EA018536B1 - Фармацевтический препарат, содержащий толперизон - Google Patents

Фармацевтический препарат, содержащий толперизон Download PDF

Info

Publication number
EA018536B1
EA018536B1 EA201070747A EA201070747A EA018536B1 EA 018536 B1 EA018536 B1 EA 018536B1 EA 201070747 A EA201070747 A EA 201070747A EA 201070747 A EA201070747 A EA 201070747A EA 018536 B1 EA018536 B1 EA 018536B1
Authority
EA
Eurasian Patent Office
Prior art keywords
tolperisone
preparation according
pharmaceutical preparation
acid
pharmaceutical
Prior art date
Application number
EA201070747A
Other languages
English (en)
Russian (ru)
Other versions
EA201070747A1 (ru
Inventor
Оттилиа Балаж
Карой Тиханьи
Каталин Хорнок
Иштванне Киш-Варга
Мария Вираг-Хадаш
Original Assignee
Рихтер Гедеон Нирт.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Рихтер Гедеон Нирт. filed Critical Рихтер Гедеон Нирт.
Publication of EA201070747A1 publication Critical patent/EA201070747A1/ru
Publication of EA018536B1 publication Critical patent/EA018536B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA201070747A 2007-12-20 2008-12-18 Фармацевтический препарат, содержащий толперизон EA018536B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0700828A HUP0700828A2 (en) 2007-12-20 2007-12-20 Transdermal pharmaceutical compositions containing tolperisone alone and in combination
PCT/HU2008/000153 WO2009081217A1 (en) 2007-12-20 2008-12-18 Pharmaceutical formulations containing tolperisone

Publications (2)

Publication Number Publication Date
EA201070747A1 EA201070747A1 (ru) 2010-12-30
EA018536B1 true EA018536B1 (ru) 2013-08-30

Family

ID=89987953

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070747A EA018536B1 (ru) 2007-12-20 2008-12-18 Фармацевтический препарат, содержащий толперизон

Country Status (7)

Country Link
US (1) US20100273746A1 (https=)
EP (1) EP2231116A1 (https=)
JP (1) JP2011507826A (https=)
CA (1) CA2709538A1 (https=)
EA (1) EA018536B1 (https=)
HU (1) HUP0700828A2 (https=)
WO (1) WO2009081217A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2711624C2 (ru) * 2017-06-30 2020-01-17 Общество с ограниченной ответственностью "ФБК" Комбинированное средство на основе нпвс, миорелаксанта и витамина

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6002385B2 (ja) * 2008-09-12 2016-10-05 クリティカル ファーマシューティカルズ リミテッドCritical Pharmaceuticals Limited 医薬組成物、医薬組成物における吸収促進剤の使用方法、及び医薬組成物の製造方法
JP5739679B2 (ja) * 2010-03-01 2015-06-24 ロート製薬株式会社 外用組成物
PE20140936A1 (es) * 2011-05-03 2014-08-06 Aponia Lab Inc Composiciones transdermicas de ibuprofeno y metodos de uso de las mismas
WO2012172413A1 (en) 2011-06-16 2012-12-20 Abbott Healthcare Pvt. Ltd. Pharmaceutical composition comprising a combination of eperisone and diclofenac and process for preparing thereof
KR101156054B1 (ko) * 2011-09-05 2012-06-20 주식회사 네비팜 안정한 에페리손 함유 서방성 의약조성물
UA119324C2 (uk) * 2013-04-02 2019-06-10 Теміс Медікер Лімітед Композиції фармацевтично активних речовин, що містять моноетиловий ефір діетиленгліколю або інші алкільні похідні
WO2016121996A1 (ja) * 2015-01-30 2016-08-04 株式会社メドレックス 水性外用剤
TR201720293A2 (tr) * 2017-12-13 2019-06-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Tolperi̇zon ve non-selekti̇f cox i̇nhi̇bi̇törü kombi̇nasyonlari
WO2020086046A2 (en) * 2018-10-26 2020-04-30 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Topical compositions comprising tolperisone and flurbiprofen combination
US20220378729A1 (en) 2019-11-06 2022-12-01 Smartech Topical, Inc. Topical formulations of cyclooxygenase inhibitors and their use
CN114939104B (zh) * 2022-06-02 2023-10-24 杭州润宠归美生物科技有限公司 一种用于减轻猫应激的外用透皮制剂、制备方法及应用
CN120919084A (zh) * 2025-08-27 2025-11-11 广州神元辉康生物医药科技有限公司 一种药物组合物及其制备方法和用途

