FI4123031T3 - Menetelmät agglutinaation tunnistamiseksi ja niiden toteuttamiseen käytettäviä koostumuksia - Google Patents

Menetelmät agglutinaation tunnistamiseksi ja niiden toteuttamiseen käytettäviä koostumuksia

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Publication number
FI4123031T3
FI4123031T3 FIEP22177391.4T FI22177391T FI4123031T3 FI 4123031 T3 FI4123031 T3 FI 4123031T3 FI 22177391 T FI22177391 T FI 22177391T FI 4123031 T3 FI4123031 T3 FI 4123031T3
Authority
FI
Finland
Prior art keywords
polynucleotide
antigen
antibody
sample
amplification
Prior art date
Application number
FIEP22177391.4T
Other languages
English (en)
Finnish (fi)
Inventor
Peter Robinson
Cheng-Ting Tsai
Carolyn Bertozzi
Original Assignee
Univ California
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Publication date
Application filed by Univ California filed Critical Univ California
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Publication of FI4123031T3 publication Critical patent/FI4123031T3/fi

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/117—Modifications characterised by incorporating modified base
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/155—Modifications characterised by incorporating/generating a new priming site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/197—Modifications characterised by incorporating a spacer/coupling moiety
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FIEP22177391.4T 2015-04-17 2016-04-15 Menetelmät agglutinaation tunnistamiseksi ja niiden toteuttamiseen käytettäviä koostumuksia FI4123031T3 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562149324P 2015-04-17 2015-04-17

Publications (1)

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FI4123031T3 true FI4123031T3 (fi) 2026-07-13

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Country Status (12)

Country Link
US (2) US11149296B2 (cg-RX-API-DMAC10.html)
EP (2) EP4123031B1 (cg-RX-API-DMAC10.html)
JP (1) JP6822973B2 (cg-RX-API-DMAC10.html)
CN (1) CN107614699A (cg-RX-API-DMAC10.html)
AU (1) AU2016249392A1 (cg-RX-API-DMAC10.html)
BR (1) BR112017022329A2 (cg-RX-API-DMAC10.html)
CA (1) CA2982998A1 (cg-RX-API-DMAC10.html)
EA (1) EA201792289A1 (cg-RX-API-DMAC10.html)
ES (1) ES3073950T3 (cg-RX-API-DMAC10.html)
FI (1) FI4123031T3 (cg-RX-API-DMAC10.html)
WO (1) WO2016168711A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201707114B (cg-RX-API-DMAC10.html)

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JP2020515267A (ja) * 2017-03-30 2020-05-28 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 多重アイソタイプ特異的抗体の検出
CN109142730B (zh) * 2018-06-14 2021-04-23 郑州大学第一附属医院 一种肺癌标志物抗-psip1自身抗体及其应用
DE202020006093U1 (de) * 2019-05-06 2025-04-09 The Regents Of The University Of California Nicht-HLA-Marker der Transplantatabstoßung
CN111323590B (zh) * 2020-03-19 2022-04-22 福建省立医院 抗TIF1γ-IgA与抗TIF1γ-IgG作为联合诊断标志物在肺癌诊断中的应用
CN111398584A (zh) * 2020-03-20 2020-07-10 北京良芯生物科技发展有限公司 一种用于检测人类免疫缺陷病毒hiv1/2抗体的蛋白芯片及其制备方法
CN111499724A (zh) * 2020-04-15 2020-08-07 上海领潮生物新材料有限公司 一种s-腺苷同型半胱氨酸-鸡卵白蛋白偶联物的制备方法
CN115397464A (zh) * 2020-04-24 2022-11-25 美国西门子医学诊断股份有限公司 用于使用抗人免疫球蛋白抗体的抗微生物血清学测定的组合物、试剂盒和方法
EP4430215A4 (en) * 2021-11-08 2025-10-22 Summit Biolabs Inc DEVICES AND METHODS FOR TESTING STD PATHOGENS WITHOUT NUCLEIC ACID EXTRACTION
CN114316016B (zh) * 2021-12-14 2023-11-10 江苏浩欧博生物医药股份有限公司 一种Jo-1抗原生物素化的方法及抗Jo-1抗体检测试剂盒
CN115060912B (zh) * 2022-06-23 2024-02-02 南京浦光生物科技有限公司 检测目标抗体的试剂组合、试剂盒、检测系统及检测方法
EP4389913A1 (en) * 2022-12-23 2024-06-26 Universität Heidelberg A pcr-elisa analogous antibody-free method for detecting a target nucleic acid in a sample
CN116125076A (zh) * 2022-12-30 2023-05-16 广州医科大学 检测桥粒蛋白的试剂在制备肝纤维化的检测产品中的应用
CN118667920B (zh) * 2024-07-30 2024-11-12 北京华诺奥美基因生物科技有限公司 一种基于微流控的低丰度生物标志物的检测试剂盒、检测方法及其应用

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AU2016249392A1 (en) 2017-11-16
EP3283638B1 (en) 2022-06-08
CN107614699A (zh) 2018-01-19
EP3283638A1 (en) 2018-02-21
US20180100181A1 (en) 2018-04-12
US20210403978A1 (en) 2021-12-30
JP2018512862A (ja) 2018-05-24
EP4123031A1 (en) 2023-01-25
US11149296B2 (en) 2021-10-19
ZA201707114B (en) 2019-02-27
US12054768B2 (en) 2024-08-06
JP6822973B2 (ja) 2021-01-27
ES3073950T3 (en) 2026-07-16
EA201792289A1 (ru) 2018-04-30
WO2016168711A1 (en) 2016-10-20
BR112017022329A2 (pt) 2018-07-17
EP4123031B1 (en) 2026-06-03
CA2982998A1 (en) 2016-10-20
EP3283638A4 (en) 2018-09-12