EA201591859A1 - Фармацевтическая композиция, содержащая гиалуроновую кислоту, для использования при лечении болезни черного диска - Google Patents

Фармацевтическая композиция, содержащая гиалуроновую кислоту, для использования при лечении болезни черного диска

Info

Publication number
EA201591859A1
EA201591859A1 EA201591859A EA201591859A EA201591859A1 EA 201591859 A1 EA201591859 A1 EA 201591859A1 EA 201591859 A EA201591859 A EA 201591859A EA 201591859 A EA201591859 A EA 201591859A EA 201591859 A1 EA201591859 A1 EA 201591859A1
Authority
EA
Eurasian Patent Office
Prior art keywords
hyaluronic acid
pharmaceutical composition
composition containing
containing hyaluronic
treating black
Prior art date
Application number
EA201591859A
Other languages
English (en)
Other versions
EA028443B1 (ru
Inventor
Никола Джордан
Пьеранджело Беллато
Original Assignee
Фидиа Фармачеутичи С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фидиа Фармачеутичи С.П.А. filed Critical Фидиа Фармачеутичи С.П.А.
Publication of EA201591859A1 publication Critical patent/EA201591859A1/ru
Publication of EA028443B1 publication Critical patent/EA028443B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/432—Inhibitors, antagonists
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)

Abstract

Данное изобретение описывает и заявляет права на фармацевтические композиции в форме геля для использования при лечении дегенерации межпозвоночного диска, в частности форм дегидратации и выпадения пульпозного ядра, известные как "болезнь черного диска". Эти композиции содержат производное гиалуроновой кислоты, которое образует гидрогели с точными реологическими характеристиками, что делает его оптимальным для заполнения пульпозного ядра.
EA201591859A 2013-04-24 2014-04-23 Фармацевтическая композиция, содержащая гиалуроновую кислоту, для использования при лечении дегенерации межпозвонкового диска EA028443B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000110A ITPD20130110A1 (it) 2013-04-24 2013-04-24 Composizioni farmaceutiche comprendenti acido ialuronico per il trattamento del black disc
PCT/IB2014/060928 WO2014174450A1 (en) 2013-04-24 2014-04-23 Pharmaceutical compositions containing hyaluronic acid for use in the treatment of black disk disease

Publications (2)

Publication Number Publication Date
EA201591859A1 true EA201591859A1 (ru) 2016-04-29
EA028443B1 EA028443B1 (ru) 2017-11-30

Family

ID=48579315

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201591859A EA028443B1 (ru) 2013-04-24 2014-04-23 Фармацевтическая композиция, содержащая гиалуроновую кислоту, для использования при лечении дегенерации межпозвонкового диска

Country Status (16)

Country Link
US (1) US10064887B2 (ru)
EP (1) EP2988792B1 (ru)
CN (1) CN105188785B (ru)
CA (1) CA2910104C (ru)
CY (1) CY1119065T1 (ru)
DK (1) DK2988792T3 (ru)
EA (1) EA028443B1 (ru)
ES (1) ES2638659T3 (ru)
HK (1) HK1219063A1 (ru)
IT (1) ITPD20130110A1 (ru)
LT (1) LT2988792T (ru)
MX (1) MX353411B (ru)
PT (1) PT2988792T (ru)
SA (1) SA515370029B1 (ru)
SI (1) SI2988792T1 (ru)
WO (1) WO2014174450A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201616849D0 (en) * 2016-10-04 2016-11-16 Nat Univ Ireland Regneration of diseased intervertebral discs
WO2019057035A1 (en) * 2017-09-19 2019-03-28 The Hong Kong University Of Science And Technology BIOCOMPATIBLE MATERIAL AND METHODS OF MAKING AND USING THE SAME
IT202100032111A1 (it) 2021-12-22 2023-06-22 Fidia Farm Spa Nuovi sostituti biocompatibili dell’umor vitreo

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3482812D1 (de) 1983-10-11 1990-08-30 Fidia Spa Fraktionen von hyaluronsaeure mit pharmazeutischer aktivitaet, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
IT1263393B (it) 1993-07-30 1996-08-05 Fidia Advanced Biopolymers Srl Processo per la preparazione e purificazione di acido ialuronico ad alto peso molecolare
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US8357147B2 (en) * 2005-08-17 2013-01-22 Spinal Restoration, Inc. Method for repairing intervertebral discs
US20080075657A1 (en) * 2006-04-18 2008-03-27 Abrahams John M Biopolymer system for tissue sealing
CN101285052B (zh) * 2008-04-29 2010-06-30 中国人民解放军第三军医大学第二附属医院 一种应用于组织工程椎间盘髓核构建的种子细胞接种方法
IT1394570B1 (it) * 2009-07-02 2012-07-05 Fidia Farmaceutici Materiale biologico adatto per la terapia dell osteoartrosi del danno dei legamenti e per il trattamento delle patologie delle articolazioni.
IT1395392B1 (it) * 2009-08-27 2012-09-14 Fidia Farmaceutici Geli viscoelastici come nuovi filler
IT1402385B1 (it) 2010-09-09 2013-09-04 Fidia Farmaceutici Processo per la produzione di acido ialuronico in escherichia coli o bacillus subtilis
IT1402384B1 (it) 2010-09-09 2013-09-04 Fidia Farmaceutici Processo per la produzione di acido ialuronico in escherichia coli o bacillus megaterium
CN101954123A (zh) * 2010-10-21 2011-01-26 中国人民解放军第三军医大学第二附属医院 一种人工椎间盘复合体组织及其制备方法

Also Published As

Publication number Publication date
DK2988792T3 (en) 2017-07-31
WO2014174450A1 (en) 2014-10-30
MX353411B (es) 2018-01-10
EP2988792A1 (en) 2016-03-02
EA028443B1 (ru) 2017-11-30
LT2988792T (lt) 2017-08-25
HK1219063A1 (zh) 2017-03-24
US10064887B2 (en) 2018-09-04
EP2988792B1 (en) 2017-05-31
MX2015014868A (es) 2016-03-09
CN105188785B (zh) 2017-11-17
PT2988792T (pt) 2017-08-30
CA2910104C (en) 2021-06-08
CY1119065T1 (el) 2018-01-10
US20160067274A1 (en) 2016-03-10
CN105188785A (zh) 2015-12-23
SI2988792T1 (sl) 2017-09-29
ES2638659T3 (es) 2017-10-23
SA515370029B1 (ar) 2018-04-29
ITPD20130110A1 (it) 2014-10-25
CA2910104A1 (en) 2014-10-30

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AZ KG TJ TM