SG11201700816YA - Crystal forms of glutaminase inhibitors - Google Patents

Crystal forms of glutaminase inhibitors

Info

Publication number
SG11201700816YA
SG11201700816YA SG11201700816YA SG11201700816YA SG11201700816YA SG 11201700816Y A SG11201700816Y A SG 11201700816YA SG 11201700816Y A SG11201700816Y A SG 11201700816YA SG 11201700816Y A SG11201700816Y A SG 11201700816YA SG 11201700816Y A SG11201700816Y A SG 11201700816YA
Authority
SG
Singapore
Prior art keywords
crystal forms
glutaminase inhibitors
glutaminase
inhibitors
crystal
Prior art date
Application number
SG11201700816YA
Inventor
Timothy F Stanton
James J Springer
Jacqueline N Williams
Original Assignee
Calithera Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calithera Biosciences Inc filed Critical Calithera Biosciences Inc
Publication of SG11201700816YA publication Critical patent/SG11201700816YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11201700816YA 2014-08-07 2015-08-07 Crystal forms of glutaminase inhibitors SG11201700816YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462034547P 2014-08-07 2014-08-07
PCT/US2015/044301 WO2016022969A1 (en) 2014-08-07 2015-08-07 Crystal forms of glutaminase inhibitors

Publications (1)

Publication Number Publication Date
SG11201700816YA true SG11201700816YA (en) 2017-02-27

Family

ID=55264662

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201700816YA SG11201700816YA (en) 2014-08-07 2015-08-07 Crystal forms of glutaminase inhibitors

Country Status (13)

Country Link
US (2) US10316030B2 (en)
EP (1) EP3193876B1 (en)
JP (3) JP6889101B2 (en)
KR (1) KR20170082494A (en)
CN (1) CN106999490A (en)
AU (2) AU2015300825B2 (en)
BR (1) BR112017002403A2 (en)
CA (1) CA2957225A1 (en)
EA (1) EA037738B1 (en)
IL (1) IL250391B (en)
MX (1) MX2017001620A (en)
SG (1) SG11201700816YA (en)
WO (1) WO2016022969A1 (en)

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US8604016B2 (en) 2011-11-21 2013-12-10 Calithera Biosciences Inc. Heterocyclic inhibitors of glutaminase
JP2015531776A (en) 2012-09-04 2015-11-05 セルジーン コーポレイション Isotopologue of 3- (5-amino-2-methyl-4-oxoquinazolin-3 (4H) -yl) piperidine-2,6-dione and process for producing the same
SG11201503720SA (en) 2012-11-16 2015-06-29 Calithera Biosciences Inc Heterocyclic glutaminase inhibitors
JP6798890B2 (en) 2014-06-13 2020-12-09 キャリセラ バイオサイエンシーズ， インコーポレイテッド Combination therapy with glutaminase inhibitors
CA2957225A1 (en) 2014-08-07 2016-02-11 Calithera Biosciences, Inc. Crystal forms of glutaminase inhibitors
EP3277276B1 (en) * 2015-03-30 2020-11-04 Calithera Biosciences, Inc. Methods of administering glutaminase inhibitors
BR112017021312A2 (en) 2015-04-06 2018-06-26 Calithera Biosciences Inc Lung cancer treatment with glutaminase inhibitors
CA3000996A1 (en) 2015-10-05 2017-04-13 Calithera Biosciences, Inc. Combination therapy with glutaminase inhibitors and immuno-oncology agents
WO2018039544A1 (en) 2016-08-25 2018-03-01 Calithera Biosciences, Inc. Combination therapy with glutaminase inhibitors
EP3503893A4 (en) 2016-08-25 2020-04-29 Calithera Biosciences, Inc. Combination therapy with glutaminase inhibitors
US20210177880A1 (en) * 2017-10-31 2021-06-17 President And Fellows Of Harvard College Methods and compositions for treating acute myeloid leukemia
EP3946601A1 (en) * 2019-03-26 2022-02-09 Tonix Pharma Holdings Limited Salt forms of s-(n, n-diethylcarbamoyl)glutathione

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Also Published As

Publication number Publication date
JP2017523991A (en) 2017-08-24
EA201790337A1 (en) 2017-09-29
US10676472B2 (en) 2020-06-09
EP3193876A1 (en) 2017-07-26
US20170226101A1 (en) 2017-08-10
US20190359607A1 (en) 2019-11-28
AU2015300825A1 (en) 2017-03-09
KR20170082494A (en) 2017-07-14
MX2017001620A (en) 2017-05-10
WO2016022969A1 (en) 2016-02-11
CN106999490A (en) 2017-08-01
JP2020037588A (en) 2020-03-12
IL250391B (en) 2021-10-31
BR112017002403A2 (en) 2017-12-05
JP2021165286A (en) 2021-10-14
AU2015300825B2 (en) 2019-10-10
EP3193876A4 (en) 2017-12-27
EP3193876B1 (en) 2022-01-12
AU2019284149A1 (en) 2020-01-30
JP6889101B2 (en) 2021-06-18
EA037738B1 (en) 2021-05-17
IL250391A0 (en) 2017-03-30
US10316030B2 (en) 2019-06-11
CA2957225A1 (en) 2016-02-11

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