ZA200908303B - A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation - Google Patents
A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregationInfo
- Publication number
- ZA200908303B ZA200908303B ZA2009/08303A ZA200908303A ZA200908303B ZA 200908303 B ZA200908303 B ZA 200908303B ZA 2009/08303 A ZA2009/08303 A ZA 2009/08303A ZA 200908303 A ZA200908303 A ZA 200908303A ZA 200908303 B ZA200908303 B ZA 200908303B
- Authority
- ZA
- South Africa
- Prior art keywords
- disorders
- treatment
- protein aggregation
- cyclohexane polyalcohol
- polyalcohol formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78052606P | 2006-03-09 | 2006-03-09 | |
| US81986406P | 2006-07-11 | 2006-07-11 | |
| US89766707P | 2007-01-26 | 2007-01-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200908303B true ZA200908303B (en) | 2012-08-29 |
Family
ID=38474578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2009/08303A ZA200908303B (en) | 2006-03-09 | 2009-11-24 | A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20100113613A1 (enExample) |
| EP (1) | EP1996175A4 (enExample) |
| JP (1) | JP2009529502A (enExample) |
| KR (1) | KR20090026247A (enExample) |
| CN (1) | CN103054837A (enExample) |
| AU (1) | AU2007222864A1 (enExample) |
| BR (1) | BRPI0708725A2 (enExample) |
| CA (1) | CA2644804A1 (enExample) |
| EA (1) | EA200801967A1 (enExample) |
| IL (1) | IL193970A0 (enExample) |
| MX (1) | MX2008011553A (enExample) |
| NZ (1) | NZ571181A (enExample) |
| WO (1) | WO2007101353A1 (enExample) |
| ZA (1) | ZA200908303B (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7521481B2 (en) | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
| WO2008034244A1 (en) * | 2006-09-21 | 2008-03-27 | Waratah Pharmaceuticals Inc. | The combination of a cyclohexanehexol and a nsaid for the treatment of neurodegenerative diseases |
| WO2008061373A1 (en) * | 2006-11-24 | 2008-05-29 | Waratah Pharmaceuticals Inc. | Combination treatments for alzheimer's disease and similar diseases |
| DE102007030695A1 (de) * | 2007-07-01 | 2009-01-08 | Sciconcept Gmbh | Co-Kristalle aus Harnstoff mit Amid- und/oder Harnstoffderivaten |
| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| CA2837926A1 (en) * | 2011-06-03 | 2012-12-20 | Susan ABUSHAKRA | Scyllo - inositol for the treatment of behavioral and psychiatric disorders |
| US9855276B2 (en) | 2012-10-25 | 2018-01-02 | The General Hospital Corporation | Combination therapies for the treatment of Alzheimer's disease and related disorders |
| US10058530B2 (en) | 2012-10-25 | 2018-08-28 | The General Hospital Corporation | Combination therapies for the treatment of Alzheimer's disease and related disorders |
| US20160129084A1 (en) * | 2013-03-06 | 2016-05-12 | Acorda Therapeutics, Inc. | Therapeutic Dosing of a Neuregulin or a Fragment Thereof for Treatment or Prophylaxis of Heart Failure |
| US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
| AU2014340182B2 (en) | 2013-10-22 | 2019-05-23 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| EP3506894B1 (en) | 2016-08-31 | 2023-08-23 | The General Hospital Corporation | Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases |
| WO2019017995A1 (en) | 2017-07-20 | 2019-01-24 | Aztherapies, Inc. | FORMULATIONS OF CROMOLYNE SODIUM POWDER AND IBUPROFEN |
| JP2021529771A (ja) | 2018-07-02 | 2021-11-04 | ザ ジェネラル ホスピタル コーポレイション | クロモリンナトリウムおよびα−ラクトースの粉末製剤 |
| CN112839661A (zh) | 2018-10-11 | 2021-05-25 | 萨尼菲特治疗有限公司 | 用于治疗异位钙化的肌醇磷酸酯类 |
| US12383528B2 (en) | 2018-12-10 | 2025-08-12 | The General Hospital Corporation | Cromolyn esters and uses thereof |
