EA201591412A1 - Системы и способы для поддержки клинических решений - Google Patents

Системы и способы для поддержки клинических решений

Info

Publication number
EA201591412A1
EA201591412A1 EA201591412A EA201591412A EA201591412A1 EA 201591412 A1 EA201591412 A1 EA 201591412A1 EA 201591412 A EA201591412 A EA 201591412A EA 201591412 A EA201591412 A EA 201591412A EA 201591412 A1 EA201591412 A1 EA 201591412A1
Authority
EA
Eurasian Patent Office
Prior art keywords
systems
methods
patients
treatment
disease
Prior art date
Application number
EA201591412A
Other languages
English (en)
Inventor
Александер Цин
Дэвид Б. Джексон
Мартин Штайн
Гийом Тагланг
Штефан Брок
Александер Пикер
Теодорос Солдатос
Бернхард Зульцер
Original Assignee
Молекьюлар Хелт Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48808311&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201591412(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/EP2013/056963 external-priority patent/WO2013150039A1/en
Application filed by Молекьюлар Хелт Гмбх filed Critical Молекьюлар Хелт Гмбх
Publication of EA201591412A1 publication Critical patent/EA201591412A1/ru

Links

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/10Ploidy or copy number detection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/30Data warehousing; Computing architectures
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/20ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00ICT specially adapted for the handling or processing of medical references
    • G16H70/20ICT specially adapted for the handling or processing of medical references relating to practices or guidelines

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Theoretical Computer Science (AREA)
  • Databases & Information Systems (AREA)
  • Biomedical Technology (AREA)
  • Data Mining & Analysis (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Bioethics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrotherapy Devices (AREA)
  • Surgical Instruments (AREA)

Abstract

Настоящее изобретение относится к системам и способам для биоинформатики и обработки данных. В частности, в первом аспекте настоящее изобретение относится к способам и системам для генерации персонализированного руководства по лечению пациента и для выбора лечения пациента. В другом аспекте настоящее изобретение относится к способам и системам для выбора пациентов для клинического исследования лечения. Изобретение учитывает случаи, в которых пациенты имеют больше чем одну "действующую" аберрацию посредством объединения специфичной для пациента молекулярной информации и специфичной для лечения молекулярной информации дополнительно с клинико-молекулярной моделью заболевания, в частности присвоения оценок генам и/или белкам, которые представляют некоторые аспекты их вовлечения в заболевание. Таким образом, можно приоритизировать лечения и пациентов, которые наиболее вероятно влияют или находятся под влиянием механизма заболевания, соответственно.
EA201591412A 2013-01-29 2013-10-01 Системы и способы для поддержки клинических решений EA201591412A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361757805P 2013-01-29 2013-01-29
PCT/EP2013/056963 WO2013150039A1 (en) 2012-04-02 2013-04-02 Systems and methods for disease knowledge modeling and clinical decision support
PCT/EP2013/064621 WO2014117873A1 (en) 2013-01-29 2013-07-10 Systems and methods for clinical decision support
PCT/EP2013/070493 WO2014117875A1 (en) 2013-01-29 2013-10-01 Systems and methods for clinical decision support

Publications (1)

Publication Number Publication Date
EA201591412A1 true EA201591412A1 (ru) 2015-12-30

Family

ID=48808311

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201591411A EA201591411A1 (ru) 2013-01-29 2013-07-10 Системы и способы для поддержки клинических решений
EA201591412A EA201591412A1 (ru) 2013-01-29 2013-10-01 Системы и способы для поддержки клинических решений

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA201591411A EA201591411A1 (ru) 2013-01-29 2013-07-10 Системы и способы для поддержки клинических решений

Country Status (14)

