EA200600522A1 - Комбинации пиримидинсодержащего nnrti с ингибиторами обратной транскриптазы - Google Patents

Комбинации пиримидинсодержащего nnrti с ингибиторами обратной транскриптазы

Info

Publication number
EA200600522A1
EA200600522A1 EA200600522A EA200600522A EA200600522A1 EA 200600522 A1 EA200600522 A1 EA 200600522A1 EA 200600522 A EA200600522 A EA 200600522A EA 200600522 A EA200600522 A EA 200600522A EA 200600522 A1 EA200600522 A1 EA 200600522A1
Authority
EA
Eurasian Patent Office
Prior art keywords
reverse transcriptase
pyrimidins
combination
transcriptase inhibitors
nnrti
Prior art date
Application number
EA200600522A
Other languages
English (en)
Other versions
EA014840B1 (ru
Inventor
Пол Стоффелс
Original Assignee
Тиботек Фармасьютикалз Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43778148&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200600522(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Тиботек Фармасьютикалз Лтд. filed Critical Тиботек Фармасьютикалз Лтд.
Priority claimed from PCT/EP2004/052028 external-priority patent/WO2005021001A1/en
Publication of EA200600522A1 publication Critical patent/EA200600522A1/ru
Publication of EA014840B1 publication Critical patent/EA014840B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Настоящее изобретение относится к комбинациям пиримидинсодержащего ингибитора NNRTI, именуемого ТМС278, с ингибиторами нуклеозид-обратной транскриптазы, такими как эмтрицитабин, ламивудин или абакавир, и/или ингибиторами нуклеотид-обратной транскриптазы, такими как тенофовир, которые пригодны для лечения ВИЧ-инфицированных субъектов и для профилактики передачи или инфицирования ВИЧ.
EA200600522A 2003-09-03 2004-09-03 Комбинации пиримидинсодержащего nnrti с ингибиторами обратной транскриптазы EA014840B1 (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US49977103P 2003-09-03 2003-09-03
EP03103275 2003-09-03
EP03103319 2003-09-08
EP03103335 2003-09-10
EP03103668 2003-10-02
US50848603P 2003-10-03 2003-10-03
PCT/EP2004/052028 WO2005021001A1 (en) 2003-09-03 2004-09-03 Combinations of a pyrimidine containing nnrti with rt inhibitors

Publications (2)

Publication Number Publication Date
EA200600522A1 true EA200600522A1 (ru) 2006-08-25
EA014840B1 EA014840B1 (ru) 2011-02-28

Family

ID=43778148

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200600522A EA014840B1 (ru) 2003-09-03 2004-09-03 Комбинации пиримидинсодержащего nnrti с ингибиторами обратной транскриптазы

Country Status (9)

Country Link
KR (2) KR101638999B1 (ru)
CN (1) CN102319433A (ru)
DK (1) DK1663240T4 (ru)
EA (1) EA014840B1 (ru)
ES (1) ES2542017T5 (ru)
HU (1) HUE025576T2 (ru)
PT (1) PT1663240E (ru)
SI (1) SI1663240T2 (ru)
TW (1) TWI365744B (ru)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3429B1 (ar) * 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز

Also Published As

Publication number Publication date
HUE025576T2 (en) 2016-04-28
CN102319433A (zh) 2012-01-18
KR101638999B1 (ko) 2016-07-12
DK1663240T4 (da) 2023-04-17
KR20130127515A (ko) 2013-11-22
ES2542017T3 (es) 2015-07-29
SI1663240T2 (sl) 2023-05-31
DK1663240T3 (en) 2015-07-20
KR20110132475A (ko) 2011-12-07
SI1663240T1 (sl) 2015-10-30
PT1663240E (pt) 2015-09-01
KR101539245B1 (ko) 2015-07-27
EA014840B1 (ru) 2011-02-28
ES2542017T5 (es) 2023-06-15
TWI365744B (en) 2012-06-11
TW200524612A (en) 2005-08-01

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Legal Events

Date Code Title Description
ND4A Extension of term of a eurasian patent
TC4A Change in name of a patent proprietor in a eurasian patent
PC4A Registration of transfer of a eurasian patent by assignment
ND4A Extension of term of a eurasian patent