EA024111B1 - Вакцина против вируса африканской чумы лошадей - Google Patents

Вакцина против вируса африканской чумы лошадей Download PDF

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Publication number
EA024111B1
EA024111B1 EA201100674A EA201100674A EA024111B1 EA 024111 B1 EA024111 B1 EA 024111B1 EA 201100674 A EA201100674 A EA 201100674A EA 201100674 A EA201100674 A EA 201100674A EA 024111 B1 EA024111 B1 EA 024111B1
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EA
Eurasian Patent Office
Prior art keywords
virus
sequence
promoter
recombinant
an8u
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Application number
EA201100674A
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English (en)
Russian (ru)
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EA201100674A1 (ru
Inventor
Жюль Мартен Минке
Жан-Кристоф Одонне
Алан Джон Гютри
Найджел Джеймс Маклохлан
Джианшенг Яо
Original Assignee
Мериал Лимитед
Те Риджентс Оф Те Юниверсити Оф Калифорния
Юниверсити Оф Претория
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41818403&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA024111(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Мериал Лимитед, Те Риджентс Оф Те Юниверсити Оф Калифорния, Юниверсити Оф Претория filed Critical Мериал Лимитед
Publication of EA201100674A1 publication Critical patent/EA201100674A1/ru
Publication of EA024111B1 publication Critical patent/EA024111B1/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/15Reoviridae, e.g. calf diarrhea virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24041Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12111Orbivirus, e.g. bluetongue virus
    • C12N2720/12122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12111Orbivirus, e.g. bluetongue virus
    • C12N2720/12134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA201100674A 2008-10-24 2009-10-22 Вакцина против вируса африканской чумы лошадей EA024111B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10807508P 2008-10-24 2008-10-24
US16351709P 2009-03-26 2009-03-26
PCT/US2009/061669 WO2010048394A2 (en) 2008-10-24 2009-10-22 Vaccine against african horse sickness virus

Publications (2)

Publication Number Publication Date
EA201100674A1 EA201100674A1 (ru) 2011-12-30
EA024111B1 true EA024111B1 (ru) 2016-08-31

Family

ID=41818403

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201100674A EA024111B1 (ru) 2008-10-24 2009-10-22 Вакцина против вируса африканской чумы лошадей

Country Status (19)

Country Link
US (3) US8168200B2 (OSRAM)
EP (1) EP2358742B1 (OSRAM)
JP (1) JP2012506699A (OSRAM)
KR (1) KR101719005B1 (OSRAM)
CN (1) CN102245627A (OSRAM)
AP (1) AP3334A (OSRAM)
AR (1) AR074055A1 (OSRAM)
AU (1) AU2009308331C1 (OSRAM)
BR (2) BRPI0920622B1 (OSRAM)
CA (1) CA2741333C (OSRAM)
CL (1) CL2011000922A1 (OSRAM)
EA (1) EA024111B1 (OSRAM)
ES (1) ES2681693T3 (OSRAM)
MX (1) MX2011004219A (OSRAM)
NZ (2) NZ592388A (OSRAM)
PL (1) PL2358742T3 (OSRAM)
PT (1) PT2358742T (OSRAM)
WO (1) WO2010048394A2 (OSRAM)
ZA (1) ZA201103031B (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0920622B1 (pt) * 2008-10-24 2019-11-12 Merial, Inc. vacina contra o vírus da doença equina africana
JP6260972B2 (ja) 2012-02-14 2018-01-17 メリアル インコーポレイテッド 狂犬病タンパク質及びox40タンパク質の両方を発現する組換えポックスウイルスベクター並びに前記ベクターから製造されるワクチン
EP3149158B1 (en) * 2014-11-04 2017-10-11 Deltamune (PTY) Limited Live attenuated african horsesickness virus
US10334248B2 (en) * 2015-05-29 2019-06-25 Qualcomm Incorporated Coding data using an enhanced context-adaptive binary arithmetic coding (CABAC) design
CN111867637B (zh) * 2018-03-19 2024-05-03 勃林格殷格翰动物保健有限公司 新ehv插入位点ul43
CN116041447A (zh) * 2022-12-29 2023-05-02 北京亿森宝生物科技有限公司 一种检测非洲马瘟病毒的试剂盒及其应用
CN116656731B (zh) * 2023-05-25 2024-04-12 军事科学院军事医学研究院军事兽医研究所 一种表达非洲猪瘟病毒多种蛋白的重组金丝雀痘病毒及其构建方法
WO2025013146A1 (ja) 2023-07-07 2025-01-16 中京油脂株式会社 分散体
CN117737310B (zh) * 2024-01-26 2024-07-16 中国农业科学院北京畜牧兽医研究所 非洲马瘟和西尼罗病毒的双重实时荧光mira检测引物探针组、试剂盒及方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA976424B (en) * 1996-07-05 1999-01-22 Agricultural Research Council Nucleic acid sequences coding for african horsesickness virus outer capsid components
US7163926B1 (en) * 1998-04-03 2007-01-16 Merial Adjuvant-containing vaccines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5505941A (en) * 1981-12-24 1996-04-09 Health Research, Inc. Recombinant avipox virus and method to induce an immune response
WO1992015672A1 (en) * 1991-03-07 1992-09-17 Virogenetics Corporation Genetically engineered vaccine strain
US5843456A (en) 1991-03-07 1998-12-01 Virogenetics Corporation Alvac poxvirus-rabies compositions and combination compositions and uses
FR2775601B1 (fr) * 1998-03-03 2001-09-21 Merial Sas Vaccins vivants recombines et adjuves
US7740863B2 (en) * 2001-04-06 2010-06-22 Merial Recombinant vaccine against West Nile Virus
US7862821B2 (en) * 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
BRPI0920622B1 (pt) * 2008-10-24 2019-11-12 Merial, Inc. vacina contra o vírus da doença equina africana

