EA016804B1 - Циклические конструкты натрийуретических пептидов - Google Patents
Циклические конструкты натрийуретических пептидов Download PDFInfo
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- EA016804B1 EA016804B1 EA200802059A EA200802059A EA016804B1 EA 016804 B1 EA016804 B1 EA 016804B1 EA 200802059 A EA200802059 A EA 200802059A EA 200802059 A EA200802059 A EA 200802059A EA 016804 B1 EA016804 B1 EA 016804B1
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- EA
- Eurasian Patent Office
- Prior art keywords
- amino acid
- group
- aaa
- mmol
- derivative
- Prior art date
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- 125000004122 cyclic group Chemical group 0.000 title claims abstract description 19
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
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| US74396106P | 2006-03-30 | 2006-03-30 | |
| US74396006P | 2006-03-30 | 2006-03-30 | |
| PCT/US2007/065645 WO2007115175A2 (en) | 2006-03-30 | 2007-03-30 | Cyclic natriuretic peptide constructs |
Publications (2)
| Publication Number | Publication Date |
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| EA200802059A1 EA200802059A1 (ru) | 2009-04-28 |
| EA016804B1 true EA016804B1 (ru) | 2012-07-30 |
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| EA200802059A EA016804B1 (ru) | 2006-03-30 | 2007-03-30 | Циклические конструкты натрийуретических пептидов |
Country Status (14)
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| EP (1) | EP2001518B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5355383B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101434612B1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007233116B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0709427A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2647143A1 (cg-RX-API-DMAC7.html) |
| CO (1) | CO6140040A2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2001518T3 (cg-RX-API-DMAC7.html) |
| EA (1) | EA016804B1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2430323T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL194262A (cg-RX-API-DMAC7.html) |
| MX (1) | MX2008012663A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007115175A2 (cg-RX-API-DMAC7.html) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2007115182A2 (en) | 2006-03-30 | 2007-10-11 | Palatin Technologies, Inc. | Linear natriuretic peptide constructs |
| MX2008012663A (es) * | 2006-03-30 | 2008-10-13 | Palatin Technologies Inc | Constructos ciclicos de peptidos natriureticos. |
| US7964181B2 (en) * | 2006-03-30 | 2011-06-21 | Palatin Technologies, Inc. | Amino acid surrogates for peptidic constructs |
| US8580746B2 (en) * | 2006-03-30 | 2013-11-12 | Palatin Technologies, Inc. | Amide linkage cyclic natriuretic peptide constructs |
| BRPI0709405A2 (pt) * | 2006-03-30 | 2011-07-12 | Palatin Technologies Inc | composto lineares ou cìclicos |
| US8114844B2 (en) | 2006-03-30 | 2012-02-14 | Palatin Technologies, Inc. | Linear and cyclic melanocortin receptor-specific peptidomimetics |
| US8450285B2 (en) | 2009-06-05 | 2013-05-28 | 13Therapeutics, Inc. | Immunoregulatory peptides and methods of use |
| US9458198B1 (en) | 2009-06-26 | 2016-10-04 | Shire Orphan Therapies Gmbh | Cyclic peptide-based NPR-B agonists |
| US8546523B2 (en) * | 2009-09-25 | 2013-10-01 | Alcon Research, Ltd. | NPR-B agonists |
| TW201121995A (en) | 2009-12-18 | 2011-07-01 | Alcon Res Ltd | Novel NPR-B agonists |
| IE20100174A1 (en) * | 2010-03-25 | 2012-02-29 | Trinity College Dublin | Transdermal administration of peptides |
| WO2011133735A2 (en) * | 2010-04-21 | 2011-10-27 | Palatin Technologies, Inc. | Uses of natriuretic peptide constructs |
| WO2012138879A2 (en) | 2011-04-06 | 2012-10-11 | 13Therapeutics, Inc. | Peptides for the treatment of hearing |
| KR101867026B1 (ko) | 2011-12-28 | 2018-07-20 | 대우조선해양 주식회사 | 밸러스트 수 처리 시스템의 미처리 수 처리 모듈 |
| TWI865542B (zh) | 2019-06-12 | 2024-12-11 | 瑞士商諾華公司 | 利鈉肽受體1抗體及使用方法 |
| CA3150733A1 (en) * | 2019-08-12 | 2021-02-18 | Biomarin Pharmaceutical Inc. | Hydrophobic peptide salts for extended release compositions |
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- 2007-03-30 EP EP07759833.2A patent/EP2001518B1/en active Active
- 2007-03-30 AU AU2007233116A patent/AU2007233116B2/en not_active Ceased
- 2007-03-30 DK DK07759833.2T patent/DK2001518T3/da active
- 2007-03-30 EA EA200802059A patent/EA016804B1/ru not_active IP Right Cessation
- 2007-03-30 BR BRPI0709427-2A patent/BRPI0709427A2/pt not_active IP Right Cessation
- 2007-03-30 ES ES07759833T patent/ES2430323T3/es active Active
- 2007-03-30 WO PCT/US2007/065645 patent/WO2007115175A2/en not_active Ceased
- 2007-03-30 JP JP2009503312A patent/JP5355383B2/ja not_active Expired - Fee Related
- 2007-03-30 CA CA002647143A patent/CA2647143A1/en not_active Abandoned
- 2007-03-30 US US11/694,260 patent/US7622440B2/en active Active
- 2007-03-30 KR KR1020087026715A patent/KR101434612B1/ko not_active Expired - Fee Related
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- 2008-09-22 IL IL194262A patent/IL194262A/en not_active IP Right Cessation
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Also Published As
| Publication number | Publication date |
|---|---|
| IL194262A (en) | 2014-05-28 |
| BRPI0709427A2 (pt) | 2011-07-12 |
| MX2008012663A (es) | 2008-10-13 |
| CA2647143A1 (en) | 2007-10-11 |
| DK2001518T3 (da) | 2013-10-07 |
| US7622440B2 (en) | 2009-11-24 |
| EP2001518A4 (en) | 2009-11-04 |
| US20100075895A1 (en) | 2010-03-25 |
| KR20090025196A (ko) | 2009-03-10 |
| JP2009532384A (ja) | 2009-09-10 |
| EP2001518A2 (en) | 2008-12-17 |
| KR101434612B1 (ko) | 2014-08-26 |
| AU2007233116B2 (en) | 2013-05-09 |
| EP2001518B1 (en) | 2013-07-10 |
| WO2007115175A2 (en) | 2007-10-11 |
| WO2007115175A3 (en) | 2008-12-11 |
| EA200802059A1 (ru) | 2009-04-28 |
| JP5355383B2 (ja) | 2013-11-27 |
| CO6140040A2 (es) | 2010-03-19 |
| US20070265206A1 (en) | 2007-11-15 |
| US8580747B2 (en) | 2013-11-12 |
| AU2007233116A1 (en) | 2007-10-11 |
| ES2430323T3 (es) | 2013-11-20 |
| HK1134022A1 (en) | 2010-04-16 |
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