EA029327B1 - Антитела, которые нейтрализуют рецептор пролактина, и их терапевтическое применение - Google Patents
Антитела, которые нейтрализуют рецептор пролактина, и их терапевтическое применение Download PDFInfo
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- EA029327B1 EA029327B1 EA201200851A EA201200851A EA029327B1 EA 029327 B1 EA029327 B1 EA 029327B1 EA 201200851 A EA201200851 A EA 201200851A EA 201200851 A EA201200851 A EA 201200851A EA 029327 B1 EA029327 B1 EA 029327B1
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Applications Claiming Priority (2)
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| EP09075546A EP2332995A1 (en) | 2009-12-10 | 2009-12-10 | Neutralizing prolactin receptor antibodies and their therapeutic use |
| PCT/EP2010/067747 WO2011069799A1 (en) | 2009-12-10 | 2010-11-18 | Neutralizing prolactin receptor antibodies and their therapeutic use |
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| EA201200851A1 EA201200851A1 (ru) | 2013-01-30 |
| EA029327B1 true EA029327B1 (ru) | 2018-03-30 |
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| EA201200851A EA029327B1 (ru) | 2009-12-10 | 2010-11-18 | Антитела, которые нейтрализуют рецептор пролактина, и их терапевтическое применение |
| EA201200860A EA028678B1 (ru) | 2009-12-10 | 2010-11-18 | Нейтрализующие пролактиновый рецептор антитела и их терапевтическое применение |
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| EA201200860A EA028678B1 (ru) | 2009-12-10 | 2010-11-18 | Нейтрализующие пролактиновый рецептор антитела и их терапевтическое применение |
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| EP2332995A1 (en) * | 2009-12-10 | 2011-06-15 | Bayer Schering Pharma Aktiengesellschaft | Neutralizing prolactin receptor antibodies and their therapeutic use |
| SG183443A1 (en) | 2010-03-01 | 2012-09-27 | Bayer Healthcare Llc | Optimized monoclonal antibodies against tissue factor pathway inhibitor (tfpi) |
| EP2530089A1 (en) * | 2011-06-03 | 2012-12-05 | Bayer Pharma Aktiengesellschaft | Neutralising prolactin receptor antibody Mat3 and its therapeutical use |
| SG11201405468QA (en) | 2012-03-14 | 2014-10-30 | Regeneron Pharma | Multispecific antigen-binding molecules and uses thereof |
| US9592297B2 (en) * | 2012-08-31 | 2017-03-14 | Bayer Healthcare Llc | Antibody and protein formulations |
| US8883979B2 (en) * | 2012-08-31 | 2014-11-11 | Bayer Healthcare Llc | Anti-prolactin receptor antibody formulations |
| MX382301B (es) | 2012-12-24 | 2025-03-13 | Abbvie Inc | Proteinas de union al receptor de prolactina y usos de las mismas. |
| CA2906101A1 (en) * | 2013-03-15 | 2014-09-18 | Bayer Healthcare Llc | Anti-prolactin receptor antibody formulations |
| TWI641620B (zh) | 2013-08-21 | 2018-11-21 | 再生元醫藥公司 | 抗－ｐｒｌｒ抗體及其用途 |
| US9545451B2 (en) | 2013-08-21 | 2017-01-17 | Regeneron Pharmaceuticals, Inc. | Anti-PRLR antibodies and methods for killing PRLR-expressing cells |
| WO2015168474A1 (en) | 2014-04-30 | 2015-11-05 | President And Fellows Of Harvard College | Fusion proteins for treating cancer and related methods |
| KR20170063881A (ko) | 2014-10-02 | 2017-06-08 | 시티 오브 호프 | 다가 메디토프, 메디토프 결합 항체 및 이의 용도 |
| KR20170105558A (ko) * | 2015-01-30 | 2017-09-19 | 각코우호우징 사이타마이카다이가쿠 | 항 alk2 항체 |
| KR20180025865A (ko) | 2015-07-06 | 2018-03-09 | 리제너론 파마슈티칼스 인코포레이티드 | 다중특이적 항원 결합 분자 및 이의 용도 |
| US11352446B2 (en) | 2016-04-28 | 2022-06-07 | Regeneron Pharmaceuticals, Inc. | Methods of making multispecific antigen-binding molecules |
| WO2018102304A1 (en) | 2016-11-29 | 2018-06-07 | Regeneron Pharmaceuticals, Inc. | Methods of treating prlr positive breast cancer |
| FR3062213B1 (fr) * | 2017-01-20 | 2021-02-26 | Endodiag | Utilisation du recepteur cd71 dans la detection et le traitement de l’endometriose |
| TW201836647A (zh) | 2017-04-06 | 2018-10-16 | 美商艾伯維有限公司 | 抗－ｐｒｌｒ抗體藥物軛合物（ａｄｃ）及其用途 |
| CA3062880A1 (en) * | 2017-05-12 | 2018-11-15 | Millennium Pharmaceuticals, Inc. | Treatment of gastroparesis with triazaspiro[4.5]decanone |
| KR20200027494A (ko) | 2017-07-10 | 2020-03-12 | 바이엘 파마 악티엔게젤샤프트 | 남성 및 여성 패턴 탈모를 위한 프로락틴 수용체 항체 |
| KR20200118151A (ko) | 2018-02-07 | 2020-10-14 | 리제너론 파마슈티칼스 인코포레이티드 | 치료 단백질 전달을 위한 방법 및 조성물 |
| WO2019169330A1 (en) * | 2018-03-02 | 2019-09-06 | Oncolix, Inc. | Method for treating cancers expressing prolactin receptor |
| CN109627340B (zh) * | 2018-12-05 | 2021-02-12 | 上海交通大学 | Cd3和prlr双特异性抗体及其构建与应用 |
| US10467487B1 (en) * | 2018-12-11 | 2019-11-05 | Chongqing Jinkang New Energy Automobile Co., Ltd. | Fusion-based traffic light recognition for autonomous driving |
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