CL2011000922A1 - Composicion de vacuna que comprende un vector de expresion canarypox capaz de expresar en un equino proteinas virales del virus de la peste equina africana (ahsv) vp2 y vp5; y su uso para inducir una respuesta inmune protectora contra la peste equina africana en un animal equino. - Google Patents

Composicion de vacuna que comprende un vector de expresion canarypox capaz de expresar en un equino proteinas virales del virus de la peste equina africana (ahsv) vp2 y vp5; y su uso para inducir una respuesta inmune protectora contra la peste equina africana en un animal equino.

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Publication number
CL2011000922A1
CL2011000922A1 CL2011000922A CL2011000922A CL2011000922A1 CL 2011000922 A1 CL2011000922 A1 CL 2011000922A1 CL 2011000922 A CL2011000922 A CL 2011000922A CL 2011000922 A CL2011000922 A CL 2011000922A CL 2011000922 A1 CL2011000922 A1 CL 2011000922A1
Authority
CL
Chile
Prior art keywords
equine
african horse
horse sickness
ahsv
response against
Prior art date
Application number
CL2011000922A
Other languages
English (en)
Inventor
Alan John Guthrie
Nigel James Maclachlan
Jiansheng Yao
Jules Maarten Minke
Jean-Christophe Audonnet
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41818403&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2011000922(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merial Inc filed Critical Merial Inc
Publication of CL2011000922A1 publication Critical patent/CL2011000922A1/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12111—Orbivirus, e.g. bluetongue virus
    • C12N2720/12122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12111—Orbivirus, e.g. bluetongue virus
    • C12N2720/12134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA PRESENTE INVENCIÓN DESCRIBE UNA COMPOSICIÓN DE VACUNA INMUNOGÉNICA CAPAZ DE PROVOCAR UNA<br /> RESPUESTA INMUNE PROTECTORA CONTRA LA PESTE EQUINA AFRICANA (AHSV) EN UN ANIMAL EQUINO, DONDE DICHA<br /> CORNPOSÍCÍÓ-I COMPRENDE: A) UN VECTOR DE CANARYPOX QUE COMPRENDE UNA MOLÉCULA DE ÁCIDO NUCLEÍCO QUE<br /> COMPRENDE DOS SECUENCIAS DE POLINUCLEÓTIDOS, DONDE DICHA MOLÉCULA DE ÁCIDO NUCLEÍCO CODIFICA Y ES CAPAZ<br /> DE EXPRESA. IN VIVO EN EL EQUINO, LOS POLIPÉPTIDOS VP2 Y VPS DEL VIRUS DE LA PESTE EQUINA AFRICANA; Y B) UN<br /> VEHÍCULO, DILUYENTE O EXCIPIENTE VETERINARIAMENTE ACEPTABLE. ADICIONALMENTE, DESCRIBE EL USO DE DICHA<br /> COMPOSICIÓN DE VACUNA INMUNOGÉNICA PARA LA PREPARACIÓN DE UN MEDICAMENTO ÚTIL PARA PROVOCAR UNA<br /> RESPUESTA INMUNE PROTECTORA CONTRA LA PESTE EQUINA AFRICANA EN UN ANIMAL EQUINO.
CL2011000922A 2008-10-24 2011-04-21 Composicion de vacuna que comprende un vector de expresion canarypox capaz de expresar en un equino proteinas virales del virus de la peste equina africana (ahsv) vp2 y vp5; y su uso para inducir una respuesta inmune protectora contra la peste equina africana en un animal equino. CL2011000922A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10807508P 2008-10-24 2008-10-24
US16351709P 2009-03-26 2009-03-26

Publications (1)

Publication Number Publication Date
CL2011000922A1 true CL2011000922A1 (es) 2011-09-16

Family

ID=41818403

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2011000922A CL2011000922A1 (es) 2008-10-24 2011-04-21 Composicion de vacuna que comprende un vector de expresion canarypox capaz de expresar en un equino proteinas virales del virus de la peste equina africana (ahsv) vp2 y vp5; y su uso para inducir una respuesta inmune protectora contra la peste equina africana en un animal equino.

