CY1122083T1 - Καινοτομος ανοσοθεραπεια εναντι ορισμενων ογκων του αιματος, οπως της οξειας μυελογεους λευχαιμιας (ομλ) - Google Patents

Καινοτομος ανοσοθεραπεια εναντι ορισμενων ογκων του αιματος, οπως της οξειας μυελογεους λευχαιμιας (ομλ)

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Publication number
CY1122083T1
CY1122083T1 CY20191101007T CY191101007T CY1122083T1 CY 1122083 T1 CY1122083 T1 CY 1122083T1 CY 20191101007 T CY20191101007 T CY 20191101007T CY 191101007 T CY191101007 T CY 191101007T CY 1122083 T1 CY1122083 T1 CY 1122083T1
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CY
Cyprus
Prior art keywords
present
relates
aml
acute
cells
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CY20191101007T
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English (en)
Inventor
Juliane WALZ
Daniel Kowalewski
Claudia BERLIN
Hans-Georg Rammensee
Stefan Stevanovic
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Immatics Biotechnologies Gmbh
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Publication date
Priority claimed from GBGB1408255.6A external-priority patent/GB201408255D0/en
Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
Publication of CY1122083T1 publication Critical patent/CY1122083T1/el

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    • C12N9/14—Hydrolases (3)
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    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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Abstract

Η παρούσα εφεύρεση σχετίζεται με πεπτίδια, νουκλεϊκά οξέα και κύτταρα για χρήση σε ανοσοθεραπευτικές μεθόδους. Συγκεκριμένα, η παρούσα εφεύρεση σχετίζεται με την ανοσοθεραπεία του καρκίνου. Η παρούσα εφεύρεση σχετίζεται επιπλέον με όγκο-σχετιζόμενους πεπτιδικούς επιτόπους κυτταροτοξικών Τ-κυττάρων (cytotoxic Τ lymphocytes - CTL), μεμονωμένους ή σε συνδυασμό με άλλα ογκο-σχετιζόμενα πεπτίδια, οι οποίοι λειτουργούν ως ενεργά φαρμακευτικά συστατικά συνθέσεων εμβολίων που διεγείρουν αντικαρκινικές ανοσοαπαντήσεις. Η παρούσα εφεύρεση σχετίζεται με αρκετές νέες πεπτιδικές αλληλουχίες και των παραλλαγών τους που προέρχεται από μόρια HLA τάξης I και HLA τάξης II ανθρώπινων καρκινικών κυττάρων που μπορούν να χρησιμοποιηθούν σε συνθέσεις εμβολίων για να επιφέρουν αντικαρκινικές ανοσοαπαντήσεις.
CY20191101007T 2014-05-09 2019-09-24 Καινοτομος ανοσοθεραπεια εναντι ορισμενων ογκων του αιματος, οπως της οξειας μυελογεους λευχαιμιας (ομλ) CY1122083T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461990980P 2014-05-09 2014-05-09
GBGB1408255.6A GB201408255D0 (en) 2014-05-09 2014-05-09 Novel immunotherapy against several tumours of the blood, such as acute myeloid leukemia (AML)
PCT/EP2015/060168 WO2015169945A2 (en) 2014-05-09 2015-05-08 Novel immunotherapy against several tumors of the blood, such as acute myeloid leukemia (aml)

Publications (1)

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CY1122083T1 true CY1122083T1 (el) 2020-11-25

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Country Status (7)

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US (6) US10525115B2 (el)
CY (1) CY1122083T1 (el)
HK (1) HK1232240A1 (el)
HR (1) HRP20191671T1 (el)
IL (2) IL248203A0 (el)
MX (1) MX2019013163A (el)
PH (1) PH12016502008A1 (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
EP4368189A1 (en) * 2022-11-09 2024-05-15 Eberhard Karls Universität Tübingen, Medizinische Fakultät Peptides and combinations of peptides for use in immunotherapy against acute myeloid leukemia (aml) and other hematological neoplasms

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016174A2 (en) 1999-08-30 2001-03-08 Rolf Kiessling Induction of cytotoxic t lymphocyte response by hla class ia restricted epitopes of mycobacterial heat shock protein 65
CA2404260A1 (en) 2000-03-21 2001-09-27 Elitra Pharmaceuticals, Inc. Identification of essential genes in prokaryotes
US7834146B2 (en) 2000-05-08 2010-11-16 Monsanto Technology Llc Recombinant polypeptides associated with plants
KR100692416B1 (ko) 2003-05-26 2007-03-09 학교법인 배재학당 Ｆａｆ1 단편 및 그를 함유하는 종양 전이 억제제
EP1751183A4 (en) 2004-04-29 2008-06-11 Sk Corp FACTOR 1 ASSOCIATED WITH FAS
US7314630B2 (en) 2005-01-07 2008-01-01 Yao-Xiong Hu Compounds and methods of early diagnosis of cervical cancer and genital condyloma with HPV, CHSP60 tumor suppressor H-Ras, K-Ras and PTEN derived peptides modified
DK1806359T3 (da) 2005-09-05 2010-06-14 Immatics Biotechnologies Gmbh Tumorassocierede peptider, der bindes promiskuøst til Humant Leukocyt-Antigen (HLA) klasse II molekyler
PL2338907T3 (pl) 2007-07-27 2016-03-31 Immatics Biotechnologies Gmbh Nowe immunogenne epitopy do immunoterapii

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Publication number Publication date
US20210008189A1 (en) 2021-01-14
HK1232240A1 (zh) 2018-01-05
US20190275130A1 (en) 2019-09-12
US10813985B2 (en) 2020-10-27
US10925949B2 (en) 2021-02-23
US20210023189A1 (en) 2021-01-28
US10525115B2 (en) 2020-01-07
US20200093905A1 (en) 2020-03-26
US10799571B2 (en) 2020-10-13
HRP20191671T1 (hr) 2019-12-13
US20200268862A1 (en) 2020-08-27
MX2019013163A (es) 2020-02-05
IL248203A0 (en) 2016-11-30
US20200254078A1 (en) 2020-08-13
US10668137B2 (en) 2020-06-02
IL271367A (en) 2020-01-30
PH12016502008A1 (en) 2017-02-06
US10898562B1 (en) 2021-01-26

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