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA976424B (en) * 1996-07-05 1999-01-22 Agricultural Research Council Nucleic acid sequences coding for african horsesickness virus outer capsid components
US7163926B1 (en) * 1998-04-03 2007-01-16 Merial Adjuvant-containing vaccines

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 1 October 1993 (1993-10-01), Iwata H. et al.: "African Horse Sickness Virus 4, capsid protein VP2" XP002574277 Database accession no. P32553 abstract *
DATABASE EMBL 15 October 1992 (1992-10-15), Iwata H. et al.: "African Horse Sickness Virus 4, capsid protein VP2" XP002574276 Database accession no. M94680 abstract *
MACLACHLAN ET AL.: "Experiences with new generation vaccines against equine viral arteritis, West Nile disease and African horse sickness" VACCINE, vol. 25, no. 30, 10 July 2007 (2007-07-10), pages 5577-5582, XP022148595 ISSN: 0264-410X page 5580, left-hand column, paragraph 2 - right-hand column, line 1 *

Also Published As

Publication number Publication date
US20140120133A1 (en) 2014-05-01
BRPI0920622B1 (pt) 2019-11-12
KR101719005B1 (ko) 2017-03-22
AP3334A (en) 2015-07-31
PT2358742T (pt) 2018-06-04
US20100119546A1 (en) 2010-05-13
BR122019001455B1 (pt) 2021-01-19
AU2009308331B2 (en) 2014-08-21
AP2011005954A0 (en) 2011-10-31
BRPI0920622A2 (pt) 2016-10-04
CA2741333C (en) 2018-02-13
BRPI0920622A8 (pt) 2019-02-05
ZA201103031B (en) 2014-03-26
MX2011004219A (es) 2011-09-22
EA201100674A1 (ru) 2011-12-30
CL2011000922A1 (es) 2011-09-16
NZ592388A (en) 2012-03-30
ES2681693T3 (es) 2018-09-14
WO2010048394A3 (en) 2010-08-19
JP2012506699A (ja) 2012-03-22
AU2009308331C1 (en) 2015-07-09
AU2009308331A1 (en) 2010-04-29
PL2358742T3 (pl) 2018-08-31
AR074055A1 (es) 2010-12-22
US8168200B2 (en) 2012-05-01
EP2358742B1 (en) 2018-02-28
CN102245627A (zh) 2011-11-16
NZ598605A (en) 2014-04-30
KR20110092281A (ko) 2011-08-17
EP2358742A2 (en) 2011-08-24
WO2010048394A2 (en) 2010-04-29
US20120114691A1 (en) 2012-05-10
CA2741333A1 (en) 2010-04-29

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