EA201792289A1 - Способы обнаружения агглютинации и композиции для их осуществления - Google Patents
Способы обнаружения агглютинации и композиции для их осуществленияInfo
- Publication number
- EA201792289A1 EA201792289A1 EA201792289A EA201792289A EA201792289A1 EA 201792289 A1 EA201792289 A1 EA 201792289A1 EA 201792289 A EA201792289 A EA 201792289A EA 201792289 A EA201792289 A EA 201792289A EA 201792289 A1 EA201792289 A1 EA 201792289A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- methods
- detecting
- antigen
- implementation
- agglutinations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/117—Modifications characterised by incorporating modified base
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/197—Modifications characterised by incorporating a spacer/coupling moiety
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2531/00—Reactions of nucleic acids characterised by
- C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
- C12Q2531/113—PCR
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562149324P | 2015-04-17 | 2015-04-17 | |
| PCT/US2016/027906 WO2016168711A1 (en) | 2015-04-17 | 2016-04-15 | Methods for detecting agglutination and compositions for use in practicing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201792289A1 true EA201792289A1 (ru) | 2018-04-30 |
Family
ID=57127062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201792289A EA201792289A1 (ru) | 2015-04-17 | 2016-04-15 | Способы обнаружения агглютинации и композиции для их осуществления |
Country Status (12)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106591436A (zh) * | 2016-11-24 | 2017-04-26 | 湖南大学 | 用于检测人体内低丰度抗体的邻位连接核酸探针与试剂盒及其制备方法 |
| JP2020515267A (ja) * | 2017-03-30 | 2020-05-28 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 多重アイソタイプ特異的抗体の検出 |
| CN109142730B (zh) * | 2018-06-14 | 2021-04-23 | 郑州大学第一附属医院 | 一种肺癌标志物抗-psip1自身抗体及其应用 |
| DE202020006093U1 (de) * | 2019-05-06 | 2025-04-09 | The Regents Of The University Of California | Nicht-HLA-Marker der Transplantatabstoßung |
| CN111323590B (zh) * | 2020-03-19 | 2022-04-22 | 福建省立医院 | 抗TIF1γ-IgA与抗TIF1γ-IgG作为联合诊断标志物在肺癌诊断中的应用 |
| CN111398584A (zh) * | 2020-03-20 | 2020-07-10 | 北京良芯生物科技发展有限公司 | 一种用于检测人类免疫缺陷病毒hiv1/2抗体的蛋白芯片及其制备方法 |
| CN111499724A (zh) * | 2020-04-15 | 2020-08-07 | 上海领潮生物新材料有限公司 | 一种s-腺苷同型半胱氨酸-鸡卵白蛋白偶联物的制备方法 |
| CN115397464A (zh) * | 2020-04-24 | 2022-11-25 | 美国西门子医学诊断股份有限公司 | 用于使用抗人免疫球蛋白抗体的抗微生物血清学测定的组合物、试剂盒和方法 |
| EP4430215A4 (en) * | 2021-11-08 | 2025-10-22 | Summit Biolabs Inc | DEVICES AND METHODS FOR TESTING STD PATHOGENS WITHOUT NUCLEIC ACID EXTRACTION |
| CN114316016B (zh) * | 2021-12-14 | 2023-11-10 | 江苏浩欧博生物医药股份有限公司 | 一种Jo-1抗原生物素化的方法及抗Jo-1抗体检测试剂盒 |
| CN115060912B (zh) * | 2022-06-23 | 2024-02-02 | 南京浦光生物科技有限公司 | 检测目标抗体的试剂组合、试剂盒、检测系统及检测方法 |
| EP4389913A1 (en) * | 2022-12-23 | 2024-06-26 | Universität Heidelberg | A pcr-elisa analogous antibody-free method for detecting a target nucleic acid in a sample |
| CN116125076A (zh) * | 2022-12-30 | 2023-05-16 | 广州医科大学 | 检测桥粒蛋白的试剂在制备肝纤维化的检测产品中的应用 |