Country Link
US (2) US20150363559A1 (ru)
EP (1) EP2951744A1 (ru)
JP (3) JP2016514291A (ru)
KR (2) KR20150113113A (ru)
CN (2) CN105144179B (ru)
AU (2) AU2013376459A1 (ru)
BR (2) BR112015017954A2 (ru)
CA (2) CA2899263A1 (ru)
CL (2) CL2015002126A1 (ru)
EA (2) EA201591411A1 (ru)
IL (2) IL240128A0 (ru)
MX (2) MX2015009780A (ru)
SG (2) SG11201505852YA (ru)
WO (2) WO2014117873A1 (ru)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106442984B (zh) 2010-04-21 2020-03-13 米密德诊断学有限公司 区分细菌与病毒感染的标记物和决定因素以及其使用方法
US10431336B1 (en) 2010-10-01 2019-10-01 Cerner Innovation, Inc. Computerized systems and methods for facilitating clinical decision making
US11398310B1 (en) 2010-10-01 2022-07-26 Cerner Innovation, Inc. Clinical decision support for sepsis
US10734115B1 (en) 2012-08-09 2020-08-04 Cerner Innovation, Inc Clinical decision support for sepsis
US11348667B2 (en) 2010-10-08 2022-05-31 Cerner Innovation, Inc. Multi-site clinical decision support
US10628553B1 (en) 2010-12-30 2020-04-21 Cerner Innovation, Inc. Health information transformation system
US8856156B1 (en) 2011-10-07 2014-10-07 Cerner Innovation, Inc. Ontology mapper
US20170083669A1 (en) * 2012-01-20 2017-03-23 International Business Machines Corporation Method and apparatus providing an online diagnostic assistant tool
CN104204803B (zh) 2012-02-09 2018-08-07 米密德诊断学有限公司 用于诊断感染的标记和决定因素和其使用方法
US10249385B1 (en) 2012-05-01 2019-04-02 Cerner Innovation, Inc. System and method for record linkage
US10769241B1 (en) 2013-02-07 2020-09-08 Cerner Innovation, Inc. Discovering context-specific complexity and utilization sequences
US11894117B1 (en) 2013-02-07 2024-02-06 Cerner Innovation, Inc. Discovering context-specific complexity and utilization sequences
US10946311B1 (en) 2013-02-07 2021-03-16 Cerner Innovation, Inc. Discovering context-specific serial health trajectories
US20140310016A1 (en) * 2013-04-12 2014-10-16 Discus Analytics, Llc Medical Treatment Methods
CA2914534C (en) * 2013-06-06 2023-07-18 Timeless Veterinary Systems Inc. Method and system for providing a treatment protocol
US10957449B1 (en) 2013-08-12 2021-03-23 Cerner Innovation, Inc. Determining new knowledge for clinical decision support
US12020814B1 (en) 2013-08-12 2024-06-25 Cerner Innovation, Inc. User interface for clinical decision support
US10483003B1 (en) 2013-08-12 2019-11-19 Cerner Innovation, Inc. Dynamically determining risk of clinical condition
US20150193583A1 (en) * 2014-01-06 2015-07-09 Cerner Innovation, Inc. Decision Support From Disparate Clinical Sources
US20170068896A1 (en) * 2014-03-03 2017-03-09 Agfa Healthcare Nv Specialisation mechanism for terminology reasoning
US20150331995A1 (en) * 2014-05-14 2015-11-19 Tiecheng Zhao Evolving contextual clinical data engine for medical data processing
EP3699930B1 (en) * 2014-08-14 2024-02-07 MeMed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
WO2016059636A1 (en) 2014-10-14 2016-04-21 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof
GB2554591A (en) * 2015-04-29 2018-04-04 Univ British Columbia Clinical support system and method
EP3297566A4 (en) * 2015-05-22 2019-02-20 CSTS Health Care Inc. BIOMARKER-CONTROLLED TARGETED MOLECULAR THERAPEUTIC COMBINATIONS BASED ON KNOWLEDGE REPRESENTATION PATH ANALYSIS
EP3298524A4 (en) 2015-05-22 2019-03-20 CSTS Health Care Inc. THERMODYNAMIC MEASUREMENTS RELATING TO PROTEIN-PROTEIN INTERACTION NETWORKS FOR THE TREATMENT OF CANCER
