EA201790864A1 - Многостадийные биореакторные процессы - Google Patents

Многостадийные биореакторные процессы

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Publication number
EA201790864A1
EA201790864A1 EA201790864A EA201790864A EA201790864A1 EA 201790864 A1 EA201790864 A1 EA 201790864A1 EA 201790864 A EA201790864 A EA 201790864A EA 201790864 A EA201790864 A EA 201790864A EA 201790864 A1 EA201790864 A1 EA 201790864A1
Authority
EA
Eurasian Patent Office
Prior art keywords
stages
stage
bioreactor
separation
processes
Prior art date
Application number
EA201790864A
Other languages
English (en)
Other versions
EA035153B1 (ru
Inventor
Саймон Ричард Треветик
Джейсон Карл Бромли
Гай Уильям Уотерс
Михель Кёпке
Лоан Пхуонг Тран
Расмус Енсен Овергаард
Original Assignee
Ланцатек Нью Зилэнд Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ланцатек Нью Зилэнд Лимитед filed Critical Ланцатек Нью Зилэнд Лимитед
Publication of EA201790864A1 publication Critical patent/EA201790864A1/ru
Publication of EA035153B1 publication Critical patent/EA035153B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/14—Multiple stages of fermentation; Multiple types of microorganisms or re-use of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C12P7/28—Acetone-containing products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/54—Acetic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Описаны многостадийные биологические процессы и системы для превращения источника С1-углерода в желательные товарные продукты. Процессы включают разделение газообразного С1-содержащего субстрата, по параллельной схеме, между множеством биореакторных стадий. Жидкие продукты последовательно подаются, по последовательной схеме, из первой биореакторной стадии в последующие биореакторные стадии. Процесс может быть упрощен путем устранения потребности в сепарации и рециркуляции микроорганизма на каждой стадии. Кроме того, общий массоперенос пар-жидкость для комбинации стадий является очень благоприятным, приводя к высокой производительности по товарному продукту со сравнительно низкой производительностью по побочному продукту-метаболиту.
EA201790864A 2014-10-22 2015-10-22 Многостадийные биореакторные процессы EA035153B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462067405P 2014-10-22 2014-10-22
US201462067379P 2014-10-22 2014-10-22
PCT/US2015/057025 WO2016065217A1 (en) 2014-10-22 2015-10-22 Multi-stage bioreactor processes

Publications (2)

Publication Number Publication Date
EA201790864A1 true EA201790864A1 (ru) 2017-09-29
EA035153B1 EA035153B1 (ru) 2020-05-06

Family

ID=55761604

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201790864A EA035153B1 (ru) 2014-10-22 2015-10-22 Многостадийные биореакторные процессы

Country Status (16)

Country Link
US (1) US9834792B2 (ru)
EP (2) EP4198118A1 (ru)
JP (1) JP6662868B2 (ru)
KR (1) KR102531893B1 (ru)
CN (2) CN107002012B (ru)
BR (1) BR112017008128B1 (ru)
CA (1) CA2965368C (ru)
EA (1) EA035153B1 (ru)
ES (1) ES2946180T3 (ru)
FI (1) FI3209786T3 (ru)
HU (1) HUE062028T2 (ru)
PL (1) PL3209786T3 (ru)
PT (1) PT3209786T (ru)
TW (1) TWI689592B (ru)
WO (1) WO2016065217A1 (ru)
ZA (1) ZA201702862B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201810031RA (en) * 2016-05-14 2018-12-28 Lanzatech Inc Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods
ES2914725T3 (es) * 2017-03-10 2022-06-15 Dow Global Technologies Llc Sistemas y métodos de fermentación aeróbica
MY193827A (en) * 2017-09-08 2022-10-27 Lanzatech Inc Processes and systems for metabolite production using hydrogen rich c1-containing substrates
US20210071223A1 (en) * 2018-01-23 2021-03-11 Lanzatech, Inc. Two-step fermenation process for production of a product
NL2020407B1 (en) * 2018-02-09 2019-08-19 Yong Shin Hyun Bioreactor for converting gaseous co2
DE102019124650A1 (de) 2019-09-13 2021-03-18 Karlsruher Institut für Technologie Vorrichtung und Verfahren zur kontinuierlichen Fermentation von Synthesegas
CN114728223A (zh) * 2019-11-11 2022-07-08 塔卡查有限公司 用于控制生物质转化系统的系统和方法
DK3831983T3 (da) * 2019-12-04 2022-09-12 Indian Oil Corp Ltd Design af en membranløs reaktor og proces til biotransformation af kuldioxid
CN114381364A (zh) * 2020-10-22 2022-04-22 盛秸崎机械设备(上海)有限公司 一种生物酶分解法纤维分离设备及其系统