Country Status (19)

Country Link
US (3) US8168200B2 (es)
EP (1) EP2358742B1 (es)
JP (1) JP2012506699A (es)
KR (1) KR101719005B1 (es)
CN (1) CN102245627A (es)
AP (1) AP3334A (es)
AR (1) AR074055A1 (es)
AU (1) AU2009308331C1 (es)
BR (2) BRPI0920622B1 (es)
CA (1) CA2741333C (es)
CL (1) CL2011000922A1 (es)
EA (1) EA024111B1 (es)
ES (1) ES2681693T3 (es)
MX (1) MX2011004219A (es)
NZ (2) NZ598605A (es)
PL (1) PL2358742T3 (es)
PT (1) PT2358742T (es)
WO (1) WO2010048394A2 (es)
ZA (1) ZA201103031B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0920622B1 (pt) * 2008-10-24 2019-11-12 Merial, Inc. vacina contra o vírus da doença equina africana
CN104203271B (zh) 2012-02-14 2017-08-25 梅里亚股份有限公司 表达狂犬病病毒和ox40蛋白的重组痘病毒载体及从其制造的疫苗
WO2016071850A1 (en) * 2014-11-04 2016-05-12 Deltamune (Pty) Limited Live attenuated african horsesickness virus
US10574993B2 (en) 2015-05-29 2020-02-25 Qualcomm Incorporated Coding data using an enhanced context-adaptive binary arithmetic coding (CABAC) design
EA202092165A1 (ru) * 2018-03-19 2021-02-25 Бёрингер Ингельхайм Ветмедика Гмбх Новый ehv сайт инсерции ul43
CN116041447A (zh) * 2022-12-29 2023-05-02 北京亿森宝生物科技有限公司 一种检测非洲马瘟病毒的试剂盒及其应用
CN116656731B (zh) * 2023-05-25 2024-04-12 军事科学院军事医学研究院军事兽医研究所 一种表达非洲猪瘟病毒多种蛋白的重组金丝雀痘病毒及其构建方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5505941A (en) * 1981-12-24 1996-04-09 Health Research, Inc. Recombinant avipox virus and method to induce an immune response
US5843456A (en) 1991-03-07 1998-12-01 Virogenetics Corporation Alvac poxvirus-rabies compositions and combination compositions and uses
JP3602530B2 (ja) * 1991-03-07 2004-12-15 ヴァイロジェネティクス コーポレイション 遺伝子操作したワクチン菌株
ZA976424B (en) * 1996-07-05 1999-01-22 Agricultural Research Council Nucleic acid sequences coding for african horsesickness virus outer capsid components
FR2775601B1 (fr) * 1998-03-03 2001-09-21 Merial Sas Vaccins vivants recombines et adjuves
FR2776928B1 (fr) * 1998-04-03 2000-06-23 Merial Sas Vaccins adn adjuves
US7740863B2 (en) * 2001-04-06 2010-06-22 Merial Recombinant vaccine against West Nile Virus
US7862821B2 (en) * 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
BRPI0920622B1 (pt) * 2008-10-24 2019-11-12 Merial, Inc. vacina contra o vírus da doença equina africana

Also Published As

Publication number Publication date
AU2009308331B2 (en) 2014-08-21
WO2010048394A3 (en) 2010-08-19
BRPI0920622A2 (pt) 2016-10-04
EA024111B1 (ru) 2016-08-31
CA2741333A1 (en) 2010-04-29
CN102245627A (zh) 2011-11-16
US20120114691A1 (en) 2012-05-10
NZ592388A (en) 2012-03-30
US20140120133A1 (en) 2014-05-01
CA2741333C (en) 2018-02-13
AP3334A (en) 2015-07-31
KR20110092281A (ko) 2011-08-17
MX2011004219A (es) 2011-09-22
AR074055A1 (es) 2010-12-22
EA201100674A1 (ru) 2011-12-30
US8168200B2 (en) 2012-05-01
KR101719005B1 (ko) 2017-03-22
BRPI0920622B1 (pt) 2019-11-12
ES2681693T3 (es) 2018-09-14
ZA201103031B (en) 2014-03-26
PL2358742T3 (pl) 2018-08-31
WO2010048394A2 (en) 2010-04-29
PT2358742T (pt) 2018-06-04
EP2358742B1 (en) 2018-02-28
AU2009308331A1 (en) 2010-04-29
BRPI0920622A8 (pt) 2019-02-05
AP2011005954A0 (en) 2011-10-31
BR122019001455B1 (pt) 2021-01-19
US20100119546A1 (en) 2010-05-13
EP2358742A2 (en) 2011-08-24
NZ598605A (en) 2014-04-30
AU2009308331C1 (en) 2015-07-09
JP2012506699A (ja) 2012-03-22

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