CA2989815A1 (en) * 2015-06-15 2016-12-22 Nantomics, Llc Systems and methods for patient-specific prediction of drug responses from cell line genomics
CN107851136B (zh) * 2015-07-29 2022-04-05 皇家飞利浦有限公司 用于对未知重要性的变体划分优先级顺序的系统和方法
US20180344239A1 (en) * 2015-11-13 2018-12-06 Segterra, Inc. Managing Evidence-Based Rules
US20170162069A1 (en) * 2015-12-02 2017-06-08 Noom, Inc. Scalable population health management tools for clinicians
CN108699583B (zh) 2016-03-03 2022-11-01 米密德诊断学有限公司 用于区分细菌和病毒感染的rna决定子
KR20240025702A (ko) * 2016-06-07 2024-02-27 일루미나, 인코포레이티드 2차 및/또는 3차 프로세싱을 수행하기 위한 생물정보학 시스템, 장치, 및 방법
EP3482201B1 (en) 2016-07-10 2022-12-14 Memed Diagnostics Ltd. Early diagnosis of infections
EP3482200B1 (en) 2016-07-10 2022-05-04 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
GB201613318D0 (en) * 2016-08-02 2016-09-14 Univ Oxford Innovation Ltd System monitor and method of system monitoring
EP3287914A1 (de) * 2016-08-23 2018-02-28 Siemens Healthcare GmbH Ermittlung von ergebnisdaten auf basis von medizinischen messdaten aus verschiedenen messungen
US11434534B2 (en) 2016-09-08 2022-09-06 Curematch, Inc. Optimizing therapeutic options in personalized medicine
US10971254B2 (en) * 2016-09-12 2021-04-06 International Business Machines Corporation Medical condition independent engine for medical treatment recommendation system
US10593429B2 (en) 2016-09-28 2020-03-17 International Business Machines Corporation Cognitive building of medical condition base cartridges based on gradings of positional statements
US10818394B2 (en) 2016-09-28 2020-10-27 International Business Machines Corporation Cognitive building of medical condition base cartridges for a medical system
US11353456B2 (en) 2016-09-29 2022-06-07 Memed Diagnostics Ltd. Methods of risk assessment and disease classification for appendicitis
WO2018060998A1 (en) 2016-09-29 2018-04-05 Memed Diagnostics Ltd. Methods of prognosis and treatment
CN109997201A (zh) * 2016-11-03 2019-07-09 皇家飞利浦有限公司 针对多种医学知识模块的利用数据驱动方法的精确临床决策支持
US10607736B2 (en) 2016-11-14 2020-03-31 International Business Machines Corporation Extending medical condition base cartridges based on SME knowledge extensions
TWI607332B (zh) * 2016-12-21 2017-12-01 國立臺灣師範大學 Correlation between persistent organic pollutants and microRNAs station
CN106971071A (zh) * 2017-03-27 2017-07-21 为朔医学数据科技(北京)有限公司 一种临床决策支持系统及方法
US20180357383A1 (en) * 2017-06-07 2018-12-13 International Business Machines Corporation Sorting Medical Concepts According to Priority
US20180357361A1 (en) * 2017-06-13 2018-12-13 Feliks Frenkel Systems and methods for identifying responders and non-responders to immune checkpoint blockade therapy
US10209260B2 (en) 2017-07-05 2019-02-19 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
CN107749312A (zh) * 2017-10-10 2018-03-02 阜阳师范学院 一种基于体外受精‑胚胎移植的管理控制系统
KR101962105B1 (ko) * 2017-10-13 2019-03-26 주식회사 유비케어 진료차트를 기록하는 장치 및 진료차트를 기록하는 방법
EP3480823A1 (en) * 2017-11-02 2019-05-08 Koninklijke Philips N.V. Clinical decision support
US10937551B2 (en) 2017-11-27 2021-03-02 International Business Machines Corporation Medical concept sorting based on machine learning of attribute value differentiation
RU2703679C2 (ru) * 2017-12-29 2019-10-21 Общество С Ограниченной Ответственностью "Интеллоджик" Способ и система поддержки принятия врачебных решений с использованием математических моделей представления пациентов
CN108335756B (zh) * 2018-01-18 2022-05-24 中山大学 鼻咽癌数据库及基于所述数据库的综合诊疗决策方法
