EA201001238A1 - Соединения и композиции в качестве ингибиторов киназы - Google Patents

Соединения и композиции в качестве ингибиторов киназы

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Publication number
EA201001238A1
EA201001238A1 EA201001238A EA201001238A EA201001238A1 EA 201001238 A1 EA201001238 A1 EA 201001238A1 EA 201001238 A EA201001238 A EA 201001238A EA 201001238 A EA201001238 A EA 201001238A EA 201001238 A1 EA201001238 A1 EA 201001238A1
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Eurasian Patent Office
Prior art keywords
compounds
compositions
kinase inhibitors
fms
misregulated
Prior art date
Application number
EA201001238A
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English (en)
Inventor
Барун Окрам
Тетсуо Уно
Цян Дин
Яхуа Лю
Юньхо Цзинь
Цисюй Цзинь
Сюй Ву
Цзяньвэй Чэ
С. Франк Янь
Сюэши Хао
Original Assignee
Айрм Ллк
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Application filed by Айрм Ллк filed Critical Айрм Ллк
Publication of EA201001238A1 publication Critical patent/EA201001238A1/ru

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61P17/04—Antipruritics
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  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

В заявке описан новый класс производных 2,7-нафтиридина формулыв которой группы R-R, Rопределены в формуле изобретения; фармацевтические композиции, включающие такие соединения, и способы применения таких соединений для лечения или профилактики заболевания или расстройства, связанных с неправильной или разрегулированной активностью киназы, особенно Syk, ZAP70, KDR, FMS, FLT*, c-Kit, RET, TrkA, TrkB, TrkC-GR-1R, Alk, c-FMS или их комбинации.
EA201001238A 2008-02-01 2009-01-27 Соединения и композиции в качестве ингибиторов киназы EA201001238A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2566508P 2008-02-01 2008-02-01
US5309108P 2008-05-14 2008-05-14
PCT/US2009/032148 WO2009097287A1 (en) 2008-02-01 2009-01-27 Compounds and compositions as kinase inhibitors

Publications (1)

Publication Number Publication Date
EA201001238A1 true EA201001238A1 (ru) 2011-04-29

Family

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Family Applications (2)

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EA201001236A EA201001236A1 (ru) 2008-02-01 2009-01-27 Производные пиридо[4,3-d]пиримидинона в качестве ингибиторов киназ
EA201001238A EA201001238A1 (ru) 2008-02-01 2009-01-27 Соединения и композиции в качестве ингибиторов киназы

Family Applications Before (1)

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EA201001236A EA201001236A1 (ru) 2008-02-01 2009-01-27 Производные пиридо[4,3-d]пиримидинона в качестве ингибиторов киназ

Country Status (17)

Country Link
US (2) US8354526B2 (ru)
EP (2) EP2250169A1 (ru)
JP (2) JP2011510990A (ru)
KR (2) KR20100118989A (ru)
CN (2) CN101983198A (ru)
AR (2) AR070521A1 (ru)
AU (2) AU2009210517B2 (ru)
BR (1) BRPI0906973A2 (ru)
CA (2) CA2711937A1 (ru)
CL (1) CL2009000200A1 (ru)
EA (2) EA201001236A1 (ru)
MX (2) MX2010008418A (ru)
PA (2) PA8814301A1 (ru)
PE (2) PE20091408A1 (ru)
TW (2) TW200938542A (ru)
UY (2) UY31623A1 (ru)
WO (2) WO2009097287A1 (ru)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2719367C2 (ru) * 2015-06-18 2020-04-17 Корея Рисерч Инститьют Оф Кемикал Текнолоджи Гетероарильное производное или его фармацевтически приемлемая соль, способ их получения и фармацевтическая композиция для профилактики или лечения заболеваний, связанных с pi3 киназами, содержащая данное действующее вещество

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