EA201990591A1 - Tcr, специфичные к минорному антигену гистосовместимости (h) ha-1, и их применения - Google Patents

Tcr, специфичные к минорному антигену гистосовместимости (h) ha-1, и их применения

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Publication number
EA201990591A1
EA201990591A1 EA201990591A EA201990591A EA201990591A1 EA 201990591 A1 EA201990591 A1 EA 201990591A1 EA 201990591 A EA201990591 A EA 201990591A EA 201990591 A EA201990591 A EA 201990591A EA 201990591 A1 EA201990591 A1 EA 201990591A1
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EA
Eurasian Patent Office
Prior art keywords
cell
antigen
minoral
historic
compatibility
Prior art date
Application number
EA201990591A
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English (en)
Russian (ru)
Inventor
Мари Бликли
Робсон Досса
Даниель Зоммермайер
Original Assignee
Фред Хатчинсон Кэнсер Рисерч Сентер
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Application filed by Фред Хатчинсон Кэнсер Рисерч Сентер filed Critical Фред Хатчинсон Кэнсер Рисерч Сентер
Publication of EA201990591A1 publication Critical patent/EA201990591A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
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    • A61K40/32—T-cell receptors [TCR]
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    • A61K40/41—Vertebrate antigens
    • A61K40/418—Antigens related to induction of tolerance to non-self
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
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    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae

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EA201990591A 2016-09-23 2017-09-22 Tcr, специфичные к минорному антигену гистосовместимости (h) ha-1, и их применения EA201990591A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662399291P 2016-09-23 2016-09-23
PCT/US2017/053112 WO2018058002A1 (en) 2016-09-23 2017-09-22 Tcrs specific for minor histocompatibility (h) antigen ha-1 and uses thereof

Publications (1)

Publication Number Publication Date
EA201990591A1 true EA201990591A1 (ru) 2019-08-30

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EA201990591A EA201990591A1 (ru) 2016-09-23 2017-09-22 Tcr, специфичные к минорному антигену гистосовместимости (h) ha-1, и их применения

Country Status (12)

Country Link
US (3) US10538574B2 (https=)
EP (1) EP3516044B1 (https=)
JP (2) JP6866475B2 (https=)
KR (1) KR102397771B1 (https=)
CN (1) CN109996868A (https=)
AU (2) AU2017331362B2 (https=)
BR (1) BR112019005633A8 (https=)
CA (1) CA3035075A1 (https=)
EA (1) EA201990591A1 (https=)
IL (2) IL265449B (https=)
MX (1) MX2019003176A (https=)
WO (1) WO2018058002A1 (https=)

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