EA005762B1 - Спиро-пиримидин-2,4,6-трионовые ингибиторы металлопротеиназы - Google Patents
Спиро-пиримидин-2,4,6-трионовые ингибиторы металлопротеиназы Download PDFInfo
- Publication number
- EA005762B1 EA005762B1 EA200300306A EA200300306A EA005762B1 EA 005762 B1 EA005762 B1 EA 005762B1 EA 200300306 A EA200300306 A EA 200300306A EA 200300306 A EA200300306 A EA 200300306A EA 005762 B1 EA005762 B1 EA 005762B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pyridin
- disorders
- triazaspiro
- compounds
- mmp
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Oncology (AREA)
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- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Cardiology (AREA)
- Virology (AREA)
- Ophthalmology & Optometry (AREA)
- Pregnancy & Childbirth (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24338900P | 2000-10-26 | 2000-10-26 | |
| PCT/IB2001/001986 WO2002034753A2 (en) | 2000-10-26 | 2001-10-23 | Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200300306A1 EA200300306A1 (ru) | 2003-08-28 |
| EA005762B1 true EA005762B1 (ru) | 2005-06-30 |
Family
ID=22918584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200300306A EA005762B1 (ru) | 2000-10-26 | 2001-10-23 | Спиро-пиримидин-2,4,6-трионовые ингибиторы металлопротеиназы |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP1332146A2 (es) |
| JP (1) | JP2004518635A (es) |
| KR (1) | KR20040004412A (es) |
| CN (1) | CN1501937A (es) |
| AP (1) | AP2001002318A0 (es) |
| AR (1) | AR035069A1 (es) |
| AU (1) | AU2002210813A1 (es) |
| BG (1) | BG107653A (es) |
| BR (1) | BR0114913A (es) |
| CA (1) | CA2425283A1 (es) |
| CZ (1) | CZ20031083A3 (es) |
| EA (1) | EA005762B1 (es) |
| EC (1) | ECSP034567A (es) |
| EE (1) | EE200300196A (es) |
| GT (1) | GT200100213A (es) |
| HN (1) | HN2001000244A (es) |
| HR (1) | HRP20030332A2 (es) |
| HU (1) | HUP0301577A3 (es) |
| IL (1) | IL154948A0 (es) |
| IS (1) | IS6762A (es) |
| MA (1) | MA26957A1 (es) |
| MX (1) | MXPA03003735A (es) |
| NO (1) | NO20031853L (es) |
| OA (1) | OA12529A (es) |
| PA (1) | PA8531401A1 (es) |
| PE (1) | PE20020589A1 (es) |
| PL (1) | PL366201A1 (es) |
| SK (1) | SK4972003A3 (es) |
| SV (1) | SV2003000705A (es) |
| TN (1) | TNSN01149A1 (es) |
| WO (1) | WO2002034753A2 (es) |
| ZA (1) | ZA200302190B (es) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9993462B2 (en) | 2014-06-09 | 2018-06-12 | Chugai Seiyaku Kabushiki Kaisha | Hydantoin derivative-containing pharmaceutical composition |
| RU2678984C2 (ru) * | 2012-12-10 | 2019-02-05 | Чугаи Сейяку Кабусики Кайся | Производное гидантоина |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA03004920A (es) | 2001-02-14 | 2003-09-05 | Warner Lambert Co | Pirimidinas inhibidoras de metaloproteinasas de matriz. |
| DOP2002000333A (es) | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz |
| DOP2002000332A (es) | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Inhibidores de piridina de metaloproteinasas de la matriz |
| PA8539501A1 (es) | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Compuestos triazolo como inhibidores de mmp |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2678984C2 (ru) * | 2012-12-10 | 2019-02-05 | Чугаи Сейяку Кабусики Кайся | Производное гидантоина |
| US9993462B2 (en) | 2014-06-09 | 2018-06-12 | Chugai Seiyaku Kabushiki Kaisha | Hydantoin derivative-containing pharmaceutical composition |
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