| CN118667920B (zh) * | 2024-07-30 | 2024-11-12 | 北京华诺奥美基因生物科技有限公司 | 一种基于微流控的低丰度生物标志物的检测试剂盒、检测方法及其应用 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4292403A (en) | 1978-08-24 | 1981-09-29 | Akzona Incorporated | Detection and/or determination of IgM, IgA, IgD and IgE immunoglobulins |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4883867A (en) | 1985-11-01 | 1989-11-28 | Becton, Dickinson And Company | Detection of reticulocytes, RNA or DNA |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| EP0540693B1 (en) * | 1990-07-24 | 1999-01-20 | F. Hoffmann-La Roche Ag | THE REDUCTION OF NON-SPECIFIC AMPLIFICATION DURING $i(IN VITRO) NUCLEIC ACID AMPLIFICATION USING MODIFIED NUCLEIC ACID BASES |
| EP0605655B1 (en) | 1991-09-16 | 1997-05-07 | Molecular Probes, Inc. | Dimers of unsymmetrical cyanine dyes |
| US5321130A (en) | 1992-02-10 | 1994-06-14 | Molecular Probes, Inc. | Unsymmetrical cyanine dyes with a cationic side chain |
| CA2145278C (en) | 1992-09-25 | 2009-03-10 | Commonwealth Scientific And Industrial Research Organisation | Target binding polypeptide |
| US5410030A (en) | 1993-04-05 | 1995-04-25 | Molecular Probes, Inc. | Dimers of unsymmetrical cyanine dyes containing pyridinium moieties |
| US5436134A (en) | 1993-04-13 | 1995-07-25 | Molecular Probes, Inc. | Cyclic-substituted unsymmetrical cyanine dyes |
| US5658751A (en) | 1993-04-13 | 1997-08-19 | Molecular Probes, Inc. | Substituted unsymmetrical cyanine dyes with selected permeability |
| US5512462A (en) | 1994-02-25 | 1996-04-30 | Hoffmann-La Roche Inc. | Methods and reagents for the polymerase chain reaction amplification of long DNA sequences |
| US20030104361A1 (en) | 1997-09-29 | 2003-06-05 | Susan Weininger | Method of detection of nucleic acids with a specific sequence composition |
| AUPO591797A0 (en) | 1997-03-27 | 1997-04-24 | Commonwealth Scientific And Industrial Research Organisation | High avidity polyvalent and polyspecific reagents |
| SE504798C2 (sv) * | 1995-06-16 | 1997-04-28 | Ulf Landegren | Immunanalys och testkit med två reagens som kan tvärbindas om de adsorberats till analyten |
| EP1006197A1 (en) * | 1998-12-04 | 2000-06-07 | Transgene S.A. | Use of an immuno complex for the preparation of a therapeutic composition useful for transfecting a polynucleotide into macropinocyte cells |
| SE516272C2 (sv) | 2000-02-18 | 2001-12-10 | Ulf Landegren | Metoder och kit för analytdetektion mha proximitets-probning |
| US6511809B2 (en) * | 2000-06-13 | 2003-01-28 | E. I. Du Pont De Nemours And Company | Method for the detection of an analyte by means of a nucleic acid reporter |
| US8013134B2 (en) * | 2001-11-23 | 2011-09-06 | Olink Ab | Kit for proximity probing with multivalent proximity probes |
| US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| TWI375796B (en) | 2003-04-18 | 2012-11-01 | Becton Dickinson Co | Immuno-amplification |
| US7198900B2 (en) | 2003-08-29 | 2007-04-03 | Applera Corporation | Multiplex detection compositions, methods, and kits |
| WO2005074417A2 (en) * | 2003-09-03 | 2005-08-18 | Salk Institute For Biological Studies | Multiple antigen detection assays and reagents |
