MX2018013349A - Formas polimorficas de 3-[2-butil-1-(2-dietilamino-etil-1h-benzoim idazol-5-yl]-n-hidroxi-acrilamida y sus usos. - Google Patents

Formas polimorficas de 3-[2-butil-1-(2-dietilamino-etil-1h-benzoim idazol-5-yl]-n-hidroxi-acrilamida y sus usos.

Info

Publication number
MX2018013349A
MX2018013349A MX2018013349A MX2018013349A MX2018013349A MX 2018013349 A MX2018013349 A MX 2018013349A MX 2018013349 A MX2018013349 A MX 2018013349A MX 2018013349 A MX2018013349 A MX 2018013349A MX 2018013349 A MX2018013349 A MX 2018013349A
Authority
MX
Mexico
Prior art keywords
diethylamino
acrylamide
butyl
ehtyl
hydroxy
Prior art date
Application number
MX2018013349A
Other languages
English (en)
Inventor
Duncan David
Original Assignee
Mei Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mei Pharma Inc filed Critical Mei Pharma Inc
Publication of MX2018013349A publication Critical patent/MX2018013349A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14Radicals substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08Radicals containing only hydrogen and carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Abstract

Se describen Polimorfos de Formas cristalinas del 3-[2-butil-1-(2-dietilamino-etil)-1H-benzoimidazol-5-il]-N-hidrox i-acrilamida. También se presentan composiciones farmacéuticas y los usos de las mismas, Formas compuestas y composiciones, para el tratamiento de enfermedades y afecciones.
MX2018013349A 2016-05-02 2017-05-01 Formas polimorficas de 3-[2-butil-1-(2-dietilamino-etil-1h-benzoim idazol-5-yl]-n-hidroxi-acrilamida y sus usos. MX2018013349A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662330673P 2016-05-02 2016-05-02
PCT/US2017/030414 WO2017192451A1 (en) 2016-05-02 2017-05-01 Polymorphic forms of 3-[2-butyl-1-(2-diethylamino-ehtyl)-1h-benzoimidazol-5-yl]-n-hydroxy-acrylamide and uses thereof

Publications (1)

Publication Number Publication Date
MX2018013349A true MX2018013349A (es) 2019-02-20

Family

ID=60203321

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018013349A MX2018013349A (es) 2016-05-02 2017-05-01 Formas polimorficas de 3-[2-butil-1-(2-dietilamino-etil-1h-benzoim idazol-5-yl]-n-hidroxi-acrilamida y sus usos.

Country Status (20)

Country Link
US (2) US10626092B2 (es)
EP (2) EP3939966A1 (es)
JP (1) JP2019514905A (es)
KR (1) KR20190005904A (es)
CN (1) CN109414425A (es)
AR (1) AR108257A1 (es)
AU (1) AU2017261218A1 (es)
BR (1) BR112018072439A2 (es)
CA (1) CA3022011A1 (es)
CL (1) CL2018003109A1 (es)
CO (1) CO2018012941A2 (es)
EA (1) EA201892341A1 (es)
ES (1) ES2886495T3 (es)
IL (1) IL262578A (es)
MA (1) MA44880A (es)
MX (1) MX2018013349A (es)
PH (1) PH12018502296A1 (es)
SG (1) SG11201809471UA (es)
TW (1) TW201741286A (es)
WO (1) WO2017192451A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018157742A1 (zh) * 2017-02-28 2018-09-07 苏州科睿思制药有限公司 Sb-939的盐的晶型及其制备方法和用途
WO2019126282A1 (en) 2017-12-19 2019-06-27 Assia Chemical Industries Ltd. Crystalline polymorphs of pracinostat and pracinostat salts
WO2019149262A1 (zh) * 2018-02-05 2019-08-08 苏州科睿思制药有限公司 Sb-939的晶型及其制备方法和用途
WO2021217180A1 (en) 2020-04-22 2021-10-28 Johnson Matthey Public Limited Company Novel forms of pracinostat dihydrochloride

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Also Published As

Publication number Publication date
MA44880A (fr) 2021-03-17
EP3939966A1 (en) 2022-01-19
BR112018072439A2 (pt) 2019-02-19
SG11201809471UA (en) 2018-11-29
PH12018502296B1 (en) 2019-07-08
WO2017192451A1 (en) 2017-11-09
PH12018502296A1 (en) 2019-07-08
JP2019514905A (ja) 2019-06-06
US10626092B2 (en) 2020-04-21
CO2018012941A2 (es) 2018-12-28
AU2017261218A1 (en) 2018-11-29
KR20190005904A (ko) 2019-01-16
AR108257A1 (es) 2018-08-01
US20200317621A1 (en) 2020-10-08
EP3452035A4 (en) 2019-09-25
IL262578A (en) 2018-12-31
EA201892341A1 (ru) 2019-05-31
ES2886495T3 (es) 2021-12-20
US20190152923A1 (en) 2019-05-23
CL2018003109A1 (es) 2019-04-26
CA3022011A1 (en) 2017-11-09
TW201741286A (zh) 2017-12-01
CN109414425A (zh) 2019-03-01
EP3452035A1 (en) 2019-03-13
EP3452035B1 (en) 2021-07-07

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