EA201791043A1 - Комбинированная терапия бокового амиотрофического склероза - Google Patents

Комбинированная терапия бокового амиотрофического склероза

Info

Publication number
EA201791043A1
EA201791043A1 EA201791043A EA201791043A EA201791043A1 EA 201791043 A1 EA201791043 A1 EA 201791043A1 EA 201791043 A EA201791043 A EA 201791043A EA 201791043 A EA201791043 A EA 201791043A EA 201791043 A1 EA201791043 A1 EA 201791043A1
Authority
EA
Eurasian Patent Office
Prior art keywords
riluzole
individual
methods
reducing
combined therapy
Prior art date
Application number
EA201791043A
Other languages
English (en)
Russian (ru)
Inventor
Джесс Седарбаум
Джон Мао
Фейди Малик
Эндрю А. Уолфф
Original Assignee
Сайтокинетикс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сайтокинетикс, Инк. filed Critical Сайтокинетикс, Инк.
Publication of EA201791043A1 publication Critical patent/EA201791043A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EA201791043A 2011-07-13 2012-07-12 Комбинированная терапия бокового амиотрофического склероза EA201791043A1 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161507381P 2011-07-13 2011-07-13
US201161544533P 2011-10-07 2011-10-07
US201261637759P 2012-04-24 2012-04-24
US201261637770P 2012-04-24 2012-04-24
US201261646699P 2012-05-14 2012-05-14

Publications (1)

Publication Number Publication Date
EA201791043A1 true EA201791043A1 (ru) 2017-09-29

Family

ID=47506929

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201791043A EA201791043A1 (ru) 2011-07-13 2012-07-12 Комбинированная терапия бокового амиотрофического склероза
EA201490011A EA028060B1 (ru) 2011-07-13 2012-07-12 Комбинированная терапия бокового амиотрофического склероза

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201490011A EA028060B1 (ru) 2011-07-13 2012-07-12 Комбинированная терапия бокового амиотрофического склероза

Country Status (16)

Country Link
US (1) US10272082B2 (OSRAM)
EP (1) EP2731611B1 (OSRAM)
JP (2) JP6145946B2 (OSRAM)
KR (1) KR101951220B1 (OSRAM)
CN (2) CN109316480A (OSRAM)
AU (2) AU2012281042B2 (OSRAM)
BR (1) BR112014000742A2 (OSRAM)
CA (1) CA2849213A1 (OSRAM)
EA (2) EA201791043A1 (OSRAM)
HK (1) HK1197178A1 (OSRAM)
IL (1) IL230391B (OSRAM)
IN (1) IN2014DN00200A (OSRAM)
PH (1) PH12014500094A1 (OSRAM)
SG (1) SG10201605707UA (OSRAM)
WO (1) WO2013010015A2 (OSRAM)
ZA (1) ZA201400236B (OSRAM)

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EP3072513A1 (en) * 2015-03-26 2016-09-28 Medday Biotin for treating Amyotrophic lateral sclerosis
US10092564B2 (en) 2016-03-25 2018-10-09 Ab Science Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation
US11439626B2 (en) 2019-09-20 2022-09-13 Icahn School Of Medicine At Mount Sinai Controlled release formulations of riluzole and their uses

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Also Published As

Publication number Publication date
JP6145946B2 (ja) 2017-06-14
EP2731611A4 (en) 2015-02-18
EA201490011A1 (ru) 2014-08-29
CN104039148A (zh) 2014-09-10
SG10201605707UA (en) 2016-09-29
KR20140074270A (ko) 2014-06-17
NZ619924A (en) 2016-02-26
IN2014DN00200A (OSRAM) 2015-06-05
AU2016244263A1 (en) 2016-11-03
AU2012281042A1 (en) 2014-01-30
PH12014500094A1 (en) 2014-03-17
EA028060B1 (ru) 2017-10-31
US20140243344A1 (en) 2014-08-28
ZA201400236B (en) 2014-10-29
CN109316480A (zh) 2019-02-12
EP2731611B1 (en) 2019-09-18
CA2849213A1 (en) 2013-01-17
EP2731611A2 (en) 2014-05-21
US10272082B2 (en) 2019-04-30
JP2014520856A (ja) 2014-08-25
JP2017128610A (ja) 2017-07-27
IL230391B (en) 2019-03-31
AU2012281042B2 (en) 2016-07-14
BR112014000742A2 (pt) 2016-08-23
KR101951220B1 (ko) 2019-02-22
WO2013010015A3 (en) 2014-05-15
HK1197178A1 (en) 2015-01-09
WO2013010015A2 (en) 2013-01-17

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