DZ587A1 - 4-Aminoalkyl-2(3H) inolones. - Google Patents
4-Aminoalkyl-2(3H) inolones.Info
- Publication number
- DZ587A1 DZ587A1 DZ847014A DZ847014A DZ587A1 DZ 587 A1 DZ587 A1 DZ 587A1 DZ 847014 A DZ847014 A DZ 847014A DZ 847014 A DZ847014 A DZ 847014A DZ 587 A1 DZ587 A1 DZ 587A1
- Authority
- DZ
- Algeria
- Prior art keywords
- inolones
- aminoalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/447,564 US4452808A (en) | 1982-12-07 | 1982-12-07 | 4-Aminoalkyl-2(3H)-indolones |
Publications (1)
Publication Number | Publication Date |
---|---|
DZ587A1 true DZ587A1 (fr) | 2004-09-13 |
Family
ID=23776840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DZ847014A DZ587A1 (fr) | 1982-12-07 | 1984-12-07 | 4-Aminoalkyl-2(3H) inolones. |
Country Status (27)
Country | Link |
---|---|
US (1) | US4452808A (fr) |
EP (1) | EP0113964B1 (fr) |
JP (1) | JPS59112964A (fr) |
KR (1) | KR910001042B1 (fr) |
AU (1) | AU560170B2 (fr) |
BR (1) | BR1100036A (fr) |
CA (1) | CA1208650A (fr) |
CY (1) | CY1497A (fr) |
CZ (1) | CZ398191A3 (fr) |
DE (1) | DE3367090D1 (fr) |
DK (1) | DK156514C (fr) |
DZ (1) | DZ587A1 (fr) |
EG (1) | EG16556A (fr) |
ES (2) | ES8600239A1 (fr) |
FI (1) | FI77849C (fr) |
GR (1) | GR79121B (fr) |
HK (1) | HK82089A (fr) |
IE (1) | IE56347B1 (fr) |
IL (1) | IL70311A (fr) |
LU (1) | LU90097I2 (fr) |
NL (1) | NL970005I2 (fr) |
NO (2) | NO160135C (fr) |
NZ (1) | NZ206344A (fr) |
PH (1) | PH22067A (fr) |
PT (1) | PT77739B (fr) |
ZA (1) | ZA839094B (fr) |
ZW (1) | ZW25883A1 (fr) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4588740A (en) * | 1982-12-07 | 1986-05-13 | Smithkline Beckman Corporation | Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones |
US4657929A (en) * | 1983-10-25 | 1987-04-14 | Fisons Plc | Compounds |
US4554284A (en) * | 1984-09-12 | 1985-11-19 | Smithkline Beckman Corporation | 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones |
GB8621040D0 (en) * | 1986-08-30 | 1986-10-08 | Smith Kline French Lab | Process |
GB8712073D0 (en) * | 1987-05-21 | 1987-06-24 | Smith Kline French Lab | Medicament |
GB8714371D0 (en) * | 1987-06-19 | 1987-07-22 | Smith Kline French Lab | Process |
GB9008605D0 (en) * | 1990-04-17 | 1990-06-13 | Smith Kline French Lab | Process |
GB9015095D0 (en) * | 1990-07-09 | 1990-08-29 | Smith Kline French Lab | Therapeutic method |
IE914003A1 (en) * | 1990-11-20 | 1992-05-20 | Astra Pharma Prod | Biologically Active Amines |
JPH07506823A (ja) * | 1992-05-18 | 1995-07-27 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 記憶障害,性的機能不全およびパーキンソン氏病の治療のためのインドロン誘導体の使用 |
GB9300309D0 (en) * | 1993-01-08 | 1993-03-03 | Smithkline Beecham Plc | Process |
TW356468B (en) * | 1995-09-15 | 1999-04-21 | Astra Pharma Prod | Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same |
US5807570A (en) * | 1995-09-29 | 1998-09-15 | Cygnus, Inc. | Transdermal administration of ropinirole and analogs thereof |
GB9526511D0 (en) * | 1995-12-23 | 1996-02-28 | Astra Pharma Prod | Pharmaceutically active compounds |
CN1234024A (zh) * | 1996-08-27 | 1999-11-03 | 美国家用产品公司 | 4-氨基乙氧基吲哚衍生物 |
EP1073636A1 (fr) * | 1998-04-13 | 2001-02-07 | American Home Products Corporation | 4-amino-(ethylamino)-oxindoles utilises comme agonistes des autorecepteurs de la dopamine |
