EA201492031A1 - Способы лечения диабетической ретинопатии и других офтальмологических заболеваний - Google Patents
Способы лечения диабетической ретинопатии и других офтальмологических заболеванийInfo
- Publication number
- EA201492031A1 EA201492031A1 EA201492031A EA201492031A EA201492031A1 EA 201492031 A1 EA201492031 A1 EA 201492031A1 EA 201492031 A EA201492031 A EA 201492031A EA 201492031 A EA201492031 A EA 201492031A EA 201492031 A1 EA201492031 A1 EA 201492031A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- treatment
- methods
- patient
- diabetic retinopathy
- ophthalmological diseases
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D309/06—Radicals substituted by oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
В изобретении предложены способы лечения офтальмологических заболеваний или состояний, таких как офтальмологическое заболевание или нарушение, связанное с диабетом, у пациента. Кроме того, в предложены способы лечения ретинопатии недоношенных у пациента. Дополнительно предложен способ лечения возрастной макулярной дегенерации у пациента. Способы включают введение соединений, раскрытых здесь, пациенту, нуждающемуся в этом, которые ингибируют или замедляют один или более признаков или симптомов таких состояний.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261643051P | 2012-05-04 | 2012-05-04 | |
US201261643058P | 2012-05-04 | 2012-05-04 | |
US201261643178P | 2012-05-04 | 2012-05-04 | |
US201361781907P | 2013-03-14 | 2013-03-14 | |
PCT/US2013/039562 WO2013166449A2 (en) | 2012-05-04 | 2013-05-03 | Methods for the treatment of diabetic retinopathy and other ophthalmic diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201492031A1 true EA201492031A1 (ru) | 2015-05-29 |
Family
ID=49515046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201492031A EA201492031A1 (ru) | 2012-05-04 | 2013-05-03 | Способы лечения диабетической ретинопатии и других офтальмологических заболеваний |
Country Status (18)
Country | Link |
---|---|
US (3) | US9957224B2 (ru) |
EP (2) | EP3741742A1 (ru) |
JP (5) | JP2015518491A (ru) |
KR (1) | KR20150013240A (ru) |
CN (3) | CN116850163A (ru) |
AU (1) | AU2013256029A1 (ru) |
BR (1) | BR112014027571B1 (ru) |
CA (1) | CA2872433C (ru) |
EA (1) | EA201492031A1 (ru) |
ES (1) | ES2792923T3 (ru) |
HK (2) | HK1203478A1 (ru) |
IL (1) | IL235446A0 (ru) |
MX (2) | MX2014013341A (ru) |
PH (1) | PH12014502449A1 (ru) |
SG (1) | SG11201407162SA (ru) |
TW (1) | TW201406707A (ru) |
WO (1) | WO2013166449A2 (ru) |
ZA (1) | ZA201408592B (ru) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2701116C (en) | 2007-10-05 | 2013-02-05 | Acucela Inc. | Alkoxy compounds for disease treatment |
EP2804605A4 (en) | 2012-01-20 | 2015-07-08 | Acucela Inc | SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASES |
TW201406707A (zh) | 2012-05-04 | 2014-02-16 | Acucela Inc | 用以治療糖尿病性視網膜病變及其他眼部疾病之方法 |
WO2014164905A1 (en) * | 2013-03-12 | 2014-10-09 | Acucela Inc. | Substituted 3-phenylpropylamine derivatives for the treatment of ophthalmic diseases and disorders |
EP2967999B1 (en) | 2013-03-14 | 2017-04-19 | Optimedica Corporation | Laser capsulovitreotomy |
JP6692795B2 (ja) * | 2014-04-10 | 2020-05-13 | ランケナー インスティテュート フォー メディカル リサーチ | 眼疾患および眼障害の治療のための方法および組成物 |
WO2017062990A1 (en) * | 2015-10-09 | 2017-04-13 | Case Western Reserve University | Compositions and methods for the delivery of nucleic acids |