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0295411A1 (en) * 1987-05-15 1988-12-21 Sansho Co., Ltd. Pharmaceutical preparation for percutaneous administration containing eperisone or tolperisone or a salt thereof
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
JPH0640917A (ja) * 1991-06-21 1994-02-15 Nichiban Co Ltd トルペリゾン又はエペリゾン含有ハップ剤
JP2000143510A (ja) * 1998-11-16 2000-05-23 Taisho Pharmaceut Co Ltd 外用組成物
WO2005032514A1 (en) * 2003-10-09 2005-04-14 Richter Gedeon Vegyészeti Gyár Rt. Transdermal pharmaceutical composition

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6087215A (ja) * 1983-10-19 1985-05-16 Mitsui Toatsu Chem Inc 外用薬用基材
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5252588A (en) * 1990-04-27 1993-10-12 Sekisui Kagaku Kogyo Kabushiki Kaisha Percutaneously absorbable crosslinked polyvinylpyrrolidone eperisone or tolperisone preparation
JP3525225B2 (ja) * 1992-11-09 2004-05-10 積水化学工業株式会社 エペリゾンまたはトルペリゾン経皮吸収テープ剤またはパッチ剤、およびその製造方法
IT1265001B1 (it) * 1993-12-16 1996-10-17 Zambon Spa Composizione farmaceutica per uso topico contenente acido (s)-2-(4- isobutilfenil) propionico
DE69528165T2 (de) * 1994-04-21 2003-05-15 Hisamitsu Pharmaceutical Co., Inc. Transdermal verabreichbare grundlage und daraus hergestelltes transdermal verabreichbares arzneimittel
US5846620A (en) * 1997-02-06 1998-12-08 W. R. Grace & Co.-Conn. High strength flexible film package
WO2001052823A2 (en) * 2000-01-20 2001-07-26 Noven Pharmaceuticals, Inc. Compositions to effect the release profile in the transdermal administration of drugs
US20050163831A1 (en) * 2002-08-02 2005-07-28 Hisamitsu Pharmaceutical Co., Inc. Patch for transdermal administration
KR101105612B1 (ko) * 2003-03-18 2012-01-18 히사미쓰 세이야꾸 가부시키가이샤 비스테로이드계 소염 진통제 함유 첩부제
US20070065463A1 (en) * 2003-06-20 2007-03-22 Ronald Aung-Din Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions
AT500144A1 (de) * 2004-03-05 2005-11-15 Sanochemia Pharmazeutika Ag Tolperison enthaltende, pharmazeutische zubereitung mit steuerbarer wirkstofffreisetzung zur oralen verabreichung
KR20070011469A (ko) * 2004-04-13 2007-01-24 알자 코포레이션 펜타닐계 약제의 경피전달용 장치 및 방법
AU2005267396B2 (en) * 2004-06-24 2009-09-17 Idexx Laboratories, Inc. Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
US20060004050A1 (en) * 2004-07-02 2006-01-05 Speicher Brian T Compositions and methods for the prevention or treatment of pain and other nervous system disorders
DE602005021248D1 (de) * 2004-12-17 2010-06-24 Exxonmobil Chem Patents Inc Homogenes polymerblend und artikel daraus
AT505225A1 (de) * 2007-04-26 2008-11-15 Sanochemia Pharmazeutika Ag 0erfahren zur herstellung von hoch reinem 2,4'-dimethyl-3-piperidino-propiophenon (tolperison), dieses enthaltende pharmazeutische zusammensetzungen, sowie tolperison enthaltende wirkstoffformulierungen

