EA201270794A1 - Маркерная вакцина против классической чумы свиней - Google Patents

Маркерная вакцина против классической чумы свиней

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Publication number
EA201270794A1
EA201270794A1 EA201270794A EA201270794A EA201270794A1 EA 201270794 A1 EA201270794 A1 EA 201270794A1 EA 201270794 A EA201270794 A EA 201270794A EA 201270794 A EA201270794 A EA 201270794A EA 201270794 A1 EA201270794 A1 EA 201270794A1
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EA
Eurasian Patent Office
Prior art keywords
swine fever
classical swine
relates
vaccine against
marker
Prior art date
Application number
EA201270794A
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English (en)
Other versions
EA201270794A8 (ru
EA031518B1 (ru
Inventor
Мартин Беер
Сандра Бломе
Иммануэль Ляйфер
Original Assignee
Римзер Арцнаймиттель Аг
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Publication date
Application filed by Римзер Арцнаймиттель Аг filed Critical Римзер Арцнаймиттель Аг
Publication of EA201270794A1 publication Critical patent/EA201270794A1/ru
Publication of EA201270794A8 publication Critical patent/EA201270794A8/ru
Publication of EA031518B1 publication Critical patent/EA031518B1/ru

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    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
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    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
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  • Molecular Biology (AREA)
  • Microbiology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
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  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Изобретение относится к маркерной вакцине для профилактической терапии классической чумы свиней, включающей модифицированный живой аттенуированный вирус классической чумы свиней. Вирусная аминокислотная последовательность TAV-эпитопа Е2 белка включает последовательность, отличную от последовательности вируса дикого типа классической чумы свиней. Изобретение относится к фармацевтическим композициям маркерной вакцины. Изобретение также относится к способу получения маркерных вакцин для профилактики классической чумы свиней с использованием селективной блокады антителами.
EA201270794A 2010-05-18 2011-05-18 Маркерная вакцина против классической чумы свиней EA031518B1 (ru)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
EP10075207 2010-05-18
EP10075206 2010-05-18
DE102010017006 2010-05-18
EP10075205 2010-05-18
EP10075760 2010-12-17
EP10075759 2010-12-17
EP11159207 2011-03-22
PCT/EP2011/002624 WO2011144360A1 (en) 2010-05-18 2011-05-18 Marker vaccine for classical swine fever

Publications (3)

Publication Number Publication Date
EA201270794A1 true EA201270794A1 (ru) 2013-04-30
EA201270794A8 EA201270794A8 (ru) 2017-10-31
EA031518B1 EA031518B1 (ru) 2019-01-31

Family

ID=44461927

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201270794A EA031518B1 (ru) 2010-05-18 2011-05-18 Маркерная вакцина против классической чумы свиней

Country Status (19)

Country Link
US (1) US9315873B2 (ru)
EP (1) EP2571519B1 (ru)
KR (1) KR101845571B1 (ru)
CN (1) CN102905725B (ru)
BR (1) BR112012029145B8 (ru)
CA (1) CA2801897C (ru)
CY (1) CY1118060T1 (ru)
DK (1) DK2571519T3 (ru)
EA (1) EA031518B1 (ru)
ES (1) ES2593965T3 (ru)
HR (1) HRP20161225T1 (ru)
HU (1) HUE029385T2 (ru)
MX (1) MX337048B (ru)
PL (1) PL2571519T3 (ru)
PT (1) PT2571519T (ru)
RS (1) RS55214B1 (ru)
SI (1) SI2571519T1 (ru)
WO (1) WO2011144360A1 (ru)
ZA (1) ZA201208194B (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103159858B (zh) * 2013-02-26 2014-06-04 中国农业科学院上海兽医研究所 猪瘟分支肽及其应用
ES2757927T3 (es) * 2014-05-23 2020-04-30 Boehringer Ingelheim Vetmedica Gmbh Virus de la peste porcina clásica (VPPC) recombinante que comprende sustituciones en el epítopo TAV de la proteína E2

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL184836B1 (pl) * 1994-06-17 2002-12-31 Inst Voor Veehouderij En Dierg Sekwencja nukleotydowa polipeptyd kodowany przez tę sekwencję, szczep szczepionkowy, szczepionka, kompozycja diagnostyczna i sposób odróżniania zwierząt szczepionych
US8846055B2 (en) * 2006-05-30 2014-09-30 The United States Of America, As Represented By The Secretary Of Agriculture Virulence determinant within the E2 structural glycoprotein of classical swine fever virus
US8133495B2 (en) * 2007-05-22 2012-03-13 The United States Of America As Represented By The Secretary Of Agriculture Live attenuated antigenically marked classical swine fever virus
EP2202298A1 (en) 2008-12-23 2010-06-30 Stichting Dienst Landbouwkundig Onderzoek Recombinant classical swine fever virus (CSFV) comprising a modified E2 protein and methods for generating said recombinant CSFV

Also Published As

Publication number Publication date
CA2801897A1 (en) 2011-11-24
BR112012029145B8 (pt) 2022-03-08
HUE029385T2 (en) 2017-02-28
RS55214B1 (sr) 2017-02-28
CY1118060T1 (el) 2017-06-28
PT2571519T (pt) 2016-10-03
MX2012013419A (es) 2013-01-28
KR20130109008A (ko) 2013-10-07
US9315873B2 (en) 2016-04-19
BR112012029145A2 (pt) 2020-07-07
BR112012029145B1 (pt) 2021-09-14
SI2571519T1 (sl) 2017-01-31
EA201270794A8 (ru) 2017-10-31
EP2571519B1 (en) 2016-06-29
ES2593965T3 (es) 2016-12-14
ZA201208194B (en) 2014-01-29
KR101845571B1 (ko) 2018-04-04
HRP20161225T1 (hr) 2016-12-02
MX337048B (es) 2016-02-11
CA2801897C (en) 2019-01-15
CN102905725B (zh) 2016-01-20
CN102905725A (zh) 2013-01-30
EA031518B1 (ru) 2019-01-31
PL2571519T3 (pl) 2017-07-31
WO2011144360A1 (en) 2011-11-24
US20130129762A1 (en) 2013-05-23
DK2571519T3 (en) 2016-10-17
EP2571519A1 (en) 2013-03-27

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