EA201591213A1 - Вакцины против вируса гепатита b - Google Patents
Вакцины против вируса гепатита bInfo
- Publication number
- EA201591213A1 EA201591213A1 EA201591213A EA201591213A EA201591213A1 EA 201591213 A1 EA201591213 A1 EA 201591213A1 EA 201591213 A EA201591213 A EA 201591213A EA 201591213 A EA201591213 A EA 201591213A EA 201591213 A1 EA201591213 A1 EA 201591213A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- virus
- seq
- amino acids
- vaccines against
- cell epitope
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/02—Hepadnaviridae, e.g. hepatitis B virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10171—Demonstrated in vivo effect
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1223386.2A GB201223386D0 (en) | 2012-12-24 | 2012-12-24 | Vaccine |
| PCT/GB2013/053410 WO2014102540A1 (en) | 2012-12-24 | 2013-12-20 | Vaccines against hepatitis b virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201591213A1 true EA201591213A1 (ru) | 2016-02-29 |
Family
ID=47682590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201591213A EA201591213A1 (ru) | 2012-12-24 | 2013-12-20 | Вакцины против вируса гепатита b |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US10300132B2 (https=) |
| EP (2) | EP3995146A1 (https=) |
| JP (3) | JP6811014B2 (https=) |
| KR (3) | KR102625645B1 (https=) |
| CN (2) | CN104903343A (https=) |
| CA (1) | CA2895459A1 (https=) |
| DK (1) | DK2935313T3 (https=) |
| EA (1) | EA201591213A1 (https=) |
| ES (1) | ES2906110T3 (https=) |
| GB (1) | GB201223386D0 (https=) |
| PL (1) | PL2935313T3 (https=) |
| WO (1) | WO2014102540A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0408164D0 (en) * | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
| GB201022147D0 (en) * | 2010-12-31 | 2011-02-16 | Immune Targeting Systems Its Ltd | Formulation |
| GB201223386D0 (en) * | 2012-12-24 | 2013-02-06 | Immune Targeting Systems Its Ltd | Vaccine |
| WO2016020538A1 (en) * | 2014-08-08 | 2016-02-11 | Transgene Sa | Hbv vaccine and antibody combination therapy to treat hbv infections |
| CN106610423A (zh) * | 2015-10-26 | 2017-05-03 | 复旦大学 | 评价疫苗疗效的细胞免疫学检测试剂盒及其储存方法 |
| WO2017207814A1 (en) | 2016-06-02 | 2017-12-07 | Ultimovacs As | A vaccine in combination with an immune checkpoint inhibitor for use in treating cancer |
| KR20190020098A (ko) | 2016-06-20 | 2019-02-27 | 아이에스에이 파마슈티컬즈 비.브이. | 펩타이드 백신의 제형 |
| CN111867624A (zh) * | 2017-12-19 | 2020-10-30 | 杨森科学爱尔兰无限公司 | 乙型肝炎病毒(hbv)疫苗的递送方法和装置 |
| JP2021520414A (ja) * | 2018-04-04 | 2021-08-19 | アルティミューン インコーポレーティッド | Ｔ細胞を誘発するワクチン組成物の組合せ及びその使用 |
| CN113939527B (zh) * | 2019-01-11 | 2025-10-28 | 新加坡科技研究局 | Hla-a*11:01限制性乙型肝炎病毒(hbv)肽用于鉴别hbv特异性cd8+ t细胞的用途 |
| US20220324916A1 (en) * | 2019-06-18 | 2022-10-13 | Janssen Sciences Ireland Unlimited Company | Hepatitis B Virus (HBV) Vaccines and Uses Thereof |
| EP4021923A1 (en) * | 2019-08-29 | 2022-07-06 | VIR Biotechnology, Inc. | Hepatitis b virus vaccines |
| US20230242590A1 (en) | 2019-12-07 | 2023-08-03 | Isa Pharmaceuticals B.V. | Treatment of diseases related to hepatitis b virus |
| IL294387A (en) * | 2020-01-09 | 2022-08-01 | Virion Therapeutics Llc | Adenovirus vectors encoding hepatitis b virus antigens fused to herpesvirus glycoprotein d and methods of using them |
| MX2022015206A (es) * | 2020-06-08 | 2023-01-05 | Hoffmann La Roche | Anticuerpos anti-hbv y metodos de uso. |
