EA025345B1 - Гидроксиамидные соединения пиримидина в качестве ингибиторов деацетилаз белков и фармацевтические композиции для лечения заболевания, обусловленного hdac6, включающие эти соединения - Google Patents

Гидроксиамидные соединения пиримидина в качестве ингибиторов деацетилаз белков и фармацевтические композиции для лечения заболевания, обусловленного hdac6, включающие эти соединения Download PDF

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Publication number
EA025345B1
EA025345B1 EA201390711A EA201390711A EA025345B1 EA 025345 B1 EA025345 B1 EA 025345B1 EA 201390711 A EA201390711 A EA 201390711A EA 201390711 A EA201390711 A EA 201390711A EA 025345 B1 EA025345 B1 EA 025345B1
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Eurasian Patent Office
Prior art keywords
compound
compounds
pharmaceutically acceptable
disease
cancer
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EA201390711A
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English (en)
Russian (ru)
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EA201390711A1 (ru
Inventor
Джон Х. Ван Дюзер
Ральф Мацичек
Янбинг Динг
Нань Юй
Юн Цао
Юн Лю
Original Assignee
Эситайлон Фармасьютикалз, Инк.
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Application filed by Эситайлон Фармасьютикалз, Инк. filed Critical Эситайлон Фармасьютикалз, Инк.
Publication of EA201390711A1 publication Critical patent/EA201390711A1/ru
Publication of EA025345B1 publication Critical patent/EA025345B1/ru

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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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EA201390711A 2010-11-16 2011-11-15 Гидроксиамидные соединения пиримидина в качестве ингибиторов деацетилаз белков и фармацевтические композиции для лечения заболевания, обусловленного hdac6, включающие эти соединения EA025345B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41415810P 2010-11-16 2010-11-16
US201161503286P 2011-06-30 2011-06-30
PCT/US2011/060791 WO2012068109A2 (en) 2010-11-16 2011-11-15 Pyrimidine hydroxy amide compounds as protein deacetylase inhibitors and methods of use thereof

Publications (2)

Publication Number Publication Date
EA201390711A1 EA201390711A1 (ru) 2014-03-31
EA025345B1 true EA025345B1 (ru) 2016-12-30

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EA201390711A EA025345B1 (ru) 2010-11-16 2011-11-15 Гидроксиамидные соединения пиримидина в качестве ингибиторов деацетилаз белков и фармацевтические композиции для лечения заболевания, обусловленного hdac6, включающие эти соединения
EA201691121A EA201691121A1 (ru) 2010-11-16 2011-11-15 Гидроксиамидные соединения пиримидина в качестве ингибиторов деацетилаз белков и способы их применения

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US (3) US8614223B2 (OSRAM)
EP (2) EP2640709B1 (OSRAM)
JP (2) JP6041808B2 (OSRAM)
KR (1) KR20130115300A (OSRAM)
CN (2) CN103429574B (OSRAM)
AU (2) AU2011329028B2 (OSRAM)
BR (1) BR112013011868A2 (OSRAM)
CA (1) CA2818125A1 (OSRAM)
CL (1) CL2013001381A1 (OSRAM)
EA (2) EA025345B1 (OSRAM)
ES (1) ES2568260T3 (OSRAM)
IL (2) IL226326A0 (OSRAM)
MX (1) MX2013005392A (OSRAM)
NZ (2) NZ710405A (OSRAM)
PH (2) PH12013500964A1 (OSRAM)
PL (1) PL2640709T3 (OSRAM)
PT (1) PT2640709T (OSRAM)
SG (2) SG10201509324QA (OSRAM)
WO (1) WO2012068109A2 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2764718C2 (ru) * 2017-04-14 2022-01-19 Италфармако С.П.А. Селективные ингибиторы hdac6

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