US11475995B2 (en) 2018-05-07 2022-10-18 Perthera, Inc. Integration of multi-omic data into a single scoring model for input into a treatment recommendation ranking
US11694800B2 (en) * 2018-05-09 2023-07-04 International Business Machines Corporation Medical diagnosis system with continuous learning and reasoning
US11574718B2 (en) * 2018-05-31 2023-02-07 Perthera, Inc. Outcome driven persona-typing for precision oncology
US20200004928A1 (en) * 2018-06-29 2020-01-02 Roche Sequencing Solutions, Inc. Computing device with improved user interface for interpreting and visualizing data
US11093883B2 (en) 2018-08-03 2021-08-17 Camelot Uk Bidco Limited Apparatus, method, and computer-readable medium for determining a drug for manufacture
CN108804866B (zh) * 2018-08-21 2019-09-20 淮南师范学院 一种基于二元网络的心血管疾病药物与药靶的预测方法
EP3837693A1 (en) * 2018-10-11 2021-06-23 Siemens Healthcare GmbH Healthcare network
US12100517B2 (en) 2018-10-29 2024-09-24 Flatiron Health, Inc. Generalized biomarker model
KR102167697B1 (ko) * 2018-11-08 2020-10-19 주식회사 쓰리빌리언 증상 유사도 측정기에 대한 성능 평가 시스템 및 방법
US11735320B2 (en) 2018-12-04 2023-08-22 Merative Us L.P. Dynamic creation and manipulation of data visualizations
US11721441B2 (en) * 2019-01-15 2023-08-08 Merative Us L.P. Determining drug effectiveness ranking for a patient using machine learning
WO2020210731A1 (en) * 2019-04-10 2020-10-15 Hemex Health, Inc. Diagnostic testing devices, systems and methods
JP7404648B2 (ja) * 2019-04-25 2023-12-26 富士通株式会社 治療薬提示方法、治療薬提示装置、及び治療薬提示プログラム
CN113939881A (zh) * 2019-06-13 2022-01-14 豪夫迈·罗氏有限公司 具有用于解读和可视化纵向数据的改进的用户界面的系统和方法
US12040993B2 (en) * 2019-06-18 2024-07-16 The Calany Holding S. À R.L. Software engine virtualization and dynamic resource and task distribution across edge and cloud
US12039354B2 (en) 2019-06-18 2024-07-16 The Calany Holding S. À R.L. System and method to operate 3D applications through positional virtualization technology
US12033271B2 (en) 2019-06-18 2024-07-09 The Calany Holding S. À R.L. 3D structure engine-based computation platform
CN110364266A (zh) * 2019-06-28 2019-10-22 深圳裕策生物科技有限公司 用于指导临床肿瘤个体化用药的数据库及其构建方法和装置
EP3799057A1 (en) * 2019-09-25 2021-03-31 Koninklijke Philips N.V. Prediction tool for patient immune response to a therapy
EP3799051A1 (en) * 2019-09-30 2021-03-31 Siemens Healthcare GmbH Intra-hospital genetic profile similar search
US11730420B2 (en) 2019-12-17 2023-08-22 Cerner Innovation, Inc. Maternal-fetal sepsis indicator
CN111259112B (zh) 2020-01-14 2023-07-04 北京百度网讯科技有限公司 医疗事实的验证方法和装置
CN113496768B (zh) * 2020-03-20 2023-12-01 梅傲科技(广州)有限公司 基于病理组织的二联综合肿瘤分析系统和应用
US20230298769A1 (en) * 2020-04-10 2023-09-21 The Jackson Laboratory Systems and methods for gene variant grouping and visualization
JP7565186B2 (ja) * 2020-10-23 2024-10-10 株式会社日立ハイテク 治療方針立案支援装置
US12014281B2 (en) 2020-11-19 2024-06-18 Merative Us L.P. Automatic processing of electronic files to identify genetic variants
CN112735520B (zh) * 2021-02-03 2021-07-20 深圳裕康医学检验实验室 肿瘤个体化免疫治疗基因检测结果的解读方法、系统和存储介质
US20220261668A1 (en) * 2021-02-12 2022-08-18 Tempus Labs, Inc. Artificial intelligence engine for directed hypothesis generation and ranking
US20220399092A1 (en) * 2021-06-10 2022-12-15 Rajant Health Inc. Ai-enabled health platform
CN113724806A (zh) * 2021-08-03 2021-11-30 邢传华 确定临床试验入组对象、适用药物的方法、设备和介质
CN113889279B (zh) * 2021-09-28 2022-08-05 北京华彬立成科技有限公司 联合疗法信息挖掘和查询方法、装置和电子设备
TWI796228B (zh) 2022-05-25 2023-03-11 臺中榮民總醫院 急性腎損傷預測系統及其方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6108635A (en) * 1996-05-22 2000-08-22 Interleukin Genetics, Inc. Integrated disease information system