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4533211A (en) 1983-01-31 1985-08-06 International Business Machines Corporation Frequency multiplexed optical spatial filter based upon photochemical hole burning
CA1240631A (en) * 1985-06-11 1988-08-16 Bechara F. Safi Bioreactor
US5173429A (en) 1990-11-09 1992-12-22 The Board Of Trustees Of The University Of Arkansas Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
US5807722A (en) 1992-10-30 1998-09-15 Bioengineering Resources, Inc. Biological production of acetic acid from waste gases with Clostridium ljungdahlii
US5593886A (en) 1992-10-30 1997-01-14 Gaddy; James L. Clostridium stain which produces acetic acid from waste gases
UA72220C2 (ru) 1998-09-08 2005-02-15 Байоенджініерінг Рісорсиз, Інк. Translated By PlajНЕСМЕШИВАЕМАЯ С ВОДОЙ СМЕСЬ РАСТВОРИТЕЛЬ/СОРАСТВОРИТЕЛЬ ДЛЯ ЭКСТРАГИРОВАНИЯ УКСУСНОЙ КИСЛОТЫ, СПОСОБ ПОЛУЧЕНИЯ УКСУСНОЙ КИСЛОТЫ (ВАРИАНТЫ), СПОСОБ АНАЭРОБНОГО МИКРОБНОГО БРОЖЕНИЯ ДЛЯ ПОЛУЧЕНИЯ УКСУСНОЙ КИСЛОТЫ (ВАРИАНТЫ), МОДИФИЦИРОВАННЫЙ РАСТВОРИТЕЛЬ И СПОСОБ ЕГО ПОЛУЧЕНИЯ
US6415525B1 (en) 1998-10-02 2002-07-09 Marlena International, Llc Measuring article and method for sizing compression garments
EP1177309B1 (en) 1999-05-07 2004-02-18 Emmaus Foundation, Inc. Clostridium strains which produce ethanol from substrate-containing gases
CN1223679C (zh) 2000-07-25 2005-10-19 以马忤斯基金股份有限公司 提高微生物发酵生产乙醇的方法
RU2203261C1 (ru) * 2002-03-15 2003-04-27 Открытое акционерное общество "Метокс Интернейшнл" Способ получения метанола и установка для его осуществления
US20050064577A1 (en) * 2002-05-13 2005-03-24 Isaac Berzin Hydrogen production with photosynthetic organisms and from biomass derived therefrom
NZ546496A (en) 2006-04-07 2008-09-26 Lanzatech New Zealand Ltd Gas treatment process
US7704723B2 (en) 2006-08-31 2010-04-27 The Board Of Regents For Oklahoma State University Isolation and characterization of novel clostridial species
NZ553984A (en) 2007-03-19 2009-07-31 Lanzatech New Zealand Ltd Alcohol production process
WO2009022925A1 (en) 2007-08-15 2009-02-19 Lanzatech New Zealand Limited Processes of producing alcohols
NZ560757A (en) * 2007-10-28 2010-07-30 Lanzatech New Zealand Ltd Improved carbon capture in microbial fermentation of industrial gases to ethanol
KR101375029B1 (ko) 2007-11-13 2014-03-14 란자테크 뉴질랜드 리미티드 신규 세균 및 이의 이용 방법
US8309348B2 (en) * 2008-02-22 2012-11-13 Coskata, Inc. Syngas conversion method using asymmetric membrane and anaerobic microorganism
US8211679B2 (en) * 2008-02-25 2012-07-03 Coskata, Inc. Process for producing ethanol
EA018720B1 (ru) 2008-06-09 2013-10-30 Ланзатек Нью Зиленд Лимитед Способ получения бутандиола с помощью анаэробной микробной ферментации
MX2011006177A (es) * 2008-12-11 2011-06-27 Joule Unltd Inc Biofactoria solar, fotobiorreactores, sistemas pasivos de regulacion termica y metodos para producir productos.
CN102361989B (zh) 2009-01-29 2014-03-12 兰扎泰克新西兰有限公司 醇的生产方法
JP2012525145A (ja) * 2009-04-29 2012-10-22 ランザテク・ニュージーランド・リミテッド 発酵における改善された炭素捕捉
ZA201003407B (en) * 2009-05-14 2011-04-28 Univ Johannesburg Witwatersrand Bioreactor process for production of hydrogen from biomass
WO2011002318A1 (en) 2009-07-02 2011-01-06 Lanzatech New Zealand Limited Alcohol production process
CN102498214B (zh) * 2009-09-06 2013-06-19 新西兰郎泽科技公司 改进的气态底物发酵
WO2011078184A1 (ja) * 2009-12-25 2011-06-30 ダイヤニトリックス株式会社 微生物触媒を用いたアクリルアミドの製造方法
US20120040421A1 (en) 2010-03-10 2012-02-16 Lanza Tech New Zealand Limited Acid production by fermentation
WO2012024522A2 (en) 2010-08-19 2012-02-23 Lanzatech New Zealand Limited A process for producing chemicals using microbial fermentation of substrates comprising carbon monoxide
TW201224151A (en) 2010-08-26 2012-06-16 Lanzatech New Zealand Ltd A process
US20110236941A1 (en) 2010-10-22 2011-09-29 Lanzatech New Zealand Limited Recombinant microorganism and methods of production thereof
TWI541348B (zh) 2011-02-25 2016-07-11 藍瑟科技紐西蘭有限公司 重組一氧化碳營養性產乙酸微生物及其用途
CN109136291A (zh) 2011-09-08 2019-01-04 朗泽科技新西兰有限公司 一种发酵方法
US8771999B2 (en) * 2011-09-23 2014-07-08 Coskata, Inc. Low energy, high substrate efficiency, anaerobic, deep, bubble column fermentation processes
IN2014DN10168A (ru) 2012-05-30 2015-08-21 Lanzatech New Zealand Ltd
US20130323820A1 (en) 2012-06-01 2013-12-05 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
WO2013185123A1 (en) 2012-06-08 2013-12-12 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
US9347076B2 (en) 2012-06-21 2016-05-24 Lanzatech New Zealand Limited Recombinant microorganisms that make biodiesel
WO2014036152A1 (en) 2012-08-28 2014-03-06 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
CN102866193B (zh) 2012-09-04 2015-04-01 吴传勇 基于介电泳来操控液体中的粒子的器件及方法
US10233478B2 (en) * 2012-09-19 2019-03-19 Ineos Bio Sa Process for reducing CO2 emissions and increasing alcohol productivity in syngas fermentation
US9034617B2 (en) * 2013-03-14 2015-05-19 Coskata, Inc. Processes for the anaerobic bioconverison of syngas to oxygenated organic compound with in situ protection from hydrogen cyanide
MY183766A (en) * 2013-03-15 2021-03-12 Lanzatech New Zealand Ltd A system and method for controlling metabolite production in a microbial fermentation
US9988598B2 (en) * 2013-07-04 2018-06-05 Lanzatech New Zealand Limited Multiple reactor system for continuous gas fermentation
CN103555771B (zh) * 2013-11-01 2015-07-01 中国科学院广州能源研究所 一种co发酵制乙醇的生产方法及设备
CN103725605A (zh) * 2013-12-31 2014-04-16 陕西万源生物农业科技有限公司 一种发酵罐及发酵系统
GB201417362D0 (en) * 2014-10-01 2014-11-12 Hartley Brian S Devices and methods for selection of microbial strains
JP2017531441A (ja) * 2014-10-22 2017-10-26 ランザテク・ニュージーランド・リミテッド ガス試験装置及び方法
EP3411491B1 (en) * 2016-02-04 2020-09-09 Lanzatech New Zealand Limited Product management in biological conversion processes
MY193827A (en) * 2017-09-08 2022-10-27 Lanzatech Inc Processes and systems for metabolite production using hydrogen rich c1-containing substrates

