EA202090751A2 - Новый метод иммунотерапии нескольких видов опухолевых заболеваний крови, таких как острый миелоидный лейкоз (омл) - Google Patents

Новый метод иммунотерапии нескольких видов опухолевых заболеваний крови, таких как острый миелоидный лейкоз (омл)

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EA202090751A2
EA202090751A2 EA202090751A EA202090751A EA202090751A2 EA 202090751 A2 EA202090751 A2 EA 202090751A2 EA 202090751 A EA202090751 A EA 202090751A EA 202090751 A EA202090751 A EA 202090751A EA 202090751 A2 EA202090751 A2 EA 202090751A2
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Prior art keywords
tumor
present
relates
immunotherapy
aml
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EA202090751A
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English (en)
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EA202090751A3 (ru
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Джулиан Стикель
Дэниел Ковалевски
Клаудиа Берлин
Ханс-Георг Раммензее
Стефан Стеванович
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Имматикс Байотекнолоджиз Гмбх
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Publication of EA202090751A2 publication Critical patent/EA202090751A2/ru
Publication of EA202090751A3 publication Critical patent/EA202090751A3/ru

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Abstract

Настоящее изобретение относится к пептидам, нуклеиновым кислотам и клеткам для применения в иммунотерапевтических методах. В частности, настоящее изобретение относится к иммунотерапии рака. Настоящее изобретение относится далее к опухолеассоциированным цитотоксическим пептидным эпитопам Т-клеток (ЦТЛ), в отдельности или в комбинации с другими опухолеассоциированными пептидами, которые служат в качестве активных фармацевтических ингредиентов вакцинных композиций, стимулирующих противоопухолевые иммунные ответы. Настоящее изобретение относится к нескольким новым пептидным последовательностям и их вариантам, образованным из молекул HLA класса I и HLA класса II человеческих опухолевых клеток, которые могут быть использованы в вакцинных композициях для вызывания противоопухолевых иммунных ответов.
EA202090751A 2014-05-09 2015-05-08 Новый метод иммунотерапии нескольких видов опухолевых заболеваний крови, таких как острый миелоидный лейкоз (омл) EA202090751A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1408255.6A GB201408255D0 (en) 2014-05-09 2014-05-09 Novel immunotherapy against several tumours of the blood, such as acute myeloid leukemia (AML)

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EA202090751A2 true EA202090751A2 (ru) 2020-07-31
EA202090751A3 EA202090751A3 (ru) 2020-10-30

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EA201692103A EA035456B1 (ru) 2014-05-09 2015-05-08 Новый метод иммунотерапии нескольких видов опухолевых заболеваний крови, таких как острый миелоидный лейкоз (омл)
EA202090751A EA202090751A3 (ru) 2014-05-09 2015-05-08 Новый метод иммунотерапии нескольких видов опухолевых заболеваний крови, таких как острый миелоидный лейкоз (омл)

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US (2) US10064924B2 (ru)
EP (3) EP3449937A1 (ru)
JP (1) JP6659582B2 (ru)
KR (1) KR20170003976A (ru)
CN (1) CN106459167A (ru)
AU (2) AU2015257652B2 (ru)
BR (1) BR112016025035A2 (ru)
CA (1) CA2946349A1 (ru)
CR (1) CR20160531A (ru)
DK (1) DK3140319T3 (ru)
EA (2) EA035456B1 (ru)
ES (1) ES2747734T3 (ru)
GB (1) GB201408255D0 (ru)
HU (1) HUE045177T2 (ru)
LT (1) LT3140319T (ru)
MA (3) MA49280A (ru)
ME (1) ME03565B (ru)
MX (1) MX2016014711A (ru)
PL (1) PL3140319T3 (ru)
PT (1) PT3140319T (ru)
RS (1) RS59471B1 (ru)
SG (1) SG11201608332SA (ru)
SI (1) SI3140319T1 (ru)
TW (2) TW201920246A (ru)
WO (1) WO2015169945A2 (ru)

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