EA200801967A1 - Дозированная лекарственная форма на основе циклогексанового полиола (варианты), способ ее получения, способ лечения болезни альцгеймера с ее помощью и циклогексановый полиол в качестве средства при изготовлении лекарственного средства - Google Patents

Дозированная лекарственная форма на основе циклогексанового полиола (варианты), способ ее получения, способ лечения болезни альцгеймера с ее помощью и циклогексановый полиол в качестве средства при изготовлении лекарственного средства

Info

Publication number
EA200801967A1
EA200801967A1 EA200801967A EA200801967A EA200801967A1 EA 200801967 A1 EA200801967 A1 EA 200801967A1 EA 200801967 A EA200801967 A EA 200801967A EA 200801967 A EA200801967 A EA 200801967A EA 200801967 A1 EA200801967 A1 EA 200801967A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
cyclogexane
dosage form
disease
polyous
Prior art date
Application number
EA200801967A
Other languages
English (en)
Russian (ru)
Inventor
Антонио Крус
Джоанн Маклорин
Original Assignee
Ворэта Фармэсьютиклз Инк.
Джоанн Маклорин
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ворэта Фармэсьютиклз Инк., Джоанн Маклорин filed Critical Ворэта Фармэсьютиклз Инк.
Publication of EA200801967A1 publication Critical patent/EA200801967A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EA200801967A 2006-03-09 2007-03-09 Дозированная лекарственная форма на основе циклогексанового полиола (варианты), способ ее получения, способ лечения болезни альцгеймера с ее помощью и циклогексановый полиол в качестве средства при изготовлении лекарственного средства EA200801967A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78052606P 2006-03-09 2006-03-09
US81986406P 2006-07-11 2006-07-11
US89766707P 2007-01-26 2007-01-26
PCT/CA2007/000395 WO2007101353A1 (en) 2006-03-09 2007-03-09 A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation

Publications (1)

Publication Number Publication Date
EA200801967A1 true EA200801967A1 (ru) 2009-04-28

Family

ID=38474578

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200801967A EA200801967A1 (ru) 2006-03-09 2007-03-09 Дозированная лекарственная форма на основе циклогексанового полиола (варианты), способ ее получения, способ лечения болезни альцгеймера с ее помощью и циклогексановый полиол в качестве средства при изготовлении лекарственного средства

Country Status (14)

Country Link
US (1) US20100113613A1 (enExample)
EP (1) EP1996175A4 (enExample)
JP (1) JP2009529502A (enExample)
KR (1) KR20090026247A (enExample)
CN (1) CN103054837A (enExample)
AU (1) AU2007222864A1 (enExample)
BR (1) BRPI0708725A2 (enExample)
CA (1) CA2644804A1 (enExample)
EA (1) EA200801967A1 (enExample)
IL (1) IL193970A0 (enExample)
MX (1) MX2008011553A (enExample)
NZ (1) NZ571181A (enExample)
WO (1) WO2007101353A1 (enExample)
ZA (1) ZA200908303B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7521481B2 (en) 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
US20100173960A1 (en) * 2006-09-21 2010-07-08 Antonio Cruz The Combination of a Cyclohexanehexol and a NSAID for the Treatment of Neurodegenerative Diseases
CA2670405A1 (en) * 2006-11-24 2008-05-29 Waratah Pharmaceuticals Inc. Combination treatments for alzheimer's disease and related neurodegenerative diseases
DE102007030695A1 (de) * 2007-07-01 2009-01-08 Sciconcept Gmbh Co-Kristalle aus Harnstoff mit Amid- und/oder Harnstoffderivaten
US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
EP2714050A1 (en) * 2011-06-03 2014-04-09 Elan Pharmaceuticals, Inc. Scyllo-inositol for the treatment of behavioral and psychiatric disorders
EP3563849A3 (en) 2012-10-25 2020-02-12 The General Hospital Corporation Combination therapies for the treatment of alzheimer's disease and related disorders
US10058530B2 (en) 2012-10-25 2018-08-28 The General Hospital Corporation Combination therapies for the treatment of Alzheimer's disease and related disorders
EP2964249A1 (en) * 2013-03-06 2016-01-13 Acorda Therapeutics, Inc. Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure
US10525005B2 (en) 2013-05-23 2020-01-07 The General Hospital Corporation Cromolyn compositions and methods thereof
CN110305095A (zh) 2013-10-22 2019-10-08 综合医院公司 色甘酸衍生物以及成像和治疗的相关方法
KR20190044647A (ko) 2016-08-31 2019-04-30 더 제너럴 하스피탈 코포레이션 신경변성 질환과 관련된 신경-염증에서 대식세포/미세아교세포
CN111565711B (zh) 2017-07-20 2023-01-03 阿茨治疗股份有限公司 色甘酸钠和布洛芬的粉末化制剂
CA3105392A1 (en) 2018-07-02 2020-01-09 The General Hospital Corporation Powdered formulations of cromolyn sodium and .alpha.-lactose
WO2020074944A1 (en) 2018-10-11 2020-04-16 Sanifit Therapeutics S.A. Inositol phosphates for the treatment of ectopic calcification
WO2020123449A1 (en) 2018-12-10 2020-06-18 The General Hospital Corporation Cromolyn esters and uses thereof
EP4132507A4 (en) 2020-04-06 2024-05-15 The General Hospital Corporation METHODS FOR TREATING CORONAVIRUS-INDUCED INFLAMMATORY CONDITIONS

