EA201491500A1 - Способы лечения фиброза - Google Patents

Способы лечения фиброза

Info

Publication number
EA201491500A1
EA201491500A1 EA201491500A EA201491500A EA201491500A1 EA 201491500 A1 EA201491500 A1 EA 201491500A1 EA 201491500 A EA201491500 A EA 201491500A EA 201491500 A EA201491500 A EA 201491500A EA 201491500 A1 EA201491500 A1 EA 201491500A1
Authority
EA
Eurasian Patent Office
Prior art keywords
fibroza
treatment methods
fibrosis
methods
administering
Prior art date
Application number
EA201491500A
Other languages
English (en)
Other versions
EA030762B1 (ru
Inventor
Серджо Барони
Сальваторе Беллинвия
Франческа Вити
Original Assignee
Ногра Фарма Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ногра Фарма Лимитед filed Critical Ногра Фарма Лимитед
Publication of EA201491500A1 publication Critical patent/EA201491500A1/ru
Publication of EA030762B1 publication Critical patent/EA030762B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/44—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by unsaturated carbon chains
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Abstract

Изобретение направлено на способы лечения фиброза, например фиброза печени и/или фиброза кишечника, включающие введение пациенту, которому это необходимо, эффективного количества соединения по настоящему изобретению.
EA201491500A 2012-02-09 2013-02-08 Способы лечения фиброза EA030762B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12425027 2012-02-09
US201261644544P 2012-05-09 2012-05-09
PCT/EP2013/052617 WO2013117744A2 (en) 2012-02-09 2013-02-08 Methods of treating fibrosis

Publications (2)

Publication Number Publication Date
EA201491500A1 true EA201491500A1 (ru) 2015-01-30
EA030762B1 EA030762B1 (ru) 2018-09-28

Family

ID=48948116

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201491500A EA030762B1 (ru) 2012-02-09 2013-02-08 Способы лечения фиброза

Country Status (12)

Country Link
US (3) US9682923B2 (ru)
EP (2) EP2811993B1 (ru)
JP (2) JP6301844B2 (ru)
KR (1) KR102067848B1 (ru)
CN (3) CN109999017A (ru)
AU (1) AU2013217933B2 (ru)
BR (1) BR112014019399A2 (ru)
CA (1) CA2864059C (ru)
EA (1) EA030762B1 (ru)
IL (3) IL233968A (ru)
MX (1) MX364220B (ru)
WO (1) WO2013117744A2 (ru)

Families Citing this family (10)

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JP2019505598A (ja) * 2016-02-23 2019-02-28 セルジーン アルパイン インベストメント カンパニー Ｉｉ， エルエルシー Ｓｍａｄ７の阻害を用いて、腸線維症を治療する方法
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Also Published As

Publication number Publication date
CA2864059C (en) 2020-04-28
BR112014019399A2 (pt) 2017-07-04
KR20140120936A (ko) 2014-10-14
MX2014009640A (es) 2014-11-12
IL260115A (en) 2018-07-31
IL233968A0 (en) 2014-09-30
US20220033346A1 (en) 2022-02-03
US20180065921A1 (en) 2018-03-08
IL233968A (en) 2017-07-31
WO2013117744A2 (en) 2013-08-15
CN104254327A (zh) 2014-12-31
EP2811993A2 (en) 2014-12-17
JP2017222722A (ja) 2017-12-21
US11046641B2 (en) 2021-06-29
JP2015508068A (ja) 2015-03-16
JP6523399B2 (ja) 2019-05-29
JP6301844B2 (ja) 2018-03-28
AU2013217933A1 (en) 2014-08-21
WO2013117744A9 (en) 2013-10-03
MX364220B (es) 2019-04-16
EP2811993B1 (en) 2019-10-09
IL253421B (en) 2018-07-31
US20150087708A1 (en) 2015-03-26
IL253421A0 (en) 2017-09-28
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US11753365B2 (en) 2023-09-12
CN116602950A (zh) 2023-08-18
CA2864059A1 (en) 2013-08-15
CN109999017A (zh) 2019-07-12
KR102067848B1 (ko) 2020-01-17
EA030762B1 (ru) 2018-09-28
AU2013217933B2 (en) 2017-11-30
WO2013117744A3 (en) 2013-11-21

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