EP3585366A4 (en) | 2017-02-27 | 2021-08-04 | Case Western Reserve University | VISUAL CYCLE MODULATORS |
CN111526779B (zh) * | 2017-12-28 | 2023-07-11 | 株式会社尼康 | 图像处理方法、图像处理程序、图像处理装置、图像显示装置、以及图像显示方法 |
MX2018008165A (es) * | 2018-06-29 | 2019-12-30 | Centro De Retina Medica Y Quirurgica S C | Sistema portátil para la identificación de casos potenciales de edema macular diabético mediante procesamiento de imagen e inteligencia artificial. |
JP2021529068A (ja) | 2018-07-07 | 2021-10-28 | アキュセラ インコーポレイテッド | 網膜低酸素症を防止するためのデバイス |
EP3830636A4 (en) | 2018-07-30 | 2022-04-13 | Acucela Inc. | ELECTRONIC CONTACT LENS OPTICAL DESIGNS TO SLOW THE PROGRESSION OF MYOPIA |
EP3866807A1 (en) * | 2018-10-16 | 2021-08-25 | F. Hoffmann-La Roche AG | Use of akt inhibitors in ophthalmology |
WO2020081941A1 (en) * | 2018-10-19 | 2020-04-23 | Medicinova, Inc. | Methods of treating ophthalmic disease/disorder or injury with ibudilast |
WO2020240867A1 (ja) * | 2019-05-31 | 2020-12-03 | 株式会社ニコン | 画像処理方法、画像処理装置、及び画像処理プログラム |
WO2021022193A1 (en) | 2019-07-31 | 2021-02-04 | Acucela Inc. | Device for projecting images on the retina |
JP2022547621A (ja) | 2019-09-16 | 2022-11-14 | アキュセラ インコーポレイテッド | 近視の進行を阻害するように設計される、電子ソフトコンタクトレンズのための組立プロセス |
WO2021168481A1 (en) | 2020-02-21 | 2021-08-26 | Acucela Inc. | Charging case for electronic contact lens |
CN111617313B (zh) * | 2020-04-29 | 2022-09-06 | 天津医科大学眼科医院 | 一种眼用线性凝胶在作为临床孔源性视网膜脱离药物方面中的应用 |
KR20230003191A (ko) | 2020-05-13 | 2023-01-05 | 어큐셀라 인코포레이티드 | 근시 치료를 위한 전자식 스위칭 가능한 안경 |
AU2021289593A1 (en) | 2020-06-08 | 2022-10-20 | Acucela Inc. | Projection of defocused images on the peripheral retina to treat refractive error |
AU2021287803A1 (en) | 2020-06-08 | 2022-10-27 | Acucela Inc. | Stick on devices using peripheral defocus to treat progressive refractive error |
CN115698832A (zh) | 2020-06-08 | 2023-02-03 | 奥克塞拉有限公司 | 用于治疗散光的非对称投影透镜 |
US11281022B2 (en) | 2020-06-10 | 2022-03-22 | Acucela Inc. | Apparatus and methods for the treatment of refractive error using active stimulation |
US11209672B1 (en) | 2021-04-06 | 2021-12-28 | Acucela Inc. | Supporting pillars for encapsulating a flexible PCB within a soft hydrogel contact lens |
US11366341B1 (en) | 2021-05-04 | 2022-06-21 | Acucela Inc. | Electronic case for electronic spectacles |
AU2022278549A1 (en) * | 2021-05-16 | 2023-12-07 | Metanoia Bio Inc. | Methods and compositions for treating ocular neovascular disease |
JPWO2022255332A1 (ru) * | 2021-06-03 | 2022-12-08 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9022788D0 (en) | 1990-10-19 | 1990-12-05 | Cortecs Ltd | Pharmaceutical formulations |
US20030181531A1 (en) * | 2003-02-11 | 2003-09-25 | David Sherris | Compositions and methods of administering tubulin binding agents for the treatment of ocular diseases |
EA006746B1 (ru) * | 2001-11-09 | 2006-04-28 | Айтек Фармасьютикалз | Способы лечения глазных неоваскулярных заболеваний |
AU2005221283C1 (en) * | 2004-03-17 | 2011-02-03 | Lars Michael Larsen | Prevention of retinopathy by inhibition of the visual cycle |
US8969415B2 (en) * | 2006-12-01 | 2015-03-03 | Allergan, Inc. | Intraocular drug delivery systems |
US20090170841A1 (en) | 2007-04-20 | 2009-07-02 | Acucela Inc. | Styrenyl Derivative Compounds for Treating Ophthalmic Diseases and Disorders |