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0295411A1 (en) * 1987-05-15 1988-12-21 Sansho Co., Ltd. Pharmaceutical preparation for percutaneous administration containing eperisone or tolperisone or a salt thereof
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
JPH0640917A (ja) * 1991-06-21 1994-02-15 Nichiban Co Ltd トルペリゾン又はエペリゾン含有ハップ剤
JP2000143510A (ja) * 1998-11-16 2000-05-23 Taisho Pharmaceut Co Ltd 外用組成物
WO2005032514A1 (en) * 2003-10-09 2005-04-14 Richter Gedeon Vegyészeti Gyár Rt. Transdermal pharmaceutical composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200429 Thomson Scientific, London, GB; AN 2004-312695 XP002522007 & RO 118177 В (EUROPHARMACEUTICALS SA) 28 March 2003 (2003-03-28) abstract *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2711624C2 (ru) * 2017-06-30 2020-01-17 Общество с ограниченной ответственностью "ФБК" Комбинированное средство на основе нпвс, миорелаксанта и витамина

Also Published As

Publication number Publication date
HUP0700828A2 (en) 2010-01-28
HU0700828D0 (en) 2008-02-28
EA201070747A1 (ru) 2010-12-30
WO2009081217A1 (en) 2009-07-02
US20100273746A1 (en) 2010-10-28
CA2709538A1 (en) 2009-07-02
JP2011507826A (ja) 2011-03-10
EP2231116A1 (en) 2010-09-29

Similar Documents

Publication Publication Date Title
EA018536B1 (ru) Фармацевтический препарат, содержащий толперизон
RU2463038C2 (ru) Диклофенаковый гель
CN102292068B (zh) 双氯芬酸、卡马西平和苄达明的透皮递送
FI78235B (fi) Foerfarande foer framstaellning av en topisk anti-inflammatorisk komposition i gelsalvaform.
JP5989095B2 (ja) イブプロフェンの経皮組成物およびその使用方法
PT1510213E (pt) Sistemas de melhoramento de penetração e reduzida irritação incluíndo testosterona
US11413283B2 (en) Topical formulations for delivery of hedgehog inhibitor compounds and use thereof
PT2116243E (pt) Composição de gel para tratamento de micoses
US10716754B2 (en) Topical formulation
JP6025732B2 (ja) ヒストンデアセチラーゼ阻害薬のための医薬製剤
AU2009273211B2 (en) Transdermal pharmaceutical compositions comprising danazol
RU2389483C2 (ru) Химически устойчивые композиции 4-гидрокси-тамоксифена
JP2012092067A (ja) 非ステロイド性消炎鎮痛外用剤
KR20220066068A (ko) 활성 제제의 국소 전달을 위한 용매 전달 시스템
CN1909929A (zh) 消炎镇痛外用药
WO2016137411A1 (en) Topical spray composition comprising ibuprofen and lidocaine
JP2024507266A (ja) ヒドロゲル組成物、ならびに放射線によって引き起こされる皮膚損傷の予防および/または処置におけるその使用
WO2007099559A2 (en) Method of preparation for novel composition of 2-{(2,6 dichlorophenyl) amino] benzeneacetic acid carboxymethyl ester or 2-[2-[2-(2,6-dichlorophenyl) amino] phenylacetoxyacetic acid and method of its use
WO2016116909A2 (en) Non-staining topical gel compositions of nimesulide
RU2604149C2 (ru) Фармацевтическая композиция против воспаления и боли и способ ее приготовления (варианты )
JPH0696527B2 (ja) 消炎鎮痛ゲル剤
JP2025020501A (ja) ヘパリン類似物質とサリチル酸と界面活性剤とを含有する皮膚外用剤
JP2025020500A (ja) ヘパリン類似物質と第4級アンモニウム基を有する化合物とグリチルリチン酸とを含有する皮膚外用剤
JP2025020499A (ja) ヘパリン類似物質および第4級アンモニウム基を有する化合物を含有する皮膚外用剤
Sevastre et al. Influence of some dissolution enhancing agents on the pharmacokinetic profile of meloxicam delivered from hydrophilic ointments

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU