EA201791184A1 - Днк-примеси в композиции, содержащей парвовирусный вирион - Google Patents

Днк-примеси в композиции, содержащей парвовирусный вирион

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Publication number
EA201791184A1
EA201791184A1 EA201791184A EA201791184A EA201791184A1 EA 201791184 A1 EA201791184 A1 EA 201791184A1 EA 201791184 A EA201791184 A EA 201791184A EA 201791184 A EA201791184 A EA 201791184A EA 201791184 A1 EA201791184 A1 EA 201791184A1
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EA
Eurasian Patent Office
Prior art keywords
virion
parvirus
composition containing
present
composition
Prior art date
Application number
EA201791184A
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English (en)
Other versions
EA035747B1 (ru
Inventor
Яцек Лубельский
Вильхельмус Теодорус Йоханнес Мария Кристиан Херменс
Original Assignee
ЮНИКЬЮРЕ АйПи Б.В.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52000715&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201791184(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ЮНИКЬЮРЕ АйПи Б.В. filed Critical ЮНИКЬЮРЕ АйПи Б.В.
Publication of EA201791184A1 publication Critical patent/EA201791184A1/ru
Publication of EA035747B1 publication Critical patent/EA035747B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14121—Viruses as such, e.g. new isolates, mutants or their genomic sequences

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Настоящее изобретение относится к примесям нуклеиновой кислоты в композиции, содержащей парвовирусный вектор. В частности, настоящее изобретение показывает, что ДНК-примеси инкапсулируются в парвовирусном вирионе не случайным образом. Таким образом, настоящее изобретение относится к способу идентификации и количественного определения примеси нуклеиновой кислоты в композиции, содержащей парвовирусный вектор. Кроме того, настоящее изобретение относится к способу определения того, является ли композиция, содержащая парвовирусный вектор, клинически чистой.
EA201791184A 2014-11-28 2015-11-27 Днк-примеси в композиции, содержащей парвовирусный вирион EA035747B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14195464 2014-11-28
PCT/EP2015/077882 WO2016083560A1 (en) 2014-11-28 2015-11-27 Dna impurities in a composition comprising a parvoviral virion

Publications (2)

Publication Number Publication Date
EA201791184A1 true EA201791184A1 (ru) 2017-09-29
EA035747B1 EA035747B1 (ru) 2020-08-05

Family

ID=52000715

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201791184A EA035747B1 (ru) 2014-11-28 2015-11-27 Днк-примеси в композиции, содержащей парвовирусный вирион

Country Status (19)

Country Link
US (2) US11021762B2 (ru)
EP (3) EP3224376B2 (ru)
JP (1) JP6741345B2 (ru)
KR (1) KR102528156B1 (ru)
CN (1) CN107208142B (ru)
AU (1) AU2015352469B2 (ru)
BR (1) BR112017011217A2 (ru)
CA (1) CA2968622A1 (ru)
CY (1) CY1122223T1 (ru)
DK (2) DK3591070T3 (ru)
EA (1) EA035747B1 (ru)
ES (1) ES2751919T5 (ru)
FI (1) FI3224376T4 (ru)
HK (1) HK1244849B (ru)
HU (1) HUE046643T2 (ru)
PL (1) PL3224376T5 (ru)
PT (1) PT3224376T (ru)
SI (1) SI3224376T2 (ru)
WO (1) WO2016083560A1 (ru)

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RU2020109343A (ru) 2014-11-05 2020-03-17 Вояджер Терапьютикс, Инк. Полинуклеотиды aadc для лечения болезни паркинсона
DK3218386T3 (da) 2014-11-14 2021-06-07 Voyager Therapeutics Inc Modulatorisk polynukleotid
MX2017006216A (es) 2014-11-14 2018-08-29 Voyager Therapeutics Inc Composiciones y métodos para tratar la esclerosis lateral amiotrófica (ela).
PL3224376T5 (pl) 2014-11-28 2023-08-21 Uniqure Ip B.V. Zanieczyszczenia DNA w kompozycji zawierającej wiriony parwowirusowe
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Also Published As

Publication number Publication date
JP2017535278A (ja) 2017-11-30
EA035747B1 (ru) 2020-08-05
EP3224376B1 (en) 2019-08-07
SI3224376T2 (sl) 2023-07-31
ES2751919T3 (es) 2020-04-02
US11021762B2 (en) 2021-06-01
FI3224376T4 (fi) 2023-08-31
US20170321290A1 (en) 2017-11-09
AU2015352469A1 (en) 2017-06-01
EP3591070B1 (en) 2022-12-21
DK3224376T3 (da) 2019-09-30
EP3224376B2 (en) 2023-04-26
SI3224376T1 (sl) 2020-01-31
CN107208142A (zh) 2017-09-26
HK1244849B (zh) 2020-04-09
DK3591070T3 (da) 2023-01-30
JP6741345B2 (ja) 2020-08-19
PT3224376T (pt) 2019-10-25
PL3224376T5 (pl) 2023-08-21
ES2751919T5 (es) 2023-10-04
PL3224376T3 (pl) 2020-03-31
CN107208142B (zh) 2024-03-26
EP3224376A1 (en) 2017-10-04
WO2016083560A1 (en) 2016-06-02
CA2968622A1 (en) 2016-06-02
EP3591070A1 (en) 2020-01-08
KR102528156B1 (ko) 2023-05-03
CY1122223T1 (el) 2020-11-25
EP4219742A1 (en) 2023-08-02
AU2015352469B2 (en) 2021-09-16
KR20170081704A (ko) 2017-07-12
DK3224376T4 (da) 2023-05-30
BR112017011217A2 (pt) 2018-02-06
US20210332447A1 (en) 2021-10-28
HUE046643T2 (hu) 2021-11-29

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