US6081786A (en) * 1998-04-03 2000-06-27 Triangle Pharmaceuticals, Inc. Systems, methods and computer program products for guiding the selection of therapeutic treatment regimens
US6581038B1 (en) * 1999-03-15 2003-06-17 Nexcura, Inc. Automated profiler system for providing medical information to patients
EP1176539A1 (en) * 2000-07-13 2002-01-30 Virology Networks B.V. Method for effecting computer implemented decision-support in the selection of the drug therapy of patients having a viral disease
AU2002221800A1 (en) * 2000-11-02 2002-05-15 Epigenomics Ag Systems, methods and computer program products for guiding the selection of therapeutic treatment regimens
EP1953244A1 (en) * 2002-01-09 2008-08-06 Nakamura, Yusuke Cancer profiles
JP3903420B2 (ja) * 2002-02-14 2007-04-11 国立国際医療センター総長 塩基配列からrnaの機能性部位を同定するシステム
JP3563394B2 (ja) * 2002-03-26 2004-09-08 株式会社日立製作所 画面表示システム
EP1378853A1 (fr) * 2002-07-04 2004-01-07 GE Medical Systems Global Technology Company LLC Système numérique d'assistance médicale
US8688385B2 (en) 2003-02-20 2014-04-01 Mayo Foundation For Medical Education And Research Methods for selecting initial doses of psychotropic medications based on a CYP2D6 genotype
US20060062859A1 (en) * 2004-08-05 2006-03-23 Kenneth Blum Composition and method to optimize and customize nutritional supplement formulations by measuring genetic and metabolomic contributing factors to disease diagnosis, stratification, prognosis, metabolism, and therapeutic outcomes
JP2006323830A (ja) * 2005-04-18 2006-11-30 Japan Biological Informatics Consortium 表現型に関連する候補遺伝子の探索システム
WO2006119464A1 (en) * 2005-05-04 2006-11-09 University Of South Florida Predicting treatment response in cancer subjects
ES2529211T3 (es) * 2005-11-29 2015-02-18 Children's Hospital Medical Center Optimización e individualización de la selección y dosificación de medicamentos
US20070238094A1 (en) * 2005-12-09 2007-10-11 Baylor Research Institute Diagnosis, prognosis and monitoring of disease progression of systemic lupus erythematosus through blood leukocyte microarray analysis
IL282783B2 (en) * 2006-05-18 2023-09-01 Caris Mpi Inc A system and method for determining a personalized medical intervention for a disease stage
RU2473555C2 (ru) 2006-12-19 2013-01-27 ДжинГоу, Инк. Новые способы функционального анализа большого количества экспериментальных данных и групп генов, идентифицированных из указанных данных
AU2009210848B2 (en) * 2008-02-08 2013-12-19 Phadia Ab Method, computer program product and system for enabling clinical decision support
BRPI0922849B1 (pt) * 2008-12-10 2023-01-24 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc Composição de vacina com uma quantidade eficaz de um peptídeo gp2 e de gm-csf
GB0912190D0 (en) * 2009-07-13 2009-08-26 Univ Surrey Biomarker
RU2573218C2 (ru) * 2009-09-04 2016-01-20 Конинклейке Филипс Электроникс Н.В. Поддержка принятия клинических решений
WO2012006056A2 (en) * 2010-06-29 2012-01-12 Oregon Health & Science University Ccr6 as a biomarker of alzheimer's disease
US20120016594A1 (en) 2010-07-02 2012-01-19 Coriell Institute For Medical Research, Inc. Method for translating genetic information for use in pharmacogenomic molecular diagnostics and personalized medicine research
US20120172674A1 (en) * 2010-12-30 2012-07-05 General Electronic Company Systems and methods for clinical decision support