| JP2023520580A (ja) | 2020-04-06 | 2023-05-17 | ザ ジェネラル ホスピタル コーポレイション | コロナウイルス誘発炎症状態の処置方法 |
| WO2022146914A1 (en) | 2020-12-28 | 2022-07-07 | The General Hospital Corporation | Cromolyn derivatives and uses thereof |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4454151A (en) * | 1982-03-22 | 1984-06-12 | Syntex (U.S.A.) Inc. | Use of pyrrolo pyrroles in treatment of ophthalmic diseases |
| US4515722A (en) * | 1982-03-30 | 1985-05-07 | Merck & Co., Inc. | Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents |
| US4474806A (en) * | 1982-05-10 | 1984-10-02 | Merck & Co., Inc. | Sulfonyl or carbonyl inositol derivatives useful as anti-inflammatory/analgesic agents |
| US4952396A (en) * | 1986-11-19 | 1990-08-28 | Linus Pauling Institute Of Science & Medicine | Method of using phytic acid for inhibiting tumor growth |
| US4847082A (en) * | 1987-01-21 | 1989-07-11 | Robert Sabin | Method of treatment of Alzheimer's disease using phytic acid |
| US4758430A (en) * | 1987-01-21 | 1988-07-19 | Robert Sabin | Method of treatment of Alzheimer's disease using phytic acid |
| SE8904355D0 (sv) * | 1989-12-21 | 1989-12-21 | Perstorp Ab | Medicament |
| US5217959A (en) * | 1990-09-06 | 1993-06-08 | Robert Sabin | Method of treating multiple sclerosis with phytic acid |
| US5112814A (en) * | 1990-10-24 | 1992-05-12 | Robert Sabin | Method of treatment of Parkinson's disease using phytic acid |
| KR0185215B1 (ko) * | 1990-11-30 | 1999-05-01 | 요시다 쇼오지 | 서방성 안구삽입용 약제 |
| SE9102068L (sv) * | 1991-07-03 | 1993-01-04 | Perstorp Ab | Derivat av inositol, kompositioner innehaallande dessa samt anvaendning daerav |
| SE9200547L (sv) * | 1992-02-25 | 1993-06-14 | Perstorp Ab | En farmaceutisk komposition med foerbaettrad biotillgaenglighet avseende inositolfosfat |
| CA2146353C (en) * | 1992-10-05 | 2007-04-17 | Tomas Hudlicky | Syntheses of d-chiro-3-inosose and (+)-d-chiro-inositol |
| US5840294A (en) * | 1993-03-29 | 1998-11-24 | Queen's University At Kingston | Method for treating amyloidosis |
| US5972328A (en) * | 1993-03-29 | 1999-10-26 | Queen's University At Kingston | Method for treating amyloidosis |
| US5643562A (en) * | 1993-03-29 | 1997-07-01 | Queen's University Of Kingston | Method for treating amyloidosis |
| ES2202305T3 (es) * | 1993-04-05 | 2004-04-01 | Aveve N.V. | Hidrolisis de fitina y composicion de enzimas que tienen actividad hidrolizante de fitato. |
| CN1072637C (zh) * | 1993-08-11 | 2001-10-10 | 北兴化学工业株式会社 | D-手性肌醇的制造方法 |
| SE502574C2 (sv) * | 1994-01-25 | 1995-11-13 | Perstorp Ab | En farmaceutisk komposition med förbättrad biotillgänglighet hos inositolfosfat |
| US5858326A (en) * | 1995-06-06 | 1999-01-12 | Neurochem, Inc. | Methods of increasing amyloid deposition |
| US5756541A (en) * | 1996-03-11 | 1998-05-26 | Qlt Phototherapeutics Inc | Vision through photodynamic therapy of the eye |
| US6232486B1 (en) * | 1996-06-11 | 2001-05-15 | Nutrimed Biotech | Molecular probes and modulators for PI-PLC and PI 3-kinase |
| US5977078A (en) * | 1996-09-20 | 1999-11-02 | The Regents Of The Univesity Of California | Inositol polyphosphate derivatives and methods of using same |
| US5880099A (en) * | 1996-09-20 | 1999-03-09 | The Regents Of The University Of California | Inositol polyphosphates and methods of using same |
| US5998485A (en) * | 1997-06-16 | 1999-12-07 | Cedars-Sinai Medical Center | Method for modulating immune response with inositol |
| US6153603A (en) * | 1997-06-27 | 2000-11-28 | Perstorp Ab | Method of treating angiogenesis in tumor tissue |