AU2008271051C1 (en) * | 2007-06-29 | 2012-10-04 | Acucela Inc. | Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders |
CA2701116C (en) * | 2007-10-05 | 2013-02-05 | Acucela Inc. | Alkoxy compounds for disease treatment |
RU2536040C2 (ru) | 2007-11-01 | 2014-12-20 | Акусела Инк. | Производные амина и их применение для лечения офтальмологических заболеваний и расстройств |
NZ592057A (en) | 2008-09-05 | 2013-01-25 | Acucela Inc | Sulfur-linked compounds for treating opthalmic diseases and disorders |
MX2011004315A (es) | 2008-10-22 | 2011-08-24 | Acucela Inc | Compuestos para el tratamiento de enfermedades y transtornos oftalmologicos. |
EP2448569B1 (en) | 2009-07-02 | 2021-10-27 | Acucela, Inc. | Pharmacology of visual cycle modulators |
TW201406707A (zh) | 2012-05-04 | 2014-02-16 | Acucela Inc | 用以治療糖尿病性視網膜病變及其他眼部疾病之方法 |
-
2013
- 2013-04-30 TW TW102115446A patent/TW201406707A/zh unknown
- 2013-05-03 CN CN202310810454.4A patent/CN116850163A/zh active Pending
- 2013-05-03 JP JP2015510493A patent/JP2015518491A/ja active Pending
- 2013-05-03 WO PCT/US2013/039562 patent/WO2013166449A2/en active Application Filing
- 2013-05-03 SG SG11201407162SA patent/SG11201407162SA/en unknown
- 2013-05-03 CN CN201710706410.1A patent/CN107865830A/zh active Pending
- 2013-05-03 US US13/887,243 patent/US9957224B2/en active Active
- 2013-05-03 AU AU2013256029A patent/AU2013256029A1/en not_active Abandoned
- 2013-05-03 MX MX2014013341A patent/MX2014013341A/es active IP Right Grant
- 2013-05-03 CN CN201380035735.1A patent/CN104411678A/zh active Pending
- 2013-05-03 KR KR1020147034091A patent/KR20150013240A/ko not_active Application Discontinuation
- 2013-05-03 EA EA201492031A patent/EA201492031A1/ru unknown
- 2013-05-03 EP EP20169968.3A patent/EP3741742A1/en active Pending
- 2013-05-03 ES ES13784718T patent/ES2792923T3/es active Active
- 2013-05-03 EP EP13784718.2A patent/EP2844636B1/en active Active
- 2013-05-03 BR BR112014027571-8A patent/BR112014027571B1/pt active IP Right Grant
- 2013-05-03 MX MX2020001835A patent/MX2020001835A/es unknown
- 2013-05-03 CA CA2872433A patent/CA2872433C/en active Active
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2014
- 2014-11-02 IL IL235446A patent/IL235446A0/en unknown
- 2014-11-03 PH PH12014502449A patent/PH12014502449A1/en unknown
- 2014-11-21 ZA ZA2014/08592A patent/ZA201408592B/en unknown
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2015
- 2015-04-21 HK HK15103833.8A patent/HK1203478A1/xx unknown
- 2015-04-21 HK HK18106035.4A patent/HK1246646A1/zh unknown
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2017
- 2017-11-07 JP JP2017214372A patent/JP2018024702A/ja active Pending
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2018
- 2018-04-30 US US15/967,080 patent/US10730825B2/en active Active
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2019
- 2019-10-11 JP JP2019187273A patent/JP2020023535A/ja active Pending
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2020
- 2020-07-21 US US16/934,715 patent/US11795136B2/en active Active
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2021
- 2021-02-18 JP JP2021024721A patent/JP2021075576A/ja active Pending
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2023
- 2023-02-28 JP JP2023029073A patent/JP2023059991A/ja active Pending
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