US6218421B1 (en) * | 1999-07-01 | 2001-04-17 | Smithkline Beecham P.L.C. | Method of promoting smoking cessation |
AR030557A1 (es) | 2000-04-14 | 2003-08-27 | Jagotec Ag | Una tableta en multicapa de liberacion controlada y metodo de tratamiento |
US6277875B1 (en) * | 2000-07-17 | 2001-08-21 | Andrew J. Holman | Use of dopamine D2/D3 receptor agonists to treat fibromyalgia |
DE10041478A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
US20020165246A1 (en) * | 2001-03-05 | 2002-11-07 | Andrew Holman | Administration of sleep restorative agents |
FR2821843B1 (fr) * | 2001-03-12 | 2003-05-09 | Servier Lab | Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US20030068356A1 (en) * | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
PT1545546E (pt) * | 2002-09-13 | 2007-07-02 | Motac Neuroscience Ltd | Tratamento da discinesia com 2, 3-benzodiazepinas |
CN100502856C (zh) * | 2002-09-17 | 2009-06-24 | 默塔克神经科学有限公司 | 运动障碍的治疗 |
ES2237307B1 (es) | 2003-10-14 | 2006-11-01 | Urquima, S.A. | Procedimiento para la preparacion de ropinirol. |
WO2005074387A2 (fr) * | 2003-12-30 | 2005-08-18 | Sun Pharmaceutical Industries Limited | Nouvelles formes cristallines d'hydrochlorure de 4-[2-di-n-propylamino)ethyl]-2 (3h)- indolone |
US7378439B2 (en) * | 2004-01-20 | 2008-05-27 | Usv, Ltd. | Process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride |
WO2005105741A1 (fr) * | 2004-02-11 | 2005-11-10 | Sun Pharmaceutical Industries Limited | Hydrochlorure de 4-[2-(di-n-propylamino)ethyl]-2(3h)-indolone sensiblement pur |
WO2005080333A1 (fr) * | 2004-02-19 | 2005-09-01 | Torrent Pharmaceuticals Ltd | Processus de purification de ropinirole |
PT1751106E (pt) * | 2004-05-11 | 2009-02-10 | Egis Gyogyszergyar Nyrt | Derivados de piperazina de alquil-oxindoles |
HUP0400953A3 (en) * | 2004-05-11 | 2008-02-28 | Egis Gyogyszergyar Nyilvanosan | Piperazine derivatives of alkyl-oxindoles, pharmaceutical compositions containing them, process for producing them and their use |
US20050267096A1 (en) * | 2004-05-26 | 2005-12-01 | Pfizer Inc | New indazole and indolone derivatives and their use pharmaceuticals |
US20050288270A1 (en) * | 2004-05-27 | 2005-12-29 | Pfizer Inc | New aminopyridine derivatives and their use as pharmaceuticals |
JP2008533193A (ja) * | 2005-03-21 | 2008-08-21 | ファイザー・リミテッド | オキシトシン拮抗薬としての置換トリアゾール誘導体 |
CN100457711C (zh) * | 2005-06-27 | 2009-02-04 | 上海奥博生物医药技术有限公司 | 2-甲基-3-硝基苯基烷基胺衍生物或其盐的制备方法 |
WO2007010557A2 (fr) * | 2005-07-22 | 2007-01-25 | Ind-Swift Laboratorie Limted | Methode de preparation de ropinirole tres pur |
CA2645599A1 (fr) | 2006-03-29 | 2007-10-04 | Alembic Limited | Procede de purification du chlorhydrate de ropinirole |
PT2010184E (pt) * | 2006-04-06 | 2013-04-03 | Nupathe Inc | Implantes para o tratamento dos estados associados à dopamina |
US20070254941A1 (en) * | 2006-04-21 | 2007-11-01 | Glenmark Pharmaceuticals Limited | Subtantially pure ropinirole hydrochloride, polymorphic form of ropinirole and process for their preparation |
CN100457732C (zh) * | 2006-05-25 | 2009-02-04 | 药源药物化学(上海)有限公司 | 罗匹尼罗的制备方法 |
