EA201290689A1 - Лечение стрептококковых инфекций - Google Patents

Лечение стрептококковых инфекций

Info

Publication number
EA201290689A1
EA201290689A1 EA201290689A EA201290689A EA201290689A1 EA 201290689 A1 EA201290689 A1 EA 201290689A1 EA 201290689 A EA201290689 A EA 201290689A EA 201290689 A EA201290689 A EA 201290689A EA 201290689 A1 EA201290689 A1 EA 201290689A1
Authority
EA
Eurasian Patent Office
Prior art keywords
striptokokkovyy
infections
treatment
protein
streptococcus pneumoniae
Prior art date
Application number
EA201290689A
Other languages
English (en)
Other versions
EA023702B1 (ru
Inventor
Филипп Деноэль
Филипп Винсент Эрман
Стив Лабб
Ян Пулман
Стефан Риу
Original Assignee
Глаксосмитклайн Байолоджикалс С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Глаксосмитклайн Байолоджикалс С.А. filed Critical Глаксосмитклайн Байолоджикалс С.А.
Publication of EA201290689A1 publication Critical patent/EA201290689A1/ru
Publication of EA023702B1 publication Critical patent/EA023702B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A

Abstract

В настоящем изобретении раскрыт способ лечения или предотвращения инфекции, обусловленной Streptococcus pneumoniaeразвивающейся в среде, где концентрация свободного Znи/или Mnдостаточно низка для повышающей регуляции экспрессии по меньшей мере одного белка семейства полигистидиновой триады (polyhistidine triad family) (белка PhtX) (например, PhtD) у Streptococcus pneumoniaeвключающий стадию введения фармацевтически эффективного количества белка PhtX пациенту-человеку.
EA201290689A 2010-03-09 2011-03-08 СПОСОБ ЛЕЧЕНИЯ ИЛИ ПРЕДОТВРАЩЕНИЯ ИНФЕКЦИИ STREPTOCOCCUS PNEUMONIA И ПРИМЕНЕНИЕ БЕЛКА PhtX EA023702B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1003920.4A GB201003920D0 (en) 2010-03-09 2010-03-09 Method of treatment
PCT/EP2011/053485 WO2011110570A1 (en) 2010-03-09 2011-03-08 Treatment of streptococcal infections

Publications (2)

Publication Number Publication Date
EA201290689A1 true EA201290689A1 (ru) 2013-08-30
EA023702B1 EA023702B1 (ru) 2016-07-29

Family

ID=42136723

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201290689A EA023702B1 (ru) 2010-03-09 2011-03-08 СПОСОБ ЛЕЧЕНИЯ ИЛИ ПРЕДОТВРАЩЕНИЯ ИНФЕКЦИИ STREPTOCOCCUS PNEUMONIA И ПРИМЕНЕНИЕ БЕЛКА PhtX

Country Status (24)

Country Link
US (2) US20120328659A1 (ru)
EP (1) EP2544711B1 (ru)
JP (1) JP5968229B2 (ru)
KR (1) KR20130038237A (ru)
CN (1) CN102869376A (ru)
AU (1) AU2011226119B2 (ru)
BR (1) BR112012022360A2 (ru)
CA (1) CA2791946A1 (ru)
CY (1) CY1117238T1 (ru)
DK (1) DK2544711T3 (ru)
EA (1) EA023702B1 (ru)
ES (1) ES2562979T3 (ru)
GB (1) GB201003920D0 (ru)
HR (1) HRP20160150T1 (ru)
HU (1) HUE027103T2 (ru)
MX (1) MX2012010386A (ru)
PL (1) PL2544711T3 (ru)
PT (1) PT2544711E (ru)
RS (1) RS54593B1 (ru)
SG (1) SG183474A1 (ru)
SI (1) SI2544711T1 (ru)
SM (1) SMT201600059B (ru)
WO (1) WO2011110570A1 (ru)
ZA (1) ZA201206636B (ru)

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CN105441319A (zh) * 2015-07-29 2016-03-30 东莞东华医院有限公司 一种围产期孕妇b群链球菌采样管及其制备方法
EP3493840B1 (en) 2016-08-05 2022-08-24 Sanofi Pasteur Inc. Multivalent pneumococcal polysaccharide-protein conjugate composition
BR112019001971A2 (pt) 2016-08-05 2019-05-07 Sanofi Pasteur, Inc. composição conjugada de polissacarídeo-proteína pneumocócica multivalente
WO2019152921A1 (en) 2018-02-05 2019-08-08 Sanofi Pasteur Inc. Multivalent pneumococcal polysaccharide-protein conjugate composition
KR102486891B1 (ko) 2018-02-05 2023-01-10 사노피 파스퇴르 인코포레이티드 다가 폐렴구균성 다당류-단백질 접합체 조성물
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Also Published As

Publication number Publication date
EA023702B1 (ru) 2016-07-29
PT2544711E (pt) 2016-03-22
EP2544711B1 (en) 2016-01-06
RS54593B1 (en) 2016-08-31
CY1117238T1 (el) 2017-04-05
WO2011110570A1 (en) 2011-09-15
JP2013521322A (ja) 2013-06-10
SG183474A1 (en) 2012-09-27
ES2562979T3 (es) 2016-03-09
MX2012010386A (es) 2012-10-10
CN102869376A (zh) 2013-01-09
SI2544711T1 (sl) 2016-03-31
BR112012022360A2 (pt) 2019-09-24
HRP20160150T1 (en) 2016-03-11
ZA201206636B (en) 2014-02-26
US20140205634A1 (en) 2014-07-24
US9314518B2 (en) 2016-04-19
HUE027103T2 (en) 2016-08-29
PL2544711T3 (pl) 2016-06-30
GB201003920D0 (en) 2010-04-21
EP2544711A1 (en) 2013-01-16
DK2544711T3 (en) 2016-03-07
AU2011226119A1 (en) 2012-11-01
CA2791946A1 (en) 2011-09-15
US20120328659A1 (en) 2012-12-27
JP5968229B2 (ja) 2016-08-10
SMT201600059B (it) 2016-04-29
KR20130038237A (ko) 2013-04-17
AU2011226119B2 (en) 2014-04-24

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU