PL2341047T3 - Pochodna cykloheksanowa i jej farmaceutyczne zastosowanie - Google Patents
Pochodna cykloheksanowa i jej farmaceutyczne zastosowanieInfo
- Publication number
- PL2341047T3 PL2341047T3 PL09823687T PL09823687T PL2341047T3 PL 2341047 T3 PL2341047 T3 PL 2341047T3 PL 09823687 T PL09823687 T PL 09823687T PL 09823687 T PL09823687 T PL 09823687T PL 2341047 T3 PL2341047 T3 PL 2341047T3
- Authority
- PL
- Poland
- Prior art keywords
- pharmaceutical use
- cyclohexane derivative
- cyclohexane
- derivative
- pharmaceutical
- Prior art date
Links
- 125000000113 cyclohexyl group Chemical class [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008281258 | 2008-10-31 | ||
| JP2009176619 | 2009-07-29 | ||
| PCT/JP2009/068644 WO2010050577A1 (ja) | 2008-10-31 | 2009-10-30 | シクロヘキサン誘導体及びその医薬用途 |
| EP09823687.0A EP2341047B1 (en) | 2008-10-31 | 2009-10-30 | Cyclohexane derivative and pharmaceutical use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2341047T3 true PL2341047T3 (pl) | 2015-03-31 |
Family
ID=42128936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09823687T PL2341047T3 (pl) | 2008-10-31 | 2009-10-30 | Pochodna cykloheksanowa i jej farmaceutyczne zastosowanie |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8247569B2 (pl) |
| EP (1) | EP2341047B1 (pl) |
| JP (1) | JP5522031B2 (pl) |
| KR (1) | KR101313658B1 (pl) |
| CN (1) | CN102203068B (pl) |
| AU (1) | AU2009310807B2 (pl) |
| BR (1) | BRPI0919526B8 (pl) |
| CA (1) | CA2739883C (pl) |
| DK (1) | DK2341047T3 (pl) |
| ES (1) | ES2525708T3 (pl) |
| MX (1) | MX2011004576A (pl) |
| PL (1) | PL2341047T3 (pl) |
| PT (1) | PT2341047E (pl) |
| RU (1) | RU2478621C2 (pl) |
| TW (1) | TWI435874B (pl) |
| WO (1) | WO2010050577A1 (pl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2554541T3 (pl) * | 2010-03-31 | 2016-06-30 | Toray Industries | Środek terapeutyczny lub środek profilaktyczny na fibromialgię |
| PL2562160T3 (pl) * | 2010-03-31 | 2015-03-31 | Toray Industries | Środek leczniczy lub środek profilaktyczny do stosowania w zaburzeniach gromadzenia moczu |
| BR112012024346A2 (pt) | 2010-04-28 | 2016-05-24 | Toray Industries | agente terapêutico ou agente profilático para a doença de alzheimer |
| WO2012015027A1 (ja) * | 2010-07-30 | 2012-02-02 | 東レ株式会社 | 神経障害性疼痛の治療剤又は予防剤 |
| CA3161836A1 (en) * | 2013-12-11 | 2015-06-18 | Celgene Quanticel Research, Inc. | Inhibitors of lysine specific demethylase-1 |
| WO2015115509A1 (ja) | 2014-01-29 | 2015-08-06 | 東レ株式会社 | 多発性硬化症の治療剤又は予防剤 |
| PE20161438A1 (es) * | 2014-05-01 | 2017-01-18 | Celgene Quanticel Res Inc | Inhibidores de desmetilasa 1 especifica a lisina |
| WO2018181859A1 (ja) * | 2017-03-31 | 2018-10-04 | 東レ株式会社 | 抗がん剤誘発末梢神経障害の治療剤又は予防剤 |
| BR112021012449A2 (pt) | 2018-12-26 | 2021-09-08 | Toray Industries, Inc. | Agente para promoção da função de advilina, derivado de amina cíclica, e, medicamento |
| CN115521190A (zh) * | 2022-09-20 | 2022-12-27 | 阜阳欣奕华制药科技有限公司 | 乙炔基环己醇的制备方法及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6058981A (ja) * | 1983-09-09 | 1985-04-05 | Takeda Chem Ind Ltd | ５−ピリジル−１，３−チアゾ−ル誘導体，その製造法およびそれを含んでなる医薬組成物 |
| EP0149884B1 (en) * | 1983-09-09 | 1992-12-16 | Takeda Chemical Industries, Ltd. | 5-pyridyl-1,3-thiazole derivatives, their production and use |
| KR100345943B1 (ko) * | 1993-12-20 | 2002-11-30 | 후지사와 야꾸힝 고교 가부시키가이샤 | 4,5-디아릴옥사졸유도체 |
| GB9713726D0 (en) * | 1997-06-30 | 1997-09-03 | Ciba Geigy Ag | Organic compounds |
