EA016206B1 - Композиция и способ лечения воспалительных расстройств - Google Patents

Композиция и способ лечения воспалительных расстройств Download PDF

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Publication number
EA016206B1
EA016206B1 EA200901289A EA200901289A EA016206B1 EA 016206 B1 EA016206 B1 EA 016206B1 EA 200901289 A EA200901289 A EA 200901289A EA 200901289 A EA200901289 A EA 200901289A EA 016206 B1 EA016206 B1 EA 016206B1
Authority
EA
Eurasian Patent Office
Prior art keywords
tetracycline
tetracyclines
inflammatory
compositions
calcium
Prior art date
Application number
EA200901289A
Other languages
English (en)
Russian (ru)
Other versions
EA200901289A1 (ru
Inventor
Петр Хомчинский
Original Assignee
Моликьюлар Рисерч Сентер, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Моликьюлар Рисерч Сентер, Инк. filed Critical Моликьюлар Рисерч Сентер, Инк.
Publication of EA200901289A1 publication Critical patent/EA200901289A1/ru
Publication of EA016206B1 publication Critical patent/EA016206B1/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
EA200901289A 2007-03-23 2008-03-20 Композиция и способ лечения воспалительных расстройств EA016206B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89656407P 2007-03-23 2007-03-23
PCT/US2008/057646 WO2008118744A1 (en) 2007-03-23 2008-03-20 Anti-inflammatory compositions comprising tetracyclines and use thereof in therapy

Publications (2)

Publication Number Publication Date
EA200901289A1 EA200901289A1 (ru) 2010-02-26
EA016206B1 true EA016206B1 (ru) 2012-03-30

Family

ID=39651298

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200901289A EA016206B1 (ru) 2007-03-23 2008-03-20 Композиция и способ лечения воспалительных расстройств

Country Status (9)

Country Link
US (1) US20080233206A1 (enExample)
EP (1) EP2125018A1 (enExample)
JP (1) JP5395052B2 (enExample)
KR (2) KR20130137696A (enExample)
CN (2) CN102688492A (enExample)
AP (1) AP2657A (enExample)
AU (1) AU2008231033B2 (enExample)
EA (1) EA016206B1 (enExample)
WO (1) WO2008118744A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2683645C1 (ru) * 2013-12-11 2019-04-01 Могон Фармасьютикалс Сагл Терапевтические системы с модифицированным высвобождением для перорального введения ментола в лечении кишечных расстройств

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AU2004261143B2 (en) 2003-07-25 2009-11-05 Allergan Pharmaceuticals International Limited A doxycycline metal complex in a solid dosage form
EP1855690B1 (en) * 2005-01-21 2016-06-01 Warner Chilcott Company, LLC A tetracycline metal complex in a solid dosage form
SG185513A1 (en) * 2010-05-12 2012-12-28 Rempex Pharmaceuticals Inc Tetracycline compositions
US9119793B1 (en) 2011-06-28 2015-09-01 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for doxycycline
CN103536607A (zh) * 2012-07-10 2014-01-29 邵金辉 土霉素,普罗帕酮和安乃近的抗肿瘤作用
PT106679B (pt) * 2012-11-27 2015-03-25 Hovione Farmaciencia Sa Formulações tópicas de tetraciclinas, sua preparação e usos
US10842802B2 (en) 2013-03-15 2020-11-24 Medicis Pharmaceutical Corporation Controlled release pharmaceutical dosage forms
WO2015153864A2 (en) * 2014-04-02 2015-10-08 Hopkins Patricia T Methods for treating inflammatory conditions
CN103933539B (zh) * 2014-04-16 2017-01-11 西北农林科技大学 一种含有四环素的药物组合物及其应用
KR20170134514A (ko) 2015-03-23 2017-12-06 바이오팜엑스 인코포레이티드 피부과 사용을 위한 약학 테트라사이클린 조성물
CN105998037A (zh) * 2016-06-16 2016-10-12 汕头大学 多西环素在制备治疗或预防衰老性疾病的药物中的用途
CO2017001953A1 (es) * 2017-02-27 2018-08-31 Corporacion Univ Lasallista Método de encapsulación de tetraciclinas
DK3873432T3 (da) * 2018-10-29 2022-12-19 Fraunhofer Ges Forschung Tetracyclinkomplekser med vedvarende aktivitet
CN110169973A (zh) * 2019-06-11 2019-08-27 贾树森 一种用于颈椎康复的外用药物组合物
CN111870607A (zh) * 2020-07-09 2020-11-03 温州医科大学 盐酸米诺环素作为制备治疗自身免疫性葡萄膜炎药物的应用及其治疗方法
KR102855121B1 (ko) * 2021-12-17 2025-09-04 주식회사 케이씨앤씨 클로르테트라사이클린을 포함하는 고양이 전염성 복막염 치료용 조성물
CN116655491B (zh) * 2023-05-12 2025-01-28 常州大学 一种多功能抗菌纳米材料TCFNPs及其制备方法和应用