| WO2005045439A1 (en) * | 2003-11-07 | 2005-05-19 | Hepgenics Pty Ltd | Binding assay components |
| WO2005123963A2 (en) * | 2004-06-14 | 2005-12-29 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for use in analyte detection using proximity probes |
| CN101137758B (zh) * | 2004-11-03 | 2012-10-10 | 意力速分子诊断股份有限公司 | 均相分析物检测 |
| US8673567B2 (en) | 2006-03-08 | 2014-03-18 | Atila Biosystems, Inc. | Method and kit for nucleic acid sequence detection |
| US20070281367A1 (en) * | 2006-05-03 | 2007-12-06 | Applera Corporation | Methods, Compositions, and Kits for Quantitating Antibodies |
| WO2008066483A1 (en) * | 2006-11-27 | 2008-06-05 | Mohammad Alimohammadi | Use of nalp5 in methods for diagnosis and therapy of parathyroid related disorders |
| JP2010226986A (ja) * | 2009-03-26 | 2010-10-14 | Kaneka Corp | 抗原または抗体の検出方法 |
| US20120277113A1 (en) * | 2009-11-18 | 2012-11-01 | Ruo-Pan Huang | Array-based proximity ligation association assays |
| US8993347B2 (en) * | 2009-12-17 | 2015-03-31 | Cornell University | Methods for detecting antibodies in mucosal samples and device for sampling mucosal material |
| GB201108678D0 (en) | 2011-05-24 | 2011-07-06 | Olink Ab | Multiplexed proximity ligation assay |
| US9823248B2 (en) * | 2011-11-15 | 2017-11-21 | Erasmus University Medical Center Rotterdam | Methods and kits for detecting IgE-expressing B cells |
-
2016
- 2016-04-15 AU AU2016249392A patent/AU2016249392A1/en not_active Abandoned
- 2016-04-15 BR BR112017022329A patent/BR112017022329A2/pt not_active IP Right Cessation
- 2016-04-15 JP JP2017554311A patent/JP6822973B2/ja active Active
- 2016-04-15 WO PCT/US2016/027906 patent/WO2016168711A1/en not_active Ceased
- 2016-04-15 EA EA201792289A patent/EA201792289A1/ru unknown
- 2016-04-15 US US15/566,594 patent/US11149296B2/en active Active
- 2016-04-15 EP EP22177391.4A patent/EP4123031B1/en active Active
- 2016-04-15 EP EP16780915.1A patent/EP3283638B1/en active Active
- 2016-04-15 FI FIEP22177391.4T patent/FI4123031T3/fi active
- 2016-04-15 CA CA2982998A patent/CA2982998A1/en not_active Abandoned
- 2016-04-15 CN CN201680031621.3A patent/CN107614699A/zh active Pending
- 2016-04-15 ES ES22177391T patent/ES3073950T3/es active Active
-
2017
- 2017-10-19 ZA ZA2017/07114A patent/ZA201707114B/en unknown
-
2021
- 2021-09-14 US US17/474,424 patent/US12054768B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2016249392A1 (en) | 2017-11-16 |
| EP3283638B1 (en) | 2022-06-08 |
| CN107614699A (zh) | 2018-01-19 |
| EP3283638A1 (en) | 2018-02-21 |
| US20180100181A1 (en) | 2018-04-12 |
| US20210403978A1 (en) | 2021-12-30 |
| JP2018512862A (ja) | 2018-05-24 |
| EP4123031A1 (en) | 2023-01-25 |
| US11149296B2 (en) | 2021-10-19 |
| ZA201707114B (en) | 2019-02-27 |
| US12054768B2 (en) | 2024-08-06 |
| JP6822973B2 (ja) | 2021-01-27 |
| ES3073950T3 (en) | 2026-07-16 |
| FI4123031T3 (fi) | 2026-07-13 |
| WO2016168711A1 (en) | 2016-10-20 |
| BR112017022329A2 (pt) | 2018-07-17 |
| EP4123031B1 (en) | 2026-06-03 |
| CA2982998A1 (en) | 2016-10-20 |
| EP3283638A4 (en) | 2018-09-12 |
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