EA037738B1 - Кристаллические формы ингибиторов глутаминазы - Google Patents
Кристаллические формы ингибиторов глутаминазы Download PDFInfo
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- EA037738B1 EA037738B1 EA201790337A EA201790337A EA037738B1 EA 037738 B1 EA037738 B1 EA 037738B1 EA 201790337 A EA201790337 A EA 201790337A EA 201790337 A EA201790337 A EA 201790337A EA 037738 B1 EA037738 B1 EA 037738B1
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- cancer
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
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| US9682952B2 (en) | 2012-09-04 | 2017-06-20 | Celgene Corporation | Isotopologues of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl) piperidine-2-6-dione and methods of preparation thereof |
| HRP20211610T1 (hr) | 2012-11-16 | 2022-02-04 | Calithera Biosciences, Inc. | Inhibitori heterocikličke glutaminaze |
| JP6798890B2 (ja) | 2014-06-13 | 2020-12-09 | キャリセラ バイオサイエンシーズ， インコーポレイテッド | グルタミナーゼ阻害剤との併用療法 |
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| US10441587B2 (en) | 2015-04-06 | 2019-10-15 | Calithera Biosciences, Inc. | Treatment of lung cancer with inhibitors of glutaminase |
| US10258619B2 (en) | 2015-10-05 | 2019-04-16 | Calithera Biosciences, Inc. | Combination therapy with glutaminase inhibitors and immuno-oncology agents |
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| EP3503893A4 (en) | 2016-08-25 | 2020-04-29 | Calithera Biosciences, Inc. | COMBINATION THERAPY WITH GLUTAMINE INHIBITORS |
| US20210177880A1 (en) * | 2017-10-31 | 2021-06-17 | President And Fellows Of Harvard College | Methods and compositions for treating acute myeloid leukemia |
| AU2020249868A1 (en) * | 2019-03-26 | 2021-10-21 | Tonix Pharma Holdings Limited | Salt forms of S-(N, N-diethylcarbamoyl)glutathione |
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| BR112017002403A2 (pt) | 2017-12-05 |
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| AU2015300825B2 (en) | 2019-10-10 |
| KR20170082494A (ko) | 2017-07-14 |
| EP3193876A4 (en) | 2017-12-27 |
| CN106999490A (zh) | 2017-08-01 |
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