| ATE257703T1 (de) * | 1997-10-27 | 2004-01-15 | Takeda Chemical Industries Ltd | 1,3-thiazole als adenosine a3 rezeptor antagonisten zur behandlung von asthma, allergien und diabetes |
| AU4308300A (en) | 1999-05-03 | 2000-11-17 | Dr. Reddy's Research Foundation | Pyrazoles having antiinflammatory activity |
| BR0316332A (pt) | 2002-12-02 | 2005-09-27 | Astellas Pharma Inc | Composto pirazólico, composição farmacêutica e agente analgésico contendo o mesmo, processo para sua preparação e seu uso e pacote comercial |
| RU2005120779A (ru) * | 2002-12-02 | 2006-01-20 | Фудзисава Фармасьютикал Ко., Лтд. (JP) | Производные пиразола |
| AU2002953019A0 (en) * | 2002-12-02 | 2002-12-12 | Fujisawa Pharmaceutical Co., Ltd. | Azole derivatives |
| JP2007197324A (ja) * | 2006-01-23 | 2007-08-09 | Toray Ind Inc | ２，４，５−置換−１，３−アゾール誘導体 |
| CA2647603A1 (en) | 2006-03-27 | 2007-10-04 | Toray Industries, Inc. | Ureide derivative and use thereof for medical purposes |
| WO2008105383A1 (ja) | 2007-02-26 | 2008-09-04 | Toray Industries, Inc. | ピラゾール誘導体およびその医薬用途 |
-
2009
- 2009-10-29 TW TW098136604A patent/TWI435874B/zh not_active IP Right Cessation
- 2009-10-30 CA CA2739883A patent/CA2739883C/en active Active
- 2009-10-30 JP JP2010502106A patent/JP5522031B2/ja not_active Expired - Fee Related
- 2009-10-30 PT PT98236870T patent/PT2341047E/pt unknown
- 2009-10-30 WO PCT/JP2009/068644 patent/WO2010050577A1/ja not_active Ceased
- 2009-10-30 CN CN200980143945.6A patent/CN102203068B/zh active Active
- 2009-10-30 ES ES09823687.0T patent/ES2525708T3/es active Active
- 2009-10-30 AU AU2009310807A patent/AU2009310807B2/en not_active Ceased
- 2009-10-30 RU RU2011121809/04A patent/RU2478621C2/ru not_active IP Right Cessation
- 2009-10-30 EP EP09823687.0A patent/EP2341047B1/en active Active
- 2009-10-30 PL PL09823687T patent/PL2341047T3/pl unknown
- 2009-10-30 KR KR1020117009913A patent/KR101313658B1/ko not_active Expired - Fee Related
- 2009-10-30 DK DK09823687.0T patent/DK2341047T3/en active
- 2009-10-30 BR BRPI0919526A patent/BRPI0919526B8/pt active IP Right Grant
- 2009-10-30 MX MX2011004576A patent/MX2011004576A/es active IP Right Grant
- 2009-10-30 US US13/126,901 patent/US8247569B2/en active Active
-
2012
- 2012-06-27 US US13/534,093 patent/US8349874B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20110201650A1 (en) | 2011-08-18 |
| EP2341047A4 (en) | 2012-08-29 |
| AU2009310807A1 (en) | 2010-05-06 |
| KR101313658B1 (ko) | 2013-10-02 |
| BRPI0919526B1 (pt) | 2020-03-17 |
| TWI435874B (zh) | 2014-05-01 |
| US8247569B2 (en) | 2012-08-21 |
| TW201022226A (en) | 2010-06-16 |
| BRPI0919526B8 (pt) | 2021-05-25 |
| CA2739883A1 (en) | 2010-05-06 |
| WO2010050577A1 (ja) | 2010-05-06 |
| CN102203068B (zh) | 2014-03-19 |
| KR20110067053A (ko) | 2011-06-20 |
| RU2011121809A (ru) | 2012-12-10 |
| EP2341047A1 (en) | 2011-07-06 |
| EP2341047B1 (en) | 2014-10-15 |
| BRPI0919526A2 (pt) | 2015-12-08 |
| MX2011004576A (es) | 2011-06-17 |
| US8349874B2 (en) | 2013-01-08 |
| AU2009310807B2 (en) | 2012-02-23 |
| JPWO2010050577A1 (ja) | 2012-03-29 |
| PT2341047E (pt) | 2015-01-14 |
| ES2525708T3 (es) | 2014-12-29 |
| US20120270906A1 (en) | 2012-10-25 |
| DK2341047T3 (en) | 2015-01-19 |
| CA2739883C (en) | 2013-05-28 |
| JP5522031B2 (ja) | 2014-06-18 |
| RU2478621C2 (ru) | 2013-04-10 |
| CN102203068A (zh) | 2011-09-28 |
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