EA010294B1 - Композиции на основе производных липопептидных антибиотиков и способы их применения - Google Patents

Композиции на основе производных липопептидных антибиотиков и способы их применения Download PDF

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Publication number
EA010294B1
EA010294B1 EA200600280A EA200600280A EA010294B1 EA 010294 B1 EA010294 B1 EA 010294B1 EA 200600280 A EA200600280 A EA 200600280A EA 200600280 A EA200600280 A EA 200600280A EA 010294 B1 EA010294 B1 EA 010294B1
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EA
Eurasian Patent Office
Prior art keywords
acid
substituted
amphomycin
compound
amino acid
Prior art date
Application number
EA200600280A
Other languages
English (en)
Russian (ru)
Other versions
EA200600280A1 (ru
Inventor
Дэйл Р. Камерон
Винсент А. Бойд
Ричард А. Лиз
Вильям В. Курран
Дональд Б. Бордерс
Паоло В.М. Сгарби
Ширли А. Вакович-Сгарби
Мэтью Нодвелл
Юхен Чен
Кьюи Джиа
Доминик Дугорд
Original Assignee
Майджиникс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Майджиникс, Инк. filed Critical Майджиникс, Инк.
Publication of EA200600280A1 publication Critical patent/EA200600280A1/ru
Publication of EA010294B1 publication Critical patent/EA010294B1/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EA200600280A 2003-07-17 2004-06-28 Композиции на основе производных липопептидных антибиотиков и способы их применения EA010294B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48833103P 2003-07-17 2003-07-17
US56491204P 2004-04-23 2004-04-23
PCT/US2004/021039 WO2005000878A2 (en) 2003-06-26 2004-06-28 Compositions of lipopeptide antibiotic derivatives and methods of use thereof

Publications (2)

Publication Number Publication Date
EA200600280A1 EA200600280A1 (ru) 2006-10-27
EA010294B1 true EA010294B1 (ru) 2008-08-29

Family

ID=36203969

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200600280A EA010294B1 (ru) 2003-07-17 2004-06-28 Композиции на основе производных липопептидных антибиотиков и способы их применения

Country Status (11)

Country Link
US (1) US7868135B2 (https=)
EP (2) EP1656390A2 (https=)
JP (1) JP2007536200A (https=)
CN (1) CN1839150A (https=)
AU (1) AU2004252174A1 (https=)
CA (1) CA2530063A1 (https=)
EA (1) EA010294B1 (https=)
IL (1) IL172647A0 (https=)
NZ (1) NZ544750A (https=)
WO (1) WO2005000878A2 (https=)
ZA (1) ZA200600008B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
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RU2762182C1 (ru) * 2020-12-08 2021-12-16 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Гауземицины А и В - гликолипопептидные антибактериальные антибиотики и способ их получения

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RU2008132757A (ru) * 2006-02-09 2010-03-20 Елевансе Реневал Сайенсез, Инк. (US) Антибактериальные составы, способы и системы
GB0821540D0 (en) * 2008-11-25 2008-12-31 Merlion Pharmaceuticals Pte Ltd Lipopeptide compounds and their use
JP5719783B2 (ja) 2009-02-16 2015-05-20 セレニス セラピューティクス ホールディング エスアー アポリポタンパクa−i模倣物
DE102009060102A1 (de) * 2009-12-21 2011-06-22 Martin-Luther-Universität Halle-Wittenberg, 06108 Derivatisierungsreagenzien zur tandem-massenspektrometrischen Quantifizierung von Proteinen
CN102939095A (zh) * 2010-03-09 2013-02-20 默沙东公司 增强β-内酰胺抗菌药物的活性的桥联脂糖肽类
ES2374779B1 (es) * 2010-03-10 2012-12-27 Universidad De Barcelona Compuestos péptidicos útiles como agentes antibacterianos.
US9428845B1 (en) 2010-12-28 2016-08-30 Warp Drive Bio, Inc. Identifying new therapeutic agents
TWI642684B (zh) * 2011-05-27 2018-12-01 Rqx製藥股份有限公司 廣效性抗生素
US10501493B2 (en) 2011-05-27 2019-12-10 Rqx Pharmaceuticals, Inc. Broad spectrum antibiotics
EP2703410B1 (en) * 2012-08-28 2015-10-14 Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie Jagaricin, derivatives, and uses thereof
KR20150088292A (ko) 2012-11-21 2015-07-31 알큐엑스 파마슈티컬스, 인크. 광범위한 마크로사이클릭 항생제
WO2015179441A2 (en) 2014-05-20 2015-11-26 Rqx Pharmaceuticals, Inc. Macrocyclic broad spectrum antibiotics
US9856292B2 (en) * 2014-11-14 2018-01-02 Bristol-Myers Squibb Company Immunomodulators
CN104557743A (zh) * 2014-12-02 2015-04-29 南京邮电大学 一类包含不饱和脂肪酸结构的抗白色念珠菌药物及其制备方法
EP3247378B8 (en) 2015-01-09 2023-08-23 Revolution Medicines, Inc. Macrocyclic compounds that participate in cooperative binding and medical uses thereof
CN104817619B (zh) * 2015-04-23 2018-07-17 浙江大学 抗菌化合物及其应用
CN105231000B (zh) * 2015-09-25 2020-01-07 广东海洋大学 一种利用水产品下脚料生产抗菌营养复合型饲料添加剂的方法
US11072635B2 (en) 2015-11-20 2021-07-27 Rqx Pharmaceuticals, Inc. Macrocyclic broad spectrum antibiotics
CA3058953A1 (en) * 2017-04-05 2018-10-11 Revolution Medicines, Inc. Compounds that participate in cooperative binding and uses thereof
CN109593808B (zh) * 2017-09-30 2022-10-04 上海医药工业研究院 达托霉素发酵培养基及其制备方法
JP7296636B2 (ja) * 2018-07-20 2023-06-23 藤本化学製品株式会社 アルコキシフェニル誘導体、ヌクレオシド保護体およびヌクレオチド保護体、オリゴヌクレオチド製造方法、ならびに、置換基除去方法
JP6770553B2 (ja) * 2018-07-20 2020-10-14 藤本化学製品株式会社 アルコキシフェニル誘導体、ヌクレオシド保護体およびヌクレオチド保護体、オリゴヌクレオチド製造方法、ならびに、置換基除去方法
EP3833329A1 (en) * 2018-08-06 2021-06-16 Khan, Khalid Antimicrobial formulations comprising vancomycin or tobramycin
CN111434775B (zh) * 2019-01-11 2022-12-06 上海医药工业研究院 一种发酵制备达托霉素的方法
JP7078807B2 (ja) 2019-05-28 2022-05-31 エフ.ホフマン-ラ ロシュ アーゲー 大環状広域スペクトル抗生物質
CN112625106B (zh) * 2021-01-13 2023-03-31 兰州大学 一种抗菌多肽化合物、合成方法及其应用

