PH12020500095A1 - Improved dual specific polypeptide molecule - Google Patents

Improved dual specific polypeptide molecule

Info

Publication number
PH12020500095A1
PH12020500095A1 PH12020500095A PH12020500095A PH12020500095A1 PH 12020500095 A1 PH12020500095 A1 PH 12020500095A1 PH 12020500095 A PH12020500095 A PH 12020500095A PH 12020500095 A PH12020500095 A PH 12020500095A PH 12020500095 A1 PH12020500095 A1 PH 12020500095A1
Authority
PH
Philippines
Prior art keywords
polypeptide molecule
specific polypeptide
dual specific
improved dual
region derived
Prior art date
Application number
PH12020500095A
Inventor
Martin Hofmann
Felix Unverdorben
Sebastian Bunk
Dominik Maurer
Original Assignee
Immatics Biotechnologies Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102017115966.5A external-priority patent/DE102017115966A1/en
Priority claimed from PCT/EP2018/069157 external-priority patent/WO2019012141A1/en
Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
Publication of PH12020500095A1 publication Critical patent/PH12020500095A1/en

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  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention relates to a bispecific polypeptide molecule comprising a first polypeptide chain and a second polypeptide chain providing a binding region derived from a T cell receptor (TCR) being specific for a major histocompatibility complex (MHC)-associated viral peptide epitope, and a binding region derived from an antibody capable of recruiting human immune effector cells by specifically binding to a surface antigen of said cells, as well as methods of making the bispecific polypeptide molecule, and uses thereof.
PH12020500095A 2017-07-14 2020-01-14 Improved dual specific polypeptide molecule PH12020500095A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201762532713P 2017-07-14 2017-07-14
DE102017115966.5A DE102017115966A1 (en) 2017-07-14 2017-07-14 Polypeptide molecule with improved dual specificity
DE102017119866 2017-08-30
US201862658318P 2018-04-16 2018-04-16
DE102018108995 2018-04-16
PCT/EP2018/069157 WO2019012141A1 (en) 2017-07-14 2018-07-13 Improved dual specificity polypeptide molecule

Publications (1)

Publication Number Publication Date
PH12020500095A1 true PH12020500095A1 (en) 2020-12-07

Family

ID=70848164

Family Applications (2)

Application Number Title Priority Date Filing Date
PH12020500095A PH12020500095A1 (en) 2017-07-14 2020-01-14 Improved dual specific polypeptide molecule
PH12020500098A PH12020500098A1 (en) 2017-07-14 2020-01-14 Improved dual specific polypeptide molecule

Family Applications After (1)

Application Number Title Priority Date Filing Date
PH12020500098A PH12020500098A1 (en) 2017-07-14 2020-01-14 Improved dual specific polypeptide molecule

Country Status (6)

Country Link
JP (1) JP2021019626A (en)
CL (2) CL2020000098A1 (en)
HR (1) HRP20210759T1 (en)
IL (2) IL272046A (en)
PH (2) PH12020500095A1 (en)
ZA (1) ZA202000636B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2968520T1 (en) * 2013-03-14 2022-01-31 Macrogenics, Inc. Bispecific molecules that are immunoreactive with immune effector cells that express an activating receptor

Also Published As

Publication number Publication date
JP2021019626A (en) 2021-02-18
IL272045A (en) 2020-03-31
ZA202000636B (en) 2021-07-28
IL272046A (en) 2020-03-31
CL2020000098A1 (en) 2020-05-29
CL2020000097A1 (en) 2020-05-29
HRP20210759T1 (en) 2021-06-11
PH12020500098A1 (en) 2020-12-07

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