WO2009030649A3 - Verfahren zur herstellung von teda-derivaten - Google Patents

Verfahren zur herstellung von teda-derivaten Download PDF

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Publication number
WO2009030649A3
WO2009030649A3 PCT/EP2008/061393 EP2008061393W WO2009030649A3 WO 2009030649 A3 WO2009030649 A3 WO 2009030649A3 EP 2008061393 W EP2008061393 W EP 2008061393W WO 2009030649 A3 WO2009030649 A3 WO 2009030649A3
Authority
WO
WIPO (PCT)
Prior art keywords
derivatives
teda
producing
producing teda
relates
Prior art date
Application number
PCT/EP2008/061393
Other languages
English (en)
French (fr)
Other versions
WO2009030649A2 (de
Inventor
Gunther Van Cauwenberge
Johann-Peter Melder
Joachim-Thierry Anders
Christoph Benisch
Rainer Klopsch
Gregor Daun
Christian Dully
Boris Buschhaus
Henning Boeckemeier
Evelyn Pox
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Priority to EP08803391A priority Critical patent/EP2197882A2/de
Priority to CN200880114421A priority patent/CN101842375A/zh
Priority to US12/676,254 priority patent/US20100204438A1/en
Publication of WO2009030649A2 publication Critical patent/WO2009030649A2/de
Publication of WO2009030649A3 publication Critical patent/WO2009030649A3/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung von Triethylendiamin- (TEDA)-Derivaten umfassend die folgenden Schritte: a) Reaktion eines Dihydropyrazins mit einem Olefin, b) gegebenenfalls eine Hydrierung in Anschluss an Schritt a). Weiterhin betrifft die vorliegende Erfindung auch neue TEDA-Derivate als solche sowie deren Verwendung als einbaubare Polyurethan-Katalysatoren.
PCT/EP2008/061393 2007-09-03 2008-08-29 Verfahren zur herstellung von teda-derivaten WO2009030649A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08803391A EP2197882A2 (de) 2007-09-03 2008-08-29 Verfahren zur herstellung von teda-derivaten
CN200880114421A CN101842375A (zh) 2007-09-03 2008-08-29 制备teda衍生物的方法
US12/676,254 US20100204438A1 (en) 2007-09-03 2008-08-29 Method for producing teda derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07115513.9 2007-09-03
EP07115513 2007-09-03

Publications (2)

Publication Number Publication Date
WO2009030649A2 WO2009030649A2 (de) 2009-03-12
WO2009030649A3 true WO2009030649A3 (de) 2009-10-01

Family

ID=40130546

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/061393 WO2009030649A2 (de) 2007-09-03 2008-08-29 Verfahren zur herstellung von teda-derivaten

Country Status (4)

Country Link
US (1) US20100204438A1 (de)
EP (1) EP2197882A2 (de)
CN (1) CN101842375A (de)
WO (1) WO2009030649A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2295438B1 (de) 2008-05-30 2015-03-18 Tosoh Corporation Verfahren zur herstellung einer hydroxyalkyltriethylendiaminverbindung und katalysatorzusammensetzung für die herstellung von polyurethanharz mit der hydroxyalkyltriethylendiaminverbindung
WO2010069856A1 (de) 2008-12-19 2010-06-24 Basf Se Verfahren zur herstellung von reinem triethanolamin (teoa)
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
SG10201707543PA (en) 2013-03-14 2017-11-29 Alkermes Pharma Ireland Ltd Prodrugs of fumarates and their use in treating various deseases
CA2940845C (en) 2014-02-24 2019-09-24 Alkermes Pharma Ireland Limited Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3048031A1 (de) * 1979-12-21 1981-09-17 Firmenich S.A., 1211 Genève Verfahren zur herstellung substituierter pyrazine
WO1998024790A1 (fr) * 1996-12-04 1998-06-11 Synthelabo Derives de benzoate de 1,4-diazabicyclo[2.2.2]oct-2-ylmethyle, leur preparation et leur application en therapeutique
WO2001002404A2 (de) * 1999-07-05 2001-01-11 Performance Chemicals Handels Gmbh Verfahren zur herstellung von triethylendiamin unter einsatz von ethylendiamin
WO2003004499A1 (de) * 2001-07-05 2003-01-16 Basf Aktiengesellschaft Verfahren zur selektiven synthese von triethylendiamin
DE10321565A1 (de) * 2003-05-14 2004-12-02 Symrise Gmbh & Co. Kg Verfahren zur Herstellung von Alkyldihydro-1,4-diazinen und Alkyl-1,4-diazinen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6147185A (en) * 1999-07-23 2000-11-14 Air Products And Chemicals, Inc. 1,4-diazabicyclo[2.2.2]octane compounds and their use for the production of polyurethanes

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3048031A1 (de) * 1979-12-21 1981-09-17 Firmenich S.A., 1211 Genève Verfahren zur herstellung substituierter pyrazine
WO1998024790A1 (fr) * 1996-12-04 1998-06-11 Synthelabo Derives de benzoate de 1,4-diazabicyclo[2.2.2]oct-2-ylmethyle, leur preparation et leur application en therapeutique
WO2001002404A2 (de) * 1999-07-05 2001-01-11 Performance Chemicals Handels Gmbh Verfahren zur herstellung von triethylendiamin unter einsatz von ethylendiamin
WO2003004499A1 (de) * 2001-07-05 2003-01-16 Basf Aktiengesellschaft Verfahren zur selektiven synthese von triethylendiamin
DE10321565A1 (de) * 2003-05-14 2004-12-02 Symrise Gmbh & Co. Kg Verfahren zur Herstellung von Alkyldihydro-1,4-diazinen und Alkyl-1,4-diazinen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TOHRU OISHI: "Synthesis of chiral 2,3-disubstituted 1,4-Diazabicyclo[2.2.2]octane.New ligand for the Osmium-catalyzed Asymmetric Dihydrohylation of Olefins.", TETRAHEDRON LETTERS, vol. 33, no. 5, 1992, NLELSEVIER, AMSTERDAM, pages 639 - 642, XP002512485 *

Also Published As

Publication number Publication date
CN101842375A (zh) 2010-09-22
EP2197882A2 (de) 2010-06-23
WO2009030649A2 (de) 2009-03-12
US20100204438A1 (en) 2010-08-12

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