EA201100654A1 - Соединения для лечения офтальмологических заболеваний и расстройств - Google Patents

Соединения для лечения офтальмологических заболеваний и расстройств

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Publication number
EA201100654A1
EA201100654A1 EA201100654A EA201100654A EA201100654A1 EA 201100654 A1 EA201100654 A1 EA 201100654A1 EA 201100654 A EA201100654 A EA 201100654A EA 201100654 A EA201100654 A EA 201100654A EA 201100654 A1 EA201100654 A1 EA 201100654A1
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Eurasian Patent Office
Prior art keywords
disorders
connections
treatment
ophthalmic diseases
compounds
Prior art date
Application number
EA201100654A
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English (en)
Inventor
Йен Л. Скотт
Владимир А. Кукса
Фенг Хонг
Рё Кубота
Дженнифер Гейдж
Original Assignee
Акусела, Инк.
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Application filed by Акусела, Инк. filed Critical Акусела, Инк.
Publication of EA201100654A1 publication Critical patent/EA201100654A1/ru

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    • C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/31—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
    • C07C311/33—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings
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Abstract

Описаны соединения и их фармацевтические композиции, а также способы лечения офтальмологических заболеваний и расстройств, таких как возрастная макулярная дегенерация и заболевание Штаргардта с использованием указанных соединений и композиций.
EA201100654A 2008-10-22 2009-10-21 Соединения для лечения офтальмологических заболеваний и расстройств EA201100654A1 (ru)

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PCT/US2009/061545 WO2010048332A2 (en) 2008-10-22 2009-10-21 Compounds for treating ophthalmic diseases and disorders

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