Citations (4)

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US5629288A (en) * 1994-03-30 1997-05-13 Hoechst Aktiengesellschaft Lipopeptide derivatives, a process for their preparation and their use
US6194383B1 (en) * 1993-06-08 2001-02-27 Hoechst Aktiengesellschaft Lipopeptides from actinoplanes sp. with pharmacological action, process for their production and the use thereof
WO2002005837A1 (en) * 2000-07-17 2002-01-24 Intrabiotics Pharmaceuticals, Inc. Antimicrobial sulfonamide derivatives of lipopeptide antibiotics
WO2003057724A1 (en) * 2002-01-03 2003-07-17 Micrologix Biotech Inc. Dab9 DERIVATIVES OF LIPOPEPTIDE ANTIBIOTICS AND METHODS OF MAKING AND USING THE SAME

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US3057779A (en) 1960-03-14 1962-10-09 American Cyanamid Co Antibiotic and production thereof
US3639582A (en) 1967-04-14 1972-02-01 Zaidan Hojin Biseibutsu Antibiotic laspartomycin
DE1800363A1 (de) 1967-10-04 1969-07-03 Shionogi & Co Tsushimycin und seine Herstellung
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US4977083A (en) 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
US5028590A (en) 1988-04-11 1991-07-02 Eli Lilly And Company Derivatives of A54145 cyclic peptides
US4994270A (en) 1988-04-11 1991-02-19 Eli Lilly And Company A54145 antibiotics and process for their production
EP1666587A1 (en) 1996-06-13 2006-06-07 Astellas Pharma Inc. Cyclic lipopeptide acylase
DE19807972A1 (de) 1998-02-25 1999-08-26 Hoechst Marion Roussel De Gmbh Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung
US6716962B2 (en) 2000-07-17 2004-04-06 Micrologix Biotech Inc. Extractive purification of lipopeptide antibiotics
US6750199B2 (en) 2000-07-17 2004-06-15 Micrologix Biotech Inc. Antimicrobial sulfonamide derivatives of lipopeptide antibiotics

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194383B1 (en) * 1993-06-08 2001-02-27 Hoechst Aktiengesellschaft Lipopeptides from actinoplanes sp. with pharmacological action, process for their production and the use thereof
US5629288A (en) * 1994-03-30 1997-05-13 Hoechst Aktiengesellschaft Lipopeptide derivatives, a process for their preparation and their use
WO2002005837A1 (en) * 2000-07-17 2002-01-24 Intrabiotics Pharmaceuticals, Inc. Antimicrobial sulfonamide derivatives of lipopeptide antibiotics
WO2003057724A1 (en) * 2002-01-03 2003-07-17 Micrologix Biotech Inc. Dab9 DERIVATIVES OF LIPOPEPTIDE ANTIBIOTICS AND METHODS OF MAKING AND USING THE SAME

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2762182C1 (ru) * 2020-12-08 2021-12-16 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт по изысканию новых антибиотиков имени Г.Ф. Гаузе" Гауземицины А и В - гликолипопептидные антибактериальные антибиотики и способ их получения

Also Published As

Publication number Publication date
JP2007536200A (ja) 2007-12-13
EP2147925A1 (en) 2010-01-27
AU2004252174A1 (en) 2005-01-06
ZA200600008B (en) 2007-09-26
EP1656390A2 (en) 2006-05-17
WO2005000878A2 (en) 2005-01-06
US7868135B2 (en) 2011-01-11
NZ544750A (en) 2009-06-26
EA200600280A1 (ru) 2006-10-27
CA2530063A1 (en) 2005-01-06
US20050153876A1 (en) 2005-07-14
WO2005000878A3 (en) 2005-06-16
WO2005000878A8 (en) 2006-06-08
IL172647A0 (en) 2006-04-10
CN1839150A (zh) 2006-09-27

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY RU