EA201991240A1 - Способ и система для выделения продукта и повторного использования клеток - Google Patents

Способ и система для выделения продукта и повторного использования клеток

Info

Publication number
EA201991240A1
EA201991240A1 EA201991240A EA201991240A EA201991240A1 EA 201991240 A1 EA201991240 A1 EA 201991240A1 EA 201991240 A EA201991240 A EA 201991240A EA 201991240 A EA201991240 A EA 201991240A EA 201991240 A1 EA201991240 A1 EA 201991240A1
Authority
EA
Eurasian Patent Office
Prior art keywords
microorganisms
biomass
product
culture fluid
viability
Prior art date
Application number
EA201991240A
Other languages
English (en)
Other versions
EA037782B1 (ru
Inventor
Пол Элвин Секрист
Николас Бурдакос
Роберт Джон Конрадо
Аллан Ха Гао
Джейсон Карл Бромли
Майкл Эмерсон Мартин
Кристоф Даниэль Михалцеа
Игнаси Палоу-Ривера
Джозеф Генри Тизард
Original Assignee
Ланцатек, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ланцатек, Инк. filed Critical Ланцатек, Инк.
Publication of EA201991240A1 publication Critical patent/EA201991240A1/ru
Publication of EA037782B1 publication Critical patent/EA037782B1/ru

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D19/00—Degasification of liquids
    • B01D19/0042—Degasification of liquids modifying the liquid flow
    • B01D19/0052—Degasification of liquids modifying the liquid flow in rotating vessels, vessels containing movable parts or in which centrifugal movement is caused
    • B01D19/0057—Degasification of liquids modifying the liquid flow in rotating vessels, vessels containing movable parts or in which centrifugal movement is caused the centrifugal movement being caused by a vortex, e.g. using a cyclone, or by a tangential inlet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
    • B01D3/001—Processes specially adapted for distillation or rectification of fermented solutions
    • B01D3/002—Processes specially adapted for distillation or rectification of fermented solutions by continuous methods
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
    • B01D3/10—Vacuum distillation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D53/00—Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
    • B01D53/14—Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by absorption
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Treatment Of Sludge (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)

Abstract

Данное изобретение относится к устройству и связанному с ним способу выделения по меньшей мере одного продукта из культуральной жидкости. Данное изобретение относится к применению вакуумного дистилляционного сосуда для выделения продуктов, таких как этанол, из культуральной жидкости, в котором культуральная жидкость содержит жизнеспособную биомассу микроорганизмов и при этом выделение продукта завершается таким образом, чтобы обеспечить жизнеспособность биомассы микроорганизмов. Изобретение обеспечивает выделение продукта с эффективной скоростью, чтобы предотвратить накопление продукта в культуральной жидкости. Для обеспечения жизнеспособности биомассы микроорганизмов изобретение спроектировано для уменьшения количества нагрузки на биомассу микроорганизмов. За счет обеспечения жизнеспособности биомассы микроорганизмов биомасса микроорганизмов может быть переработана и повторно использована в процессе ферментации, что может привести к повышению эффективности процесса ферментации.
EA201991240A 2017-03-20 2018-03-20 Способ и система для выделения продукта и повторного использования клеток EA037782B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762473850P 2017-03-20 2017-03-20
PCT/US2018/023414 WO2018175481A1 (en) 2017-03-20 2018-03-20 A process and system for product recovery and cell recycle

Publications (2)

Publication Number Publication Date
EA201991240A1 true EA201991240A1 (ru) 2020-02-10
EA037782B1 EA037782B1 (ru) 2021-05-20

Family

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Family Applications (1)

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EA201991240A EA037782B1 (ru) 2017-03-20 2018-03-20 Способ и система для выделения продукта и повторного использования клеток

Country Status (13)

Country Link
US (3) US10610802B2 (ru)
EP (1) EP3538238A4 (ru)
JP (2) JP7479847B2 (ru)
KR (1) KR102642284B1 (ru)
CN (1) CN110312558B (ru)
AU (1) AU2018240178B2 (ru)
BR (1) BR112019018522A2 (ru)
CA (2) CA3046979C (ru)
EA (1) EA037782B1 (ru)
MY (1) MY185732A (ru)
SG (1) SG11201905673RA (ru)
WO (1) WO2018175481A1 (ru)
ZA (1) ZA201903663B (ru)

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Also Published As

Publication number Publication date
EP3538238A1 (en) 2019-09-18
US20220305399A1 (en) 2022-09-29
JP7479847B2 (ja) 2024-05-09
CA3046979C (en) 2020-03-24
EA037782B1 (ru) 2021-05-20
KR20190122645A (ko) 2019-10-30
CA3053053C (en) 2020-04-14
US10610802B2 (en) 2020-04-07
WO2018175481A1 (en) 2018-09-27
US20180264375A1 (en) 2018-09-20
AU2018240178A1 (en) 2019-07-18
CA3046979A1 (en) 2018-09-27
CN110312558B (zh) 2021-10-15
BR112019018522A2 (pt) 2020-04-14
US20200188809A1 (en) 2020-06-18
ZA201903663B (en) 2020-12-23
CA3053053A1 (en) 2018-09-27
CN110312558A (zh) 2019-10-08
JP2023011698A (ja) 2023-01-24
KR102642284B1 (ko) 2024-02-28
EP3538238A4 (en) 2020-01-01
JP2020511125A (ja) 2020-04-16
SG11201905673RA (en) 2019-10-30
US11471786B2 (en) 2022-10-18
MY185732A (en) 2021-06-02
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