EA200800925A1 - Медицинский искусственный трансплантат ствола нерва, содержащий фиброин шёлка, и способ его изготовления - Google Patents

Медицинский искусственный трансплантат ствола нерва, содержащий фиброин шёлка, и способ его изготовления

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Publication number
EA200800925A1
EA200800925A1 EA200800925A EA200800925A EA200800925A1 EA 200800925 A1 EA200800925 A1 EA 200800925A1 EA 200800925 A EA200800925 A EA 200800925A EA 200800925 A EA200800925 A EA 200800925A EA 200800925 A1 EA200800925 A1 EA 200800925A1
Authority
EA
Eurasian Patent Office
Prior art keywords
silk fibroin
vessel
fibroin
manufacturing
transplante
Prior art date
Application number
EA200800925A
Other languages
English (en)
Other versions
EA016085B1 (ru
Inventor
Ксяосонг Гу
Юмин Янг
Фэй Динг
Пейюн Жанг
Ян Лью
Мэй Лью
Ксюмей Чен
Ксяодонг Ванг
Original Assignee
Нантонг Юниверсити
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36138326&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200800925(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Нантонг Юниверсити filed Critical Нантонг Юниверсити
Publication of EA200800925A1 publication Critical patent/EA200800925A1/ru
Publication of EA016085B1 publication Critical patent/EA016085B1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/047—Other specific proteins or polypeptides not covered by A61L31/044 - A61L31/046
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L31/129—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Composite Materials (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Insects & Arthropods (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Animal Husbandry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

Предложен искусственный трансплантат ствола нерва, содержащий фиброин шелка и используемый для соединения поврежденных нервов, а также способ его изготовления. Медицинский искусственный трансплантат ствола нерва содержит сосуд или сосуд и волокнистый каркас, причём по меньшей мере одна из указанных составляющих содержит фиброин шелка, а стенка сосуда имеет трехмерную структуру с множеством микропор. Способ изготовления содержит следующие этапы: изготовление из шелка волокна фиброина шелка; изготовление из волокна фиброина шелка сосуда или волокнистого каркаса, содержащего фиброин шёлка, и соединение волокнистого каркаса с сосудом, а именно вставка волокнистого каркаса в сосуд.
EA200800925A 2005-09-28 2005-12-31 Медицинский искусственный трансплантат ствола нерва, содержащий фиброин шелка, и способ его изготовления EA016085B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB2005100946832A CN100382772C (zh) 2005-09-28 2005-09-28 含蚕丝丝素的医用神经移植物的制备方法
PCT/CN2005/002423 WO2007036084A1 (fr) 2005-09-28 2005-12-31 Greffon nerveux artificiel à usage médical contenant de la fibroïne de soie et procédé d’élaboration

Publications (2)

Publication Number Publication Date
EA200800925A1 true EA200800925A1 (ru) 2008-10-30
EA016085B1 EA016085B1 (ru) 2012-02-28

Family

ID=36138326

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200800925A EA016085B1 (ru) 2005-09-28 2005-12-31 Медицинский искусственный трансплантат ствола нерва, содержащий фиброин шелка, и способ его изготовления

Country Status (11)

Country Link
US (1) US20080249639A1 (ru)
EP (1) EP1938774B2 (ru)
JP (1) JP2009509594A (ru)
KR (1) KR20080049095A (ru)
CN (1) CN100382772C (ru)
AT (1) ATE506027T1 (ru)
AU (1) AU2005336876B2 (ru)
BR (1) BRPI0520636A2 (ru)
DE (1) DE602005027620D1 (ru)
EA (1) EA016085B1 (ru)
WO (1) WO2007036084A1 (ru)

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KR101150826B1 (ko) * 2010-05-19 2012-06-11 한림대학교 산학협력단 실크 피브로인으로부터 제조되는 인공 뇌경막 및 그 제조방법
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US9925301B2 (en) * 2012-04-06 2018-03-27 Trustees Of Tufts College Methods of producing and using silk microfibers
EP2712955A1 (en) 2012-09-27 2014-04-02 Ludwig Boltzmann Gesellschaft GmbH Product made of silk
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CN110585480B (zh) 2019-10-08 2021-10-29 东南大学 一种自支撑丝素蛋白导管支架的成型方法
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Also Published As

Publication number Publication date
BRPI0520636A2 (pt) 2009-05-19
AU2005336876B2 (en) 2012-09-06
ATE506027T1 (de) 2011-05-15
US20080249639A1 (en) 2008-10-09
EP1938774A1 (en) 2008-07-02
WO2007036084A1 (fr) 2007-04-05
EP1938774B1 (en) 2011-04-20
CN100382772C (zh) 2008-04-23
EA016085B1 (ru) 2012-02-28
KR20080049095A (ko) 2008-06-03
JP2009509594A (ja) 2009-03-12
AU2005336876A1 (en) 2007-04-05
DE602005027620D1 (de) 2011-06-01
EP1938774B2 (en) 2014-05-21
EP1938774A4 (en) 2010-01-20
CN1742690A (zh) 2006-03-08

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