TW200815045A (en) * | 2006-06-29 | 2008-04-01 | Jazz Pharmaceuticals Inc | Pharmaceutical compositions of ropinirole and methods of use thereof |
WO2008001204A2 (fr) * | 2006-06-29 | 2008-01-03 | Antares Pharma Ipl Ag | Compositions transdermiques de pramipexole présentant des propriétés de perméation améliorées |
ATE535243T1 (de) * | 2007-05-11 | 2011-12-15 | Santen Pharmaceutical Co Ltd | Prophylaktisches oder therapeutisches mittel für posteriore augenerkrankung mit selektivem nicht- ergot-d2-rezeptoragonist als wirkstoff |
US20090076124A1 (en) * | 2007-09-14 | 2009-03-19 | Protia, Llc | Deuterium-enriched ropinirole |
US20090247537A1 (en) * | 2008-03-25 | 2009-10-01 | William Dale Overfield | Methods for preventing or treating bruxism using dopaminergic agents |
CN101574341B (zh) * | 2008-05-05 | 2012-12-19 | 北京德众万全医药科技有限公司 | 一种罗匹尼罗的口服固体药物组合物 |
WO2010023693A2 (fr) * | 2008-09-01 | 2010-03-04 | Lupin Limited | Nouvelles compositions de ropinirole à libération contrôlée |
WO2010035245A2 (fr) | 2008-09-29 | 2010-04-01 | Wockhardt Research Centre | Forme posologique à libération prolongée de ropinirole |
WO2010060070A2 (fr) * | 2008-11-24 | 2010-05-27 | Auspex Pharmaceuticals, Inc. | Modulateurs à base d'indolinone du récepteur de la dopamine |
KR101709361B1 (ko) | 2009-05-21 | 2017-02-22 | 히사미쓰 세이야꾸 가부시키가이샤 | 경피 흡수 제제 |
AU2009356855A1 (en) * | 2009-12-16 | 2012-08-09 | Pharmathen S.A. | Process for the preparation of Ropinirole and salts thereof |
CN108186611A (zh) | 2010-04-30 | 2018-06-22 | 帝国制药美国公司 | 丙炔基氨基茚满透皮组合物 |
CN101891641B (zh) * | 2010-07-27 | 2015-06-10 | 北京华禧联合科技发展有限公司 | 盐酸罗匹尼罗关键中间体的稳定形态及其制备 |
TWI537274B (zh) | 2011-03-14 | 2016-06-11 | 橘生藥品工業股份有限公司 | 新穎之八氫噻吩并喹啉衍生物、含有其之醫藥組成物及該等之用途 |
JP5906302B2 (ja) | 2011-03-24 | 2016-04-20 | テイコク ファーマ ユーエスエー インコーポレーテッド | 作用剤層および作用剤変換層を含む経皮組成物 |
JP5913614B2 (ja) | 2011-11-09 | 2016-04-27 | テイコク ファーマ ユーエスエー インコーポレーテッド | 皮膚新生物の処置方法 |
WO2014070622A1 (fr) | 2012-11-02 | 2014-05-08 | Teikoku Pharma Usa, Inc. | Compositions transdermiques de propynylaminoindane |
WO2014092006A1 (fr) | 2012-12-10 | 2014-06-19 | キッセイ薬品工業株式会社 | Nouveau dérivé d'octahydropyridoquinazoline, composition pharmaceutique le contenant, et utilisations pour ledit dérivé et ladite composition |
US9155695B2 (en) | 2013-03-14 | 2015-10-13 | Medtronic, Inc. | Injectable ropinirole compositions and methods for making and using same |
EP3640240B1 (fr) | 2017-06-16 | 2020-12-09 | Zhejiang Huahai Licheng Pharmaceutical Co., Ltd. | Procédé de purification de chlorhydrate de ropinirole |
CN115466209A (zh) * | 2022-09-29 | 2022-12-13 | 南通大学 | 一种罗匹尼罗环戊烷并吲哚酮杂质的合成方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA895875A (en) * | 1972-03-21 | Bourdais Jacques | Mercapto indole derivatives | |
US3573310A (en) * | 1967-09-28 | 1971-03-30 | Miles Lab | 1-substituted derivatives of 2-indolinone |
JPS5825673B2 (ja) * | 1976-03-31 | 1983-05-28 | 大塚製薬株式会社 | オキシインド−ル誘導体 |
JPS5840539B2 (ja) * | 1976-03-31 | 1983-09-06 | 大塚製薬株式会社 | α−置換アミノアルカノイルオキシインド−ル誘導体 |
JPS5919537B2 (ja) * | 1976-08-02 | 1984-05-07 | 大塚製薬株式会社 | オキシインド−ル誘導体 |
US4317944A (en) * | 1980-08-15 | 1982-03-02 | General Electric Company | Preparation of 2,2-bis(4-hydroxyphenyl) propane |
