EA201071112A1 - ПРОИЗВОДНЫЕ ПОЛИЗАМЕЩЁННЫХ 2-АРИЛ-6-ФЕНИЛИМИДАЗО[1,2-a]ПИРИДИНОВ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ ИХ В ТЕРАПИИ - Google Patents

ПРОИЗВОДНЫЕ ПОЛИЗАМЕЩЁННЫХ 2-АРИЛ-6-ФЕНИЛИМИДАЗО[1,2-a]ПИРИДИНОВ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ ИХ В ТЕРАПИИ

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EA201071112A1
EA201071112A1 EA201071112A EA201071112A EA201071112A1 EA 201071112 A1 EA201071112 A1 EA 201071112A1 EA 201071112 A EA201071112 A EA 201071112A EA 201071112 A EA201071112 A EA 201071112A EA 201071112 A1 EA201071112 A1 EA 201071112A1
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optionally substituted
pyridine
therapy
alkyl
substituents
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EA201071112A
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Антонио Альмарио Гарсия
Даниэлль Де Перетти
Янник Эванно
Патрик Ларденуа
Андре Маланда
Натали Ракотоарисоа
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Санофи-Авентис
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Publication of EA201071112A1 publication Critical patent/EA201071112A1/ru

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Abstract

Изобретение относится к соединениям формулы (I)в которой Rобозначает фенильную или нафтильную группу, причем эти две группы необязательно могут быть замещены; Х обозначает от 1 до 4 заместителей, одинаковых или отличающихся друг от друга, выбираемых из водорода, галогена, (C-С)алкила, галоген(C-С)алкила, (C-С)алкокси, NRaRb, циано, нитро; R обозначает в положении 3, 5, 7, 8 имидазо[1,2-а]пиридина от 1 до 4 заместителя, одинаковые или отличающиеся друг от друга; Rи Rобозначают, независимо один от другого, атом водорода, необязательно замещенную (C-С)алкильную группу; необязательно замещенную арильную группу; Rи Х могут образовывать вместе с атомами углерода, которые их несут, углеродный цикл из 5-7 атомов углерода; Rобозначает атом водорода, (C-С)алкильную группу, необязательно замещенную, или арильную группу, необязательно замещенную одним или несколькими заместителями. Изобретение относится к применению соединений в терапии и к способу их получения.
EA201071112A 2008-03-21 2009-03-20 ПРОИЗВОДНЫЕ ПОЛИЗАМЕЩЁННЫХ 2-АРИЛ-6-ФЕНИЛИМИДАЗО[1,2-a]ПИРИДИНОВ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ ИХ В ТЕРАПИИ EA201071112A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0801581A FR2928922B1 (fr) 2008-03-21 2008-03-21 Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique
PCT/FR2009/000302 WO2009144394A1 (fr) 2008-03-21 2009-03-20 Derives de 2-aryl-6-phenyl-imidazo[1,2-a]pyridines polysubstitues, leur préparation et leur application en thérapeutique

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EA201071112A1 true EA201071112A1 (ru) 2011-04-29

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US (1) US8507520B2 (ru)
EP (1) EP2262769B1 (ru)
JP (1) JP5508385B2 (ru)
KR (1) KR20100129775A (ru)
CN (2) CN102036959B (ru)
AR (1) AR070993A1 (ru)
AU (1) AU2009253234B2 (ru)
BR (1) BRPI0909415A2 (ru)
CA (1) CA2719125C (ru)
CL (1) CL2009000696A1 (ru)
CO (1) CO6290657A2 (ru)
EA (1) EA201071112A1 (ru)
FR (1) FR2928922B1 (ru)
IL (1) IL208246A0 (ru)
MA (1) MA32247B1 (ru)
ME (1) ME01029B (ru)
MX (1) MX2010010316A (ru)
NZ (1) NZ588151A (ru)
SG (1) SG189679A1 (ru)
TW (1) TW200944202A (ru)
UY (1) UY31728A (ru)
WO (1) WO2009144394A1 (ru)
ZA (1) ZA201006728B (ru)

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JP2011515382A (ja) 2011-05-19
AU2009253234B2 (en) 2013-07-11
TW200944202A (en) 2009-11-01
AU2009253234A1 (en) 2009-12-03
MX2010010316A (es) 2010-12-14
FR2928922A1 (fr) 2009-09-25
CN102036959A (zh) 2011-04-27
ME01029B (me) 2012-10-20
CA2719125A1 (fr) 2009-12-03
ZA201006728B (en) 2011-11-30
CA2719125C (fr) 2016-07-26
MA32247B1 (fr) 2011-04-01
CN103193815A (zh) 2013-07-10
JP5508385B2 (ja) 2014-05-28
CN102036959B (zh) 2013-05-22
BRPI0909415A2 (pt) 2019-01-15
IL208246A0 (en) 2010-12-30
EP2262769B1 (fr) 2014-11-05
SG189679A1 (en) 2013-05-31
US8507520B2 (en) 2013-08-13
KR20100129775A (ko) 2010-12-09
US20110065745A1 (en) 2011-03-17
FR2928922B1 (fr) 2010-04-23
WO2009144394A8 (fr) 2010-10-14
WO2009144394A1 (fr) 2009-12-03
NZ588151A (en) 2012-07-27
AR070993A1 (es) 2010-05-19
CO6290657A2 (es) 2011-06-20
CL2009000696A1 (es) 2010-08-13
UY31728A (es) 2009-11-10

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