CY1118060T1 - Εμβολιο δεικτης για κλασικη πανωλη των χοιρων - Google Patents

Εμβολιο δεικτης για κλασικη πανωλη των χοιρων

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Publication number
CY1118060T1
CY1118060T1 CY20161100960T CY161100960T CY1118060T1 CY 1118060 T1 CY1118060 T1 CY 1118060T1 CY 20161100960 T CY20161100960 T CY 20161100960T CY 161100960 T CY161100960 T CY 161100960T CY 1118060 T1 CY1118060 T1 CY 1118060T1
Authority
CY
Cyprus
Prior art keywords
classical swine
swine fever
vaccine
prevention
relates
Prior art date
Application number
CY20161100960T
Other languages
English (en)
Inventor
Martin Beer
Sandra Blome
Immanuel Leifer
Original Assignee
Idt Biologika Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idt Biologika Gmbh filed Critical Idt Biologika Gmbh
Publication of CY1118060T1 publication Critical patent/CY1118060T1/el

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/18—Togaviridae; Flaviviridae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Η εφεύρεση αφορά ένα εμβόλιο δείκτη για την προφυλακτική αγωγή της κλασικής πανώλης των χοίρων, το οποίο περιλαμβάνει τροποποιημένο ζωντανό εξασθενημένο κλασικό ιό πανώλης των χοίρων. Η ιική αλληλουχία αμινοξέων του TAV-επιτόπου της πρωτεΐνης Ε2 περιλαμβάνει μία διαφορετική αλληλουχία από αυτήν του αγρίου-τύπου ιού της κλασικής πανώλης των χοίρων. Η εφεύρεση αφορά φαρμακευτικές συνθέσεις του εμβολίου δείκτη. Η εφεύρεση αφορά επίσης μία μέθοδο παραγωγής εμβολίων δεικτών για την πρόληψη της κλασικής πανώλης των χοίρων, με τη χρήση επιλεκτικής πίεσης αντισώματος.
CY20161100960T 2010-05-18 2016-09-27 Εμβολιο δεικτης για κλασικη πανωλη των χοιρων CY1118060T1 (el)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP10075205 2010-05-18
EP10075206 2010-05-18
EP10075207 2010-05-18
DE102010017006 2010-05-18
EP10075760 2010-12-17
EP10075759 2010-12-17
EP11159207 2011-03-22
EP11724548.0A EP2571519B1 (en) 2010-05-18 2011-05-18 Marker vaccine for classical swine fever
PCT/EP2011/002624 WO2011144360A1 (en) 2010-05-18 2011-05-18 Marker vaccine for classical swine fever

Publications (1)

Publication Number Publication Date
CY1118060T1 true CY1118060T1 (el) 2017-06-28

Family

ID=44461927

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161100960T CY1118060T1 (el) 2010-05-18 2016-09-27 Εμβολιο δεικτης για κλασικη πανωλη των χοιρων

Country Status (19)

Country Link
US (1) US9315873B2 (el)
EP (1) EP2571519B1 (el)
KR (1) KR101845571B1 (el)
CN (1) CN102905725B (el)
BR (1) BR112012029145B8 (el)
CA (1) CA2801897C (el)
CY (1) CY1118060T1 (el)
DK (1) DK2571519T3 (el)
EA (1) EA031518B1 (el)
ES (1) ES2593965T3 (el)
HR (1) HRP20161225T1 (el)
HU (1) HUE029385T2 (el)
MX (1) MX337048B (el)
PL (1) PL2571519T3 (el)
PT (1) PT2571519T (el)
RS (1) RS55214B1 (el)
SI (1) SI2571519T1 (el)
WO (1) WO2011144360A1 (el)
ZA (1) ZA201208194B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103159858B (zh) * 2013-02-26 2014-06-04 中国农业科学院上海兽医研究所 猪瘟分支肽及其应用
US9993544B2 (en) 2014-05-23 2018-06-12 Boehringer Ingelheim Vetmedica Gmbh Recombinant classical swine fever virus (CSFV) comprising substitution in the TAV epitope of the E2 protein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0766740A1 (en) * 1994-06-17 1997-04-09 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Nucleotide sequences of pestivirus strains, polypeptides encoded by these sequences and use thereof for diagnosis and prevention of pestivirus infections
US8846055B2 (en) 2006-05-30 2014-09-30 The United States Of America, As Represented By The Secretary Of Agriculture Virulence determinant within the E2 structural glycoprotein of classical swine fever virus
US8133495B2 (en) * 2007-05-22 2012-03-13 The United States Of America As Represented By The Secretary Of Agriculture Live attenuated antigenically marked classical swine fever virus
EP2202298A1 (en) * 2008-12-23 2010-06-30 Stichting Dienst Landbouwkundig Onderzoek Recombinant classical swine fever virus (CSFV) comprising a modified E2 protein and methods for generating said recombinant CSFV

Also Published As

Publication number Publication date
KR101845571B1 (ko) 2018-04-04
EP2571519A1 (en) 2013-03-27
MX337048B (es) 2016-02-11
PL2571519T3 (pl) 2017-07-31
CA2801897A1 (en) 2011-11-24
US20130129762A1 (en) 2013-05-23
EA031518B1 (ru) 2019-01-31
ES2593965T3 (es) 2016-12-14
EA201270794A1 (ru) 2013-04-30
HRP20161225T1 (hr) 2016-12-02
BR112012029145A2 (pt) 2020-07-07
MX2012013419A (es) 2013-01-28
CN102905725A (zh) 2013-01-30
DK2571519T3 (en) 2016-10-17
US9315873B2 (en) 2016-04-19
CN102905725B (zh) 2016-01-20
ZA201208194B (en) 2014-01-29
CA2801897C (en) 2019-01-15
WO2011144360A1 (en) 2011-11-24
BR112012029145B8 (pt) 2022-03-08
HUE029385T2 (en) 2017-02-28
EA201270794A8 (ru) 2017-10-31
EP2571519B1 (en) 2016-06-29
KR20130109008A (ko) 2013-10-07
PT2571519T (pt) 2016-10-03
RS55214B1 (sr) 2017-02-28
BR112012029145B1 (pt) 2021-09-14
SI2571519T1 (sl) 2017-01-31

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