECSP066897 A EC SP066897A EC 2006006897 A EC2006006897 A EC 2006006897A EC SP066897 A ECSP066897 A EC SP066897A EC SP066897 A ECSP066897 A EC SP066897A
- Authority
- EC
- Ecuador
- Prior art keywords
- pyrrole
- solution phase
- carbonitrile
- precipitate
- contacting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Abstract
La presente invención se refiere a procesos para la producción de pirrol-2-carbonitrilos tales como 1-metilpirrol-2-carbonitrilo. Dichos procesos comprenden preferiblemente las etapas de hacer reaccionar un pirrol con isocianato de clorosulfonilo en presencia de un disolvente y poner en contacto el producto resultante con un exceso molar de una amina tal como N,N-dimetilformamida. El producto de esa etapa de puesta en contacto se pone en contacto después con un exceso molar de una base orgánica para producir un precipitado y una fase de solución. El precipitado se separa después a partir de una fase de solución y se aísla el pirrol-2-carbonitrilo correspondiente a partir de la fase de solución resultante.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55780704P | 2004-03-30 | 2004-03-30 | |
US11/086,061 US7399870B2 (en) | 2004-03-30 | 2005-03-22 | Synthesis of pyrrole-2-carbonitriles |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP066897A true ECSP066897A (es) | 2006-11-24 |
Family
ID=34963600
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2006006897A ECSP066897A (es) | 2004-03-30 | 2006-09-29 | Síntesis de pirrol-2-carbonitrilos |
Country Status (22)
Country | Link |
---|---|
US (1) | US7399870B2 (es) |
EP (1) | EP1730109B1 (es) |
JP (2) | JP5068642B2 (es) |
KR (1) | KR20070009654A (es) |
AR (1) | AR049157A1 (es) |
AT (1) | ATE402145T1 (es) |
AU (1) | AU2005230896A1 (es) |
BR (1) | BRPI0509317B1 (es) |
CA (1) | CA2560964C (es) |
CR (1) | CR8641A (es) |
DE (1) | DE602005008408D1 (es) |
DK (1) | DK1730109T3 (es) |
EC (1) | ECSP066897A (es) |
ES (1) | ES2310817T3 (es) |
HN (1) | HN2005000134A (es) |
IL (1) | IL178184A0 (es) |
NO (1) | NO20064891L (es) |
PE (1) | PE20060203A1 (es) |
PL (1) | PL1730109T3 (es) |
RU (1) | RU2006134013A (es) |
TW (1) | TW200604166A (es) |
WO (1) | WO2005097743A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2710293A1 (en) * | 2007-12-20 | 2009-07-02 | Teva Women's Health, Inc. | Dosage regimens and pharmaceutical compositions and packages for emergency contraception |
JP5754768B2 (ja) * | 2011-03-10 | 2015-07-29 | 学校法人明治大学 | 芳香族へテロ環化合物のニトリル化物の製造方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3506642A1 (de) * | 1985-02-26 | 1986-08-28 | A. Nattermann & Cie GmbH, 5000 Köln | Neue pyrrolamidine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
US5204332A (en) * | 1988-12-05 | 1993-04-20 | American Cyanamid Company | Pyrrole carbonitrile and nitropyrrole insecticidal and acaricidal and molluscicidal agents |
KR20000047461A (ko) * | 1998-12-29 | 2000-07-25 | 성재갑 | 트롬빈 억제제 |
-
2005
- 2005-03-22 US US11/086,061 patent/US7399870B2/en not_active Expired - Fee Related
- 2005-03-28 AU AU2005230896A patent/AU2005230896A1/en not_active Withdrawn
- 2005-03-28 BR BRPI0509317-1A patent/BRPI0509317B1/pt not_active IP Right Cessation
- 2005-03-28 DK DK05729200T patent/DK1730109T3/da active
- 2005-03-28 EP EP05729200A patent/EP1730109B1/en active Active
- 2005-03-28 ES ES05729200T patent/ES2310817T3/es active Active
- 2005-03-28 AT AT05729200T patent/ATE402145T1/de not_active IP Right Cessation
- 2005-03-28 WO PCT/US2005/010468 patent/WO2005097743A1/en active Application Filing
- 2005-03-28 KR KR1020067022663A patent/KR20070009654A/ko not_active Application Discontinuation
- 2005-03-28 RU RU2006134013/04A patent/RU2006134013A/ru not_active Application Discontinuation
- 2005-03-28 DE DE602005008408T patent/DE602005008408D1/de active Active
- 2005-03-28 JP JP2007506458A patent/JP5068642B2/ja not_active Expired - Fee Related
- 2005-03-28 CA CA2560964A patent/CA2560964C/en not_active Expired - Fee Related
- 2005-03-28 PL PL05729200T patent/PL1730109T3/pl unknown
- 2005-03-30 PE PE2005000364A patent/PE20060203A1/es not_active Application Discontinuation
- 2005-03-30 AR ARP050101206A patent/AR049157A1/es unknown
- 2005-03-30 HN HN2005000134A patent/HN2005000134A/es unknown
- 2005-03-30 TW TW094109918A patent/TW200604166A/zh unknown
-
2006
- 2006-09-19 IL IL178184A patent/IL178184A0/en unknown
- 2006-09-20 CR CR8641A patent/CR8641A/es not_active Application Discontinuation
- 2006-09-29 EC EC2006006897A patent/ECSP066897A/es unknown
- 2006-10-26 NO NO20064891A patent/NO20064891L/no not_active Application Discontinuation
-
2012
- 2012-04-26 JP JP2012101507A patent/JP2012158599A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2560964C (en) | 2012-10-30 |
RU2006134013A (ru) | 2008-05-10 |
DE602005008408D1 (en) | 2008-09-04 |
US7399870B2 (en) | 2008-07-15 |
EP1730109B1 (en) | 2008-07-23 |
CR8641A (es) | 2007-08-28 |
KR20070009654A (ko) | 2007-01-18 |
PL1730109T3 (pl) | 2008-10-31 |
IL178184A0 (en) | 2006-12-31 |
DK1730109T3 (da) | 2008-09-29 |
PE20060203A1 (es) | 2006-03-30 |
JP2007531748A (ja) | 2007-11-08 |
US20050222432A1 (en) | 2005-10-06 |
BRPI0509317A (pt) | 2007-09-04 |
WO2005097743A1 (en) | 2005-10-20 |
HN2005000134A (es) | 2007-03-26 |
NO20064891L (no) | 2006-10-26 |
JP5068642B2 (ja) | 2012-11-07 |
TW200604166A (en) | 2006-02-01 |
EP1730109A1 (en) | 2006-12-13 |
AR049157A1 (es) | 2006-07-05 |
CA2560964A1 (en) | 2005-10-20 |
AU2005230896A1 (en) | 2005-10-20 |
BRPI0509317B1 (pt) | 2014-04-29 |
JP2012158599A (ja) | 2012-08-23 |
ES2310817T3 (es) | 2009-01-16 |
ATE402145T1 (de) | 2008-08-15 |
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