| US6310073B1 (en) * | 1998-07-28 | 2001-10-30 | Queen's University At Kingston | Methods and compositions to treat glycosaminoglycan-associated molecular interactions |
| US6818430B1 (en) * | 1999-06-07 | 2004-11-16 | Hokko Chemical Industry Co., Ltd. | Process for producing L-epi-2-inosose and novel process for producing epi-inositol |
| US6329256B1 (en) * | 1999-09-24 | 2001-12-11 | Advanced Micro Devices, Inc. | Self-aligned damascene gate formation with low gate resistance |
| CZ20021346A3 (cs) * | 1999-10-18 | 2003-06-18 | Muscletech Research And Development Inc. | Potravinový doplněk pro růst svalové hmoty a síly |
| US6331313B1 (en) * | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| DE10031955A1 (de) * | 2000-06-30 | 2002-01-17 | Deutsches Krebsforsch | Curcumin-Derivate mit gegenüber Curcumin verbesserter Wasserlöslichkeit und diese enthaltende Arzneimittel |
| US7060695B2 (en) * | 2001-02-06 | 2006-06-13 | Qlt, Inc. | Method to prevent vision loss |
| US8034803B2 (en) * | 2001-02-06 | 2011-10-11 | Qlt Inc. | Photodynamic therapy of occult age-related macular degeneration |
| US20030181531A1 (en) * | 2003-02-11 | 2003-09-25 | David Sherris | Compositions and methods of administering tubulin binding agents for the treatment of ocular diseases |
| US6599891B2 (en) * | 2001-07-20 | 2003-07-29 | Qlt Inc. | Treatment of macular edema |
| US20040058313A1 (en) * | 2002-04-24 | 2004-03-25 | Abreu Marcio Marc | Compositions, targets, methods and devices for the therapy of ocular and periocular disorders |
| US7521481B2 (en) * | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
| PT2058390E (pt) * | 2003-10-14 | 2013-04-24 | Hokko Chem Ind Co | Processo para a produção de cilo-inositol |
| US20060189582A1 (en) * | 2004-11-17 | 2006-08-24 | Mclaurin Joanne | Compositions and methods for treatment of disorders of protein aggregation |
-
2007
- 2007-03-09 EP EP07710726A patent/EP1996175A4/en not_active Withdrawn
- 2007-03-09 EA EA200801967A patent/EA200801967A1/ru unknown
- 2007-03-09 BR BRPI0708725-0A patent/BRPI0708725A2/pt not_active IP Right Cessation
- 2007-03-09 KR KR1020087024122A patent/KR20090026247A/ko not_active Ceased
- 2007-03-09 CA CA002644804A patent/CA2644804A1/en not_active Abandoned
- 2007-03-09 US US12/282,030 patent/US20100113613A1/en not_active Abandoned
- 2007-03-09 JP JP2008557568A patent/JP2009529502A/ja active Pending
- 2007-03-09 AU AU2007222864A patent/AU2007222864A1/en not_active Abandoned
- 2007-03-09 NZ NZ571181A patent/NZ571181A/en not_active IP Right Cessation
- 2007-03-09 WO PCT/CA2007/000395 patent/WO2007101353A1/en not_active Ceased
- 2007-03-09 MX MX2008011553A patent/MX2008011553A/es not_active Application Discontinuation
- 2007-03-09 CN CN201210257027XA patent/CN103054837A/zh active Pending
-
2008
- 2008-09-08 IL IL193970A patent/IL193970A0/en unknown
-
2009
- 2009-11-24 ZA ZA2009/08303A patent/ZA200908303B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0708725A2 (pt) | 2011-06-07 |
| CN103054837A (zh) | 2013-04-24 |
| CA2644804A1 (en) | 2007-09-13 |
| WO2007101353A1 (en) | 2007-09-13 |
| IL193970A0 (en) | 2009-08-03 |
| JP2009529502A (ja) | 2009-08-20 |
| EA200801967A1 (ru) | 2009-04-28 |
| US20100113613A1 (en) | 2010-05-06 |
| MX2008011553A (es) | 2008-12-09 |
| EP1996175A1 (en) | 2008-12-03 |
| NZ571181A (en) | 2011-12-22 |
| KR20090026247A (ko) | 2009-03-12 |
| AU2007222864A1 (en) | 2007-09-13 |
| AU2007222864A8 (en) | 2010-06-10 |
| EP1996175A4 (en) | 2009-06-10 |
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