Also Published As

Publication number Publication date
KR20170073653A (ko) 2017-06-28
EP3209786B1 (en) 2023-03-29
BR112017008128B1 (pt) 2023-03-14
CA2965368A1 (en) 2016-04-28
EP4198118A1 (en) 2023-06-21
CN107002012A (zh) 2017-08-01
ES2946180T3 (es) 2023-07-13
EA035153B1 (ru) 2020-05-06
CN110066718A (zh) 2019-07-30
EP3209786A4 (en) 2018-06-06
JP2017534276A (ja) 2017-11-24
WO2016065217A1 (en) 2016-04-28
PT3209786T (pt) 2023-06-26
BR112017008128A2 (pt) 2018-02-20
KR102531893B1 (ko) 2023-05-11
TW201625794A (zh) 2016-07-16
CN107002012B (zh) 2019-04-26
CN110066718B (zh) 2022-09-20
FI3209786T3 (fi) 2023-06-13
US20160115505A1 (en) 2016-04-28
PL3209786T3 (pl) 2023-10-30
US9834792B2 (en) 2017-12-05
TWI689592B (zh) 2020-04-01
CA2965368C (en) 2018-08-14
ZA201702862B (en) 2018-08-29
HUE062028T2 (hu) 2023-09-28
JP6662868B2 (ja) 2020-03-11
EP3209786A1 (en) 2017-08-30

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