| WO2023085956A1 (en) * | 2021-11-09 | 2023-05-19 | Avalia Immunotherapies Limited | Novel therapeutic vaccines |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA926440B (en) * | 1991-08-26 | 1993-06-07 | Scripps Research Inst | Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus. |
| US6607727B1 (en) * | 1991-08-26 | 2003-08-19 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus |
| DK0726758T3 (da) * | 1993-08-02 | 2003-03-03 | Scripps Research Inst | Peptider til inducering af cytotoksiske T-lymfocytreaktioner over for hepaptitis B virus |
| JP2004508320A (ja) * | 2000-09-08 | 2004-03-18 | エピミューン インコーポレイテッド | ペプチドおよび核酸組成物を用いるｂ型肝炎ウイルスに対する細胞性免疫応答の誘導 |
| GB0408164D0 (en) * | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
| US10076570B2 (en) * | 2009-08-07 | 2018-09-18 | Transgene S.A. | Composition for treating HBV infection |
| GB201022147D0 (en) | 2010-12-31 | 2011-02-16 | Immune Targeting Systems Its Ltd | Formulation |
| GB201223386D0 (en) * | 2012-12-24 | 2013-02-06 | Immune Targeting Systems Its Ltd | Vaccine |
-
2012
- 2012-12-24 GB GBGB1223386.2A patent/GB201223386D0/en not_active Ceased
-
2013
- 2013-12-20 US US14/655,041 patent/US10300132B2/en active Active
- 2013-12-20 CN CN201380067602.2A patent/CN104903343A/zh active Pending
- 2013-12-20 EP EP21201879.0A patent/EP3995146A1/en not_active Withdrawn
- 2013-12-20 DK DK13814593.3T patent/DK2935313T3/da active
- 2013-12-20 ES ES13814593T patent/ES2906110T3/es active Active
- 2013-12-20 KR KR1020237003896A patent/KR102625645B1/ko active Active
- 2013-12-20 EA EA201591213A patent/EA201591213A1/ru unknown
- 2013-12-20 KR KR1020157020103A patent/KR102358621B1/ko not_active Expired - Fee Related
- 2013-12-20 CN CN202111025902.7A patent/CN114028553A/zh active Pending
- 2013-12-20 CA CA2895459A patent/CA2895459A1/en active Pending
- 2013-12-20 JP JP2015548778A patent/JP6811014B2/ja not_active Expired - Fee Related
- 2013-12-20 PL PL13814593T patent/PL2935313T3/pl unknown
- 2013-12-20 KR KR1020227003308A patent/KR102497063B1/ko active Active
- 2013-12-20 WO PCT/GB2013/053410 patent/WO2014102540A1/en not_active Ceased
- 2013-12-20 EP EP13814593.3A patent/EP2935313B1/en active Active
-
2018
- 2018-10-04 JP JP2018189011A patent/JP7187237B2/ja active Active
-
2019
- 2019-05-27 US US16/423,149 patent/US11382969B2/en active Active
-
2021
- 2021-02-19 JP JP2021025254A patent/JP7235785B2/ja active Active
-
2022
- 2022-07-09 US US17/861,189 patent/US11918645B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| KR20220019846A (ko) | 2022-02-17 |
| KR102358621B1 (ko) | 2022-02-03 |
| JP7235785B2 (ja) | 2023-03-08 |
| EP2935313B1 (en) | 2021-11-24 |
| GB201223386D0 (en) | 2013-02-06 |
| KR20150098676A (ko) | 2015-08-28 |
| US20230090379A1 (en) | 2023-03-23 |
| KR102497063B1 (ko) | 2023-02-06 |
| US20160106830A1 (en) | 2016-04-21 |
| JP7187237B2 (ja) | 2022-12-12 |
| US10300132B2 (en) | 2019-05-28 |
| EP3995146A1 (en) | 2022-05-11 |
| ES2906110T3 (es) | 2022-04-13 |
| US11382969B2 (en) | 2022-07-12 |
| JP6811014B2 (ja) | 2021-01-13 |
| US11918645B2 (en) | 2024-03-05 |
| CN104903343A (zh) | 2015-09-09 |
| PL2935313T3 (pl) | 2022-05-02 |
| KR20230021771A (ko) | 2023-02-14 |
| CA2895459A1 (en) | 2014-07-03 |
| JP2016505589A (ja) | 2016-02-25 |
| DK2935313T3 (da) | 2022-02-28 |
| US20200016263A1 (en) | 2020-01-16 |
| KR102625645B1 (ko) | 2024-01-15 |
| JP2021098711A (ja) | 2021-07-01 |
| EP2935313A1 (en) | 2015-10-28 |
| CN114028553A (zh) | 2022-02-11 |
| JP2019034946A (ja) | 2019-03-07 |
| WO2014102540A1 (en) | 2014-07-03 |
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