EA201892341A1 - Полиморфные формы 3-[2-бутил-1-(2-диэтиламиноэтил)-1h-бензоимидазол-5-ил]-n-гидроксиакриламида и их применение - Google Patents

Полиморфные формы 3-[2-бутил-1-(2-диэтиламиноэтил)-1h-бензоимидазол-5-ил]-n-гидроксиакриламида и их применение

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Publication number
EA201892341A1
EA201892341A1 EA201892341A EA201892341A EA201892341A1 EA 201892341 A1 EA201892341 A1 EA 201892341A1 EA 201892341 A EA201892341 A EA 201892341A EA 201892341 A EA201892341 A EA 201892341A EA 201892341 A1 EA201892341 A1 EA 201892341A1
Authority
EA
Eurasian Patent Office
Prior art keywords
hydroxyacrylamide
benzoimidazol
diethylaminoethyl
butyl
application
Prior art date
Application number
EA201892341A
Other languages
English (en)
Russian (ru)
Inventor
Дэвид Дункан
Original Assignee
Мей Фарма, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мей Фарма, Инк. filed Critical Мей Фарма, Инк.
Publication of EA201892341A1 publication Critical patent/EA201892341A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA201892341A 2016-05-02 2017-05-01 Полиморфные формы 3-[2-бутил-1-(2-диэтиламиноэтил)-1h-бензоимидазол-5-ил]-n-гидроксиакриламида и их применение EA201892341A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662330673P 2016-05-02 2016-05-02
PCT/US2017/030414 WO2017192451A1 (en) 2016-05-02 2017-05-01 Polymorphic forms of 3-[2-butyl-1-(2-diethylamino-ehtyl)-1h-benzoimidazol-5-yl]-n-hydroxy-acrylamide and uses thereof

Publications (1)

Publication Number Publication Date
EA201892341A1 true EA201892341A1 (ru) 2019-05-31

Family

ID=60203321

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201892341A EA201892341A1 (ru) 2016-05-02 2017-05-01 Полиморфные формы 3-[2-бутил-1-(2-диэтиламиноэтил)-1h-бензоимидазол-5-ил]-n-гидроксиакриламида и их применение

Country Status (20)

Country Link
US (2) US10626092B2 (enExample)
EP (2) EP3939966A1 (enExample)
JP (1) JP2019514905A (enExample)
KR (1) KR20190005904A (enExample)
CN (1) CN109414425A (enExample)
AR (1) AR108257A1 (enExample)
AU (1) AU2017261218A1 (enExample)
BR (1) BR112018072439A2 (enExample)
CA (1) CA3022011A1 (enExample)
CL (1) CL2018003109A1 (enExample)
CO (1) CO2018012941A2 (enExample)
EA (1) EA201892341A1 (enExample)
ES (1) ES2886495T3 (enExample)
IL (1) IL262578A (enExample)
MA (1) MA44880A (enExample)
MX (1) MX382095B (enExample)
PH (1) PH12018502296B1 (enExample)
SG (1) SG11201809471UA (enExample)
TW (1) TW201741286A (enExample)
WO (1) WO2017192451A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110291071B (zh) * 2017-02-28 2022-04-26 苏州科睿思制药有限公司 Sb-939的盐的晶型及其制备方法和用途
WO2019126282A1 (en) 2017-12-19 2019-06-27 Assia Chemical Industries Ltd. Crystalline polymorphs of pracinostat and pracinostat salts
WO2019149262A1 (zh) * 2018-02-05 2019-08-08 苏州科睿思制药有限公司 Sb-939的晶型及其制备方法和用途
WO2021217180A1 (en) * 2020-04-22 2021-10-28 Johnson Matthey Public Limited Company Novel forms of pracinostat dihydrochloride

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Also Published As

Publication number Publication date
PH12018502296A1 (en) 2019-07-08
CN109414425A (zh) 2019-03-01
CO2018012941A2 (es) 2018-12-28
AR108257A1 (es) 2018-08-01
US20200317621A1 (en) 2020-10-08
MA44880A (fr) 2021-03-17
TW201741286A (zh) 2017-12-01
CA3022011A1 (en) 2017-11-09
JP2019514905A (ja) 2019-06-06
US10626092B2 (en) 2020-04-21
SG11201809471UA (en) 2018-11-29
EP3452035B1 (en) 2021-07-07
EP3939966A1 (en) 2022-01-19
PH12018502296B1 (en) 2022-04-06
MX382095B (es) 2025-03-13
KR20190005904A (ko) 2019-01-16
BR112018072439A2 (pt) 2019-02-19
WO2017192451A1 (en) 2017-11-09
MX2018013349A (es) 2019-02-20
ES2886495T3 (es) 2021-12-20
US20190152923A1 (en) 2019-05-23
IL262578A (en) 2018-12-31
EP3452035A1 (en) 2019-03-13
EP3452035A4 (en) 2019-09-25
AU2017261218A1 (en) 2018-11-29
CL2018003109A1 (es) 2019-04-26

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