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US2766124A (en) * 1954-05-25 1956-10-09 American Cyanamid Co Antibiotic-containing ice composition
US2806789A (en) * 1954-09-10 1957-09-17 American Cyanamid Co Enhancement of therapeutic efficacy of antibiotics
GB894619A (en) * 1959-09-11 1962-04-26 Pfizer & Co C Stabilized liquid preparations comprising tetracycline antibiotics
GB901107A (en) * 1959-06-29 1962-07-11 Pfizer Therapeutic composition and method of preparing same
GB901209A (en) * 1957-10-23 1962-07-18 Pfizer & Co C 6-deoxytetracyclines and compositions containing same
DE1467749A1 (de) * 1963-05-29 1968-12-05 American Cyanamid Co Verfahren zur Herstellung von stabilen Tetracyclinpraeparaten
US4060605A (en) * 1973-09-28 1977-11-29 Ankerfarm, S.P.A. Water-soluble derivative of 6-deoxy-tetracyclines
US4126680A (en) * 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
EP0310814A2 (en) * 1987-10-06 1989-04-12 American Cyanamid Company Novel controlled release formulations of tetracycline compounds
EP0327295A2 (en) * 1988-02-01 1989-08-09 F.H. FAULDING & CO. LTD. Tetracycline dosage form
US20030130240A1 (en) * 2001-04-05 2003-07-10 Ashley Robert A. Methods of treating acne

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AU2004261143B2 (en) * 2003-07-25 2009-11-05 Allergan Pharmaceuticals International Limited A doxycycline metal complex in a solid dosage form
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EP1855690B1 (en) * 2005-01-21 2016-06-01 Warner Chilcott Company, LLC A tetracycline metal complex in a solid dosage form
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* Cited by examiner, † Cited by third party
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US2736725A (en) * 1954-03-11 1956-02-28 American Cyanamid Co Complexes of tetracycline antibiotics and preparation of same
US2766124A (en) * 1954-05-25 1956-10-09 American Cyanamid Co Antibiotic-containing ice composition
US2806789A (en) * 1954-09-10 1957-09-17 American Cyanamid Co Enhancement of therapeutic efficacy of antibiotics
GB901209A (en) * 1957-10-23 1962-07-18 Pfizer & Co C 6-deoxytetracyclines and compositions containing same
GB901107A (en) * 1959-06-29 1962-07-11 Pfizer Therapeutic composition and method of preparing same
GB894619A (en) * 1959-09-11 1962-04-26 Pfizer & Co C Stabilized liquid preparations comprising tetracycline antibiotics
DE1467749A1 (de) * 1963-05-29 1968-12-05 American Cyanamid Co Verfahren zur Herstellung von stabilen Tetracyclinpraeparaten
US4060605A (en) * 1973-09-28 1977-11-29 Ankerfarm, S.P.A. Water-soluble derivative of 6-deoxy-tetracyclines
US4126680A (en) * 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
EP0310814A2 (en) * 1987-10-06 1989-04-12 American Cyanamid Company Novel controlled release formulations of tetracycline compounds
EP0327295A2 (en) * 1988-02-01 1989-08-09 F.H. FAULDING & CO. LTD. Tetracycline dosage form
US20030130240A1 (en) * 2001-04-05 2003-07-10 Ashley Robert A. Methods of treating acne

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Title
PRUZANSKI ET AL.: "Chemically modified non-antimicrobial tetracyclines inhibit activity of phospholipases A2", CA, 1 January 1990 (1990-01-01), XP002246102, the whole document *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2683645C1 (ru) * 2013-12-11 2019-04-01 Могон Фармасьютикалс Сагл Терапевтические системы с модифицированным высвобождением для перорального введения ментола в лечении кишечных расстройств

Also Published As

Publication number Publication date
CN101678108A (zh) 2010-03-24
CN102688492A (zh) 2012-09-26
AP2657A (en) 2013-05-07
EA200901289A1 (ru) 2010-02-26
AU2008231033B2 (en) 2012-08-30
US20080233206A1 (en) 2008-09-25
WO2008118744A1 (en) 2008-10-02
EP2125018A1 (en) 2009-12-02
KR20130137696A (ko) 2013-12-17
JP5395052B2 (ja) 2014-01-22
JP2010522240A (ja) 2010-07-01
AU2008231033A1 (en) 2008-10-02
AP2009004979A0 (en) 2009-10-31
KR20090122994A (ko) 2009-12-01

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