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4454151A (en) * 1982-03-22 1984-06-12 Syntex (U.S.A.) Inc. Use of pyrrolo pyrroles in treatment of ophthalmic diseases
US4515722A (en) * 1982-03-30 1985-05-07 Merck & Co., Inc. Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents
US4474806A (en) * 1982-05-10 1984-10-02 Merck & Co., Inc. Sulfonyl or carbonyl inositol derivatives useful as anti-inflammatory/analgesic agents
US4952396A (en) * 1986-11-19 1990-08-28 Linus Pauling Institute Of Science & Medicine Method of using phytic acid for inhibiting tumor growth
US4758430A (en) * 1987-01-21 1988-07-19 Robert Sabin Method of treatment of Alzheimer's disease using phytic acid
US4847082A (en) * 1987-01-21 1989-07-11 Robert Sabin Method of treatment of Alzheimer's disease using phytic acid
SE8904355D0 (sv) * 1989-12-21 1989-12-21 Perstorp Ab Medicament
US5217959A (en) * 1990-09-06 1993-06-08 Robert Sabin Method of treating multiple sclerosis with phytic acid
US5112814A (en) * 1990-10-24 1992-05-12 Robert Sabin Method of treatment of Parkinson's disease using phytic acid
KR0185215B1 (ko) * 1990-11-30 1999-05-01 요시다 쇼오지 서방성 안구삽입용 약제
SE9102068L (sv) * 1991-07-03 1993-01-04 Perstorp Ab Derivat av inositol, kompositioner innehaallande dessa samt anvaendning daerav
SE469260B (sv) * 1992-02-25 1993-06-14 Perstorp Ab En farmaceutisk komposition med foerbaettrad biotillgaenglighet avseende inositolfosfat
CA2146353C (en) * 1992-10-05 2007-04-17 Tomas Hudlicky Syntheses of d-chiro-3-inosose and (+)-d-chiro-inositol
US5840294A (en) * 1993-03-29 1998-11-24 Queen's University At Kingston Method for treating amyloidosis
US5643562A (en) * 1993-03-29 1997-07-01 Queen's University Of Kingston Method for treating amyloidosis
US5972328A (en) * 1993-03-29 1999-10-26 Queen's University At Kingston Method for treating amyloidosis
DE69333071T2 (de) * 1993-04-05 2004-05-06 Aveve N.V. Phytate-Hydrolyse und enzymatische Zusammensetzung für die Hydrolyse von Phytat
DE69416594T2 (de) * 1993-08-11 1999-09-23 Hokko Chemical Industry Co. Ltd., Tokio/Tokyo Verfahren zur herstellung von d-chiro inositol
SE502574C2 (sv) * 1994-01-25 1995-11-13 Perstorp Ab En farmaceutisk komposition med förbättrad biotillgänglighet hos inositolfosfat
US5858326A (en) * 1995-06-06 1999-01-12 Neurochem, Inc. Methods of increasing amyloid deposition
US5756541A (en) * 1996-03-11 1998-05-26 Qlt Phototherapeutics Inc Vision through photodynamic therapy of the eye
US6232486B1 (en) * 1996-06-11 2001-05-15 Nutrimed Biotech Molecular probes and modulators for PI-PLC and PI 3-kinase
US5977078A (en) * 1996-09-20 1999-11-02 The Regents Of The Univesity Of California Inositol polyphosphate derivatives and methods of using same
US5880099A (en) * 1996-09-20 1999-03-09 The Regents Of The University Of California Inositol polyphosphates and methods of using same
US5998485A (en) * 1997-06-16 1999-12-07 Cedars-Sinai Medical Center Method for modulating immune response with inositol
US6153603A (en) * 1997-06-27 2000-11-28 Perstorp Ab Method of treating angiogenesis in tumor tissue
US6310073B1 (en) * 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
US6818430B1 (en) * 1999-06-07 2004-11-16 Hokko Chemical Industry Co., Ltd. Process for producing L-epi-2-inosose and novel process for producing epi-inositol
US6329256B1 (en) * 1999-09-24 2001-12-11 Advanced Micro Devices, Inc. Self-aligned damascene gate formation with low gate resistance
CZ20021346A3 (cs) * 1999-10-18 2003-06-18 Muscletech Research And Development Inc. Potravinový doplněk pro růst svalové hmoty a síly
US6331313B1 (en) * 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
DE10031955A1 (de) * 2000-06-30 2002-01-17 Deutsches Krebsforsch Curcumin-Derivate mit gegenüber Curcumin verbesserter Wasserlöslichkeit und diese enthaltende Arzneimittel
US8034803B2 (en) * 2001-02-06 2011-10-11 Qlt Inc. Photodynamic therapy of occult age-related macular degeneration
US7060695B2 (en) * 2001-02-06 2006-06-13 Qlt, Inc. Method to prevent vision loss
US20030181531A1 (en) * 2003-02-11 2003-09-25 David Sherris Compositions and methods of administering tubulin binding agents for the treatment of ocular diseases
WO2003007944A1 (en) * 2001-07-20 2003-01-30 Qlt, Inc. Treatment of macular edema with photodynamic therapy
US20040058313A1 (en) * 2002-04-24 2004-03-25 Abreu Marcio Marc Compositions, targets, methods and devices for the therapy of ocular and periocular disorders
US7521481B2 (en) * 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
JP4526485B2 (ja) * 2003-10-14 2010-08-18 北興化学工業株式会社 シロ−イノシトールの製造方法
MX2007005870A (es) * 2004-11-17 2007-10-10 Joanne Mclauring Composiciones que comprenden derivados de escilo-inositol y metodos para tratar trastornos de agregacion de proteinas.

