EA030211B1 - Соединения на основе микрорнк и способы модулирования активности mir-21 - Google Patents

Соединения на основе микрорнк и способы модулирования активности mir-21 Download PDF

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Publication number
EA030211B1
EA030211B1 EA201491953A EA201491953A EA030211B1 EA 030211 B1 EA030211 B1 EA 030211B1 EA 201491953 A EA201491953 A EA 201491953A EA 201491953 A EA201491953 A EA 201491953A EA 030211 B1 EA030211 B1 EA 030211B1
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Eurasian Patent Office
Prior art keywords
nucleoside
nucleosides
modified oligonucleotide
certain embodiments
modified
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EA201491953A
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English (en)
Russian (ru)
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EA201491953A1 (ru
Inventor
Балкришен Бхат
Эрик Маркуссон
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Регьюлэс Терапьютикс Инк.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48289681&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA030211(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Регьюлэс Терапьютикс Инк. filed Critical Регьюлэс Терапьютикс Инк.
Publication of EA201491953A1 publication Critical patent/EA201491953A1/ru
Publication of EA030211B1 publication Critical patent/EA030211B1/ru

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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EA201491953A 2012-04-25 2013-04-24 Соединения на основе микрорнк и способы модулирования активности mir-21 EA030211B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261741783P 2012-04-25 2012-04-25
US201261717927P 2012-10-24 2012-10-24
US201361779913P 2013-03-13 2013-03-13
PCT/US2013/037913 WO2013163258A1 (en) 2012-04-25 2013-04-24 Microrna compounds and methods for modulating mir-21 activity

Publications (2)

Publication Number Publication Date
EA201491953A1 EA201491953A1 (ru) 2015-06-30
EA030211B1 true EA030211B1 (ru) 2018-07-31

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EA201491953A EA030211B1 (ru) 2012-04-25 2013-04-24 Соединения на основе микрорнк и способы модулирования активности mir-21

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US (5) US8969317B2 (cg-RX-API-DMAC7.html)
EP (1) EP2841579B1 (cg-RX-API-DMAC7.html)
JP (1) JP6322189B2 (cg-RX-API-DMAC7.html)
KR (4) KR102369722B1 (cg-RX-API-DMAC7.html)
CN (1) CN104254607B (cg-RX-API-DMAC7.html)
AR (1) AR090825A1 (cg-RX-API-DMAC7.html)
AU (1) AU2013251696B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014026639A8 (cg-RX-API-DMAC7.html)
CA (1) CA2869639A1 (cg-RX-API-DMAC7.html)
CL (3) CL2014002844A1 (cg-RX-API-DMAC7.html)
CO (1) CO7111303A2 (cg-RX-API-DMAC7.html)
CR (1) CR20140524A (cg-RX-API-DMAC7.html)
DO (1) DOP2014000233A (cg-RX-API-DMAC7.html)
EA (1) EA030211B1 (cg-RX-API-DMAC7.html)
EC (1) ECSP14028612A (cg-RX-API-DMAC7.html)
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PH (2) PH12023550488A1 (cg-RX-API-DMAC7.html)
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HRP20170557T2 (hr) 2011-04-25 2020-02-21 Regulus Therapeutics Inc. Mikrorna spojevi i postupci za modulaciju aktivnosti mir-21
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WO2013151663A1 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of membrane proteins
JP2015518475A (ja) * 2012-04-10 2015-07-02 インサーム（インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラルシェルシェ メディカル）Ｉｎｓｅｒｍ（Ｉｎｓｔｉｔｕｔ Ｎａｔｉｏｎａｌ Ｄｅｌａ Ｓａｎｔｅ Ｅｔｄｅ Ｌａ Ｒｅｃｈｅｒｃｈｅ Ｍｅｄｉｃａｌｅ） 非アルコール性脂肪性肝炎の治療方法
PE20142404A1 (es) 2012-04-25 2015-02-02 Regulus Therapeutics Inc Compuestos de microarn y metodos de modulacion de la actividad de mir-21
UA116639C2 (uk) 2012-10-09 2018-04-25 Рег'Юлес Терап'Ютікс Інк. Способи лікування синдрому альпорта
EP3459549B1 (en) * 2012-10-12 2022-04-06 Ionis Pharmaceuticals, Inc. Selective antisense compounds and uses thereof
HRP20220607T1 (hr) 2012-11-26 2022-06-24 Modernatx, Inc. Terminalno modificirana rna
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