KR20090026247A - 단백질 응집 장애의 치료를 위한 사이클로헥산 폴리알콜 제형 - Google Patents
단백질 응집 장애의 치료를 위한 사이클로헥산 폴리알콜 제형 Download PDFInfo
- Publication number
- KR20090026247A KR20090026247A KR1020087024122A KR20087024122A KR20090026247A KR 20090026247 A KR20090026247 A KR 20090026247A KR 1020087024122 A KR1020087024122 A KR 1020087024122A KR 20087024122 A KR20087024122 A KR 20087024122A KR 20090026247 A KR20090026247 A KR 20090026247A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- dosage form
- cyclohexane polyalcohol
- alkyl
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 150000005846 sugar alcohols Polymers 0.000 title claims abstract description 288
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 title claims abstract description 277
- 239000000203 mixture Substances 0.000 title claims abstract description 124
- 238000009472 formulation Methods 0.000 title claims abstract description 100
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- 238000011282 treatment Methods 0.000 title abstract description 52
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- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 description 76
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- CDAISMWEOUEBRE-UHFFFAOYSA-N inositol Chemical compound OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 49
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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| US5756541A (en) * | 1996-03-11 | 1998-05-26 | Qlt Phototherapeutics Inc | Vision through photodynamic therapy of the eye |
| US6232486B1 (en) * | 1996-06-11 | 2001-05-15 | Nutrimed Biotech | Molecular probes and modulators for PI-PLC and PI 3-kinase |
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-
2007
- 2007-03-09 EA EA200801967A patent/EA200801967A1/ru unknown
- 2007-03-09 AU AU2007222864A patent/AU2007222864A1/en not_active Abandoned
- 2007-03-09 CA CA002644804A patent/CA2644804A1/en not_active Abandoned
- 2007-03-09 WO PCT/CA2007/000395 patent/WO2007101353A1/en not_active Ceased
- 2007-03-09 US US12/282,030 patent/US20100113613A1/en not_active Abandoned
- 2007-03-09 MX MX2008011553A patent/MX2008011553A/es not_active Application Discontinuation
- 2007-03-09 JP JP2008557568A patent/JP2009529502A/ja active Pending
- 2007-03-09 KR KR1020087024122A patent/KR20090026247A/ko not_active Ceased
- 2007-03-09 BR BRPI0708725-0A patent/BRPI0708725A2/pt not_active IP Right Cessation
- 2007-03-09 EP EP07710726A patent/EP1996175A4/en not_active Withdrawn
- 2007-03-09 CN CN201210257027XA patent/CN103054837A/zh active Pending
- 2007-03-09 NZ NZ571181A patent/NZ571181A/en not_active IP Right Cessation
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2008
- 2008-09-08 IL IL193970A patent/IL193970A0/en unknown
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2009
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Also Published As
| Publication number | Publication date |
|---|---|
| MX2008011553A (es) | 2008-12-09 |
| JP2009529502A (ja) | 2009-08-20 |
| CA2644804A1 (en) | 2007-09-13 |
| CN103054837A (zh) | 2013-04-24 |
| NZ571181A (en) | 2011-12-22 |
| AU2007222864A8 (en) | 2010-06-10 |
| ZA200908303B (en) | 2012-08-29 |
| WO2007101353A1 (en) | 2007-09-13 |
| AU2007222864A1 (en) | 2007-09-13 |
| EP1996175A1 (en) | 2008-12-03 |
| BRPI0708725A2 (pt) | 2011-06-07 |
| EA200801967A1 (ru) | 2009-04-28 |
| IL193970A0 (en) | 2009-08-03 |
| US20100113613A1 (en) | 2010-05-06 |
| EP1996175A4 (en) | 2009-06-10 |
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