Also Published As

Publication number Publication date
BR112015017858A2 (pt) 2017-07-11
IL240128A0 (en) 2015-09-24
CN105144178B (zh) 2018-11-27
AU2013376459A1 (en) 2015-08-06
JP2016513303A (ja) 2016-05-12
JP6305437B2 (ja) 2018-04-04
SG11201505854QA (en) 2015-08-28
CN105144178A (zh) 2015-12-09
WO2014117875A1 (en) 2014-08-07
US20150363559A1 (en) 2015-12-17
SG11201505852YA (en) 2015-08-28
CL2015002126A1 (es) 2016-06-17
US10672514B2 (en) 2020-06-02
KR20150113113A (ko) 2015-10-07
JP2016514291A (ja) 2016-05-19
JP2018139111A (ja) 2018-09-06
CN105144179A (zh) 2015-12-09
EA201591411A1 (ru) 2016-01-29
BR112015017954A2 (pt) 2017-07-11
CN105144179B (zh) 2019-05-17
CA2899264A1 (en) 2014-08-07
EP2951744A1 (en) 2015-12-09
WO2014117873A1 (en) 2014-08-07
CA2899264C (en) 2021-05-11
IL240127A0 (en) 2015-09-24
MX2015009780A (es) 2016-04-04
KR20150120390A (ko) 2015-10-27
AU2013376380A1 (en) 2015-08-06
US20150370982A1 (en) 2015-12-24
JP6662933B2 (ja) 2020-03-11
MX2015009781A (es) 2016-06-16
CA2899263A1 (en) 2014-08-07
CL2015002127A1 (es) 2016-06-17

Similar Documents

Publication Publication Date Title
EA201591412A1 (ru) Системы и способы для поддержки клинических решений
BR112015003509A2 (pt) sistema de suporte clínico, meio não transitório de armazenamento legível em computador contendo instruções para execução por meio de um processador, e programa de computador
Danial et al. Ageing in iran
Jankovic et al. The future of research in Parkinson disease
NZ762886A (en) Control system for control of distribution of medication
EA201800099A1 (ru) Сенсорный пользовательский интерфейс устройства стимуляции воздуха в трахеобронхиальных путях, устройство стимуляции воздуха в трахеобронхиальных путях
CY1123926T1 (el) Αντισωματα κατα της τρανσγλουταμινασης 2
BR112017007285A2 (pt) ?método e sistema para prever débito cardíaco contínuo (cco) de um paciente baseado em dados fisiológicos?
EA201401353A1 (ru) Биомаркеры для определения эффективной ответной реакции на лечение пациентов с гепатоцеллюлярной карциномой (гцк)
Saunus et al. Breast cancer brain metastases: clonal evolution in clinical context
BR112018009664A2 (pt) plataforma de rastreamento de resultados de pacientes
Kissane et al. Psychotherapy for depression in cancer and palliative care
BR112017004729A2 (pt) processo de tratamento de doenças causadas por metástase óssea, medicamentos para as mesmas e processo de previsão do resultado clínico de tratamento de doenças causadas por metástase óssea
DeWeerdt Calling cancer's bluff with neoantigen vaccines.
EA201490548A1 (ru) Молекулярно-генетический подход для лечения и диагностики алкогольной и наркотической зависимости
BR112017021809A2 (pt) avaliação de riscos associados com fármacos terapêuticos
Edmonds et al. Establishing goals of care at any stage of illness: The PERSON mnemonic
WO2019178379A3 (en) Precision medicine for pain: diagnostic biomarkers, pharmacogenomics, and repurposed drugs
Giordani et al. Advances in understanding and treatment of human African trypanosomiasis: divergent diseases caused by distinct parasites
Lancet Social media: how doctors can contribute
Merész et al. " IS THE CRISIS AN OPPORTUNITY OR A CURSE?" VII TH IME-META ADVANCED TRAINING AND CONFERENCE ON HEALTH ECONOMICS
DEWEERDT Calling cancer’s bluff
赵玉洲 Anatomy of splenic flexure and surgical treatment in 52 patients with non-obstructive splenic flexure colon cancer
Milano et al. Trastuzumab and cardiac outcomes in breast cancer: a story we know by heart?
towards Counseling Help Seeking Behaviors of International Students