US4314944A (en) * | 1980-08-22 | 1982-02-09 | Smithkline Corporation | 4-Aminoalkyl-7-hydroxy-2(3H)-indolones |
-
1982
- 1982-12-07 US US06/447,564 patent/US4452808A/en not_active Expired - Lifetime
-
1983
- 1983-11-17 CA CA000441416A patent/CA1208650A/fr not_active Expired
- 1983-11-21 NZ NZ206344A patent/NZ206344A/en unknown
- 1983-11-22 AU AU21585/83A patent/AU560170B2/en not_active Expired
- 1983-11-23 IL IL70311A patent/IL70311A/xx not_active IP Right Cessation
- 1983-11-25 PT PT77739A patent/PT77739B/pt unknown
- 1983-11-25 ZW ZW258/83A patent/ZW25883A1/xx unknown
- 1983-11-28 PH PH29901A patent/PH22067A/en unknown
- 1983-11-30 DE DE8383307289T patent/DE3367090D1/de not_active Expired
- 1983-11-30 LU LU90097C patent/LU90097I2/fr unknown
- 1983-11-30 EP EP83307289A patent/EP0113964B1/fr not_active Expired
- 1983-11-30 CY CY1497A patent/CY1497A/xx unknown
- 1983-12-02 FI FI834421A patent/FI77849C/fi not_active IP Right Cessation
- 1983-12-05 GR GR73156A patent/GR79121B/el unknown
- 1983-12-05 EG EG753/83A patent/EG16556A/xx active
- 1983-12-06 IE IE2866/83A patent/IE56347B1/en not_active IP Right Cessation
- 1983-12-06 JP JP58231215A patent/JPS59112964A/ja active Granted
- 1983-12-06 DK DK562183A patent/DK156514C/da not_active IP Right Cessation
- 1983-12-06 ES ES527827A patent/ES8600239A1/es not_active Expired
- 1983-12-06 NO NO834485A patent/NO160135C/no unknown
- 1983-12-07 ZA ZA839094A patent/ZA839094B/xx unknown
- 1983-12-07 KR KR1019830005790A patent/KR910001042B1/ko not_active IP Right Cessation
-
1984
- 1984-12-07 DZ DZ847014A patent/DZ587A1/fr active
-
1985
- 1985-05-29 ES ES543593A patent/ES8604143A1/es not_active Expired
-
1989
- 1989-10-12 HK HK820/89A patent/HK82089A/xx not_active IP Right Cessation
-
1991
- 1991-12-20 CZ CS913981A patent/CZ398191A3/cs unknown
-
1996
- 1996-08-30 BR BR1100036-8A patent/BR1100036A/pt active IP Right Grant
-
1997
- 1997-02-05 NL NL970005C patent/NL970005I2/nl unknown
-
1999
- 1999-06-18 NO NO1999011C patent/NO1999011I1/no unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DZ587A1 (fr) | 4-Aminoalkyl-2(3H) inolones. | |
FI78601B (fi) | Engaongsbloeja. | |
FI78611B (fi) | Uppbevaringspaose. | |
FI73534B (fi) | Bandkassett. | |
FI73505B (fi) | Faestelement. | |
FI842543A (fi) | Transportlaoda. | |
NO831596L (no) | Roerlednings-stoette. | |
FI77050B (fi) | Gelatinkomposition foer sprutgjutning. | |
FI78606B (fi) | Saekerhetssaete. | |
DE3381054D1 (de) | Immunoessay. | |
FI834178A (fi) | Avsaendar- och mottagarantenner. | |
FI834433A (fi) | Svaenghjulskraftoeverfoering. | |
FI73520B (fi) | Maolanordning. | |
FI842060A0 (fi) | Foerstaerkarkoppling. | |
FI834725A (fi) | Tryckmediepaoverkad gripanordning. | |
DE3382498D1 (de) | Konservenbuechse. | |
ES272075Y (es) | Corretilla. | |
FI841618A0 (fi) | Foer rostbehandling avsedda kompositioner. | |
FI841575A (fi) | Tangentmekanism. | |
NO163198C (no) | Foringsroer-innrettingsverktoey. | |
FI834357A (fi) | Dragfordon. | |
FI843194A (fi) | Verkningsanordning. | |
MX9203742A (es) | 4-aminoalquil-2(3h)-indolonas. | |
FI73929B (fi) | Foerflyttbar lasttransportoer. | |
NO820446L (no) | Vaeskedoseringsanordning. |