Also Published As

Publication number Publication date
MX2008011553A (es) 2008-12-09
AU2007222864A1 (en) 2007-09-13
JP2009529502A (ja) 2009-08-20
KR20090026247A (ko) 2009-03-12
BRPI0708725A2 (pt) 2011-06-07
CN103054837A (zh) 2013-04-24
ZA200908303B (en) 2012-08-29
CA2644804A1 (en) 2007-09-13
NZ571181A (en) 2011-12-22
IL193970A0 (en) 2009-08-03
EP1996175A4 (en) 2009-06-10
US20100113613A1 (en) 2010-05-06
EP1996175A1 (en) 2008-12-03
AU2007222864A8 (en) 2010-06-10
WO2007101353A1 (en) 2007-09-13

Similar Documents

Publication Publication Date Title
EA200801967A1 (ru) Дозированная лекарственная форма на основе циклогексанового полиола (варианты), способ ее получения, способ лечения болезни альцгеймера с ее помощью и циклогексановый полиол в качестве средства при изготовлении лекарственного средства
JP2009529502A5 (enExample)
US20220304995A1 (en) Ophthalmic compositions
US20170290797A1 (en) Combination therapies for the treatment of alzheimer's disease and related disorders
CN106068123B (zh) 二丁基羟基甲苯的稳定化方法
JP2022547604A (ja) 過度の眠気の治療のためのオレキシン２受容体アゴニストの使用
RS61053B1 (sr) Pоstupak za sprečavanje i / ili lečenje kognitivnog oštećenja povezanog sa starenjem i neuroinflamacijom
IL318427A (en) Varenicline compound for use as a medication for treating dry eye, increasing tear production and treating eye discomfort and a pramipexole preparation containing varenicline
KR101312740B1 (ko) 안구 내 이행성 촉진 수성 점안제
HRP20110250T1 (hr) Optimalizacija liječenja philadelphia-pozitivne leukemije s imatinibom inhibitorom abl-tirozin kinaze
WO2016171152A1 (ja) 角膜障害の治療剤、改善剤または予防剤
RU2020123405A (ru) Лекарственная композиция для профилактики или лечения вторичного гиперпаратиреоза при поддерживающем диализе
EP2380574A1 (en) Eslicarbazepine acetate and methods of use
CN106068122A (zh) 二丁基羟基甲苯的稳定化方法
MX2007013882A (es) Metodos para preparar composiciones farmaceuticas que comprenden acetato de eslicarbazepina y metodos de uso.
EP2952189B1 (en) Clear aqueous solution
TWI713618B (zh) 外用劑
AU2003257589A1 (en) Remedy for integration dysfunction syndrome
JP2017505350A (ja) 硫黄含有部分を含む糖誘導体ならびにその作製方法およびｍｐｓ ｉｉｉｃの処置のためのその使用方法
JPWO2017022787A1 (ja) 収縮力低下随伴性排尿筋過活動改善剤
US11185517B2 (en) Pharmaceutical composition for treatment or remission of chronic myelogenous leukemia
Wong et al. Optimal haloperidol dosage for first episode schizophrenia
HK1202451A1 (en) Therapeutic compositions for intranasal administration of zolpidem
US20240316143A1 (en) Therapeutic agents and/or pharmaceutical compositions for neurocognitive disorders
Kapur et al. What is the lowest effective dose of haloperidol? Evidence from PET studies