DZ3007A1 - Analogues de (1 R, CIS)-4-(6-amino-9H-purin-9-YL)-2-cyclopentène-1-methanol comme agents antiviraux. - Google Patents

Analogues de (1 R, CIS)-4-(6-amino-9H-purin-9-YL)-2-cyclopentène-1-methanol comme agents antiviraux.

Info

Publication number
DZ3007A1
DZ3007A1 DZ000019A DZ000019A DZ3007A1 DZ 3007 A1 DZ3007 A1 DZ 3007A1 DZ 000019 A DZ000019 A DZ 000019A DZ 000019 A DZ000019 A DZ 000019A DZ 3007 A1 DZ3007 A1 DZ 3007A1
Authority
DZ
Algeria
Prior art keywords
purin
cyclopentene
analogs
cis
methanol
Prior art date
Application number
DZ000019A
Other languages
English (en)
French (fr)
Inventor
Susan Mary Daluge
Christopher Mcguigan
Original Assignee
Glaxo Group Ltd
Gbuniversity College Cardiff C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9903090.0A external-priority patent/GB9903090D0/en
Application filed by Glaxo Group Ltd, Gbuniversity College Cardiff C filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DZ3007A1 publication Critical patent/DZ3007A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
DZ000019A 1999-02-12 2000-03-09 Analogues de (1 R, CIS)-4-(6-amino-9H-purin-9-YL)-2-cyclopentène-1-methanol comme agents antiviraux. DZ3007A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9903090.0A GB9903090D0 (en) 1999-02-12 1999-02-12 Therapeutic compounds
US17020599P 1999-12-10 1999-12-10

Publications (1)

Publication Number Publication Date
DZ3007A1 true DZ3007A1 (fr) 2003-03-27

Family

ID=26315118

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ000019A DZ3007A1 (fr) 1999-02-12 2000-03-09 Analogues de (1 R, CIS)-4-(6-amino-9H-purin-9-YL)-2-cyclopentène-1-methanol comme agents antiviraux.

Country Status (24)

Country Link
US (1) US7115590B1 (xx)
EP (1) EP1150988B1 (xx)
JP (1) JP2002536452A (xx)
KR (1) KR20010102082A (xx)
CN (1) CN1346360A (xx)
AR (1) AR031975A1 (xx)
AT (1) ATE241633T1 (xx)
AU (1) AU772478B2 (xx)
BR (1) BR0008135A (xx)
CA (1) CA2362662A1 (xx)
CZ (1) CZ20012908A3 (xx)
DE (1) DE60002986T2 (xx)
DK (1) DK1150988T3 (xx)
DZ (1) DZ3007A1 (xx)
ES (1) ES2200820T3 (xx)
HK (1) HK1039337B (xx)
HU (1) HUP0105476A3 (xx)
IL (1) IL144647A0 (xx)
NO (1) NO20013910L (xx)
NZ (1) NZ513450A (xx)
PL (1) PL204458B1 (xx)
PT (1) PT1150988E (xx)
TR (1) TR200102313T2 (xx)
WO (1) WO2000047591A1 (xx)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001042255A1 (en) * 1999-12-10 2001-06-14 Glaxo Group Limited (1R,CIS)-4-(4-AMINO-7H-PYRROLO'2,3-I(D) ! PYRIMIDINE-7-YL)-2-CYCLOPENTENE-1-METHANOL DERIVATIVES AS ANTIVIRAL
PE20010915A1 (es) * 1999-12-10 2001-09-29 Glaxo Group Ltd Analogos de (1s, cis)-4-(2-amino-9h-purin-9-il)-2-ciclopenten-1-metanol para uso en el tratamiento de infecciones virales
EA200601591A1 (ru) 2000-05-26 2007-02-27 Айденикс (Кайман) Лимитед Применение рибонуклеозидных соединений для лечения флавивирусных и пестивирусных инфекций
HRP20160074B1 (hr) † 2000-07-21 2021-09-03 Gilead Sciences, Inc. Prolijekovi koji su fosfonatni analozi nukleotida i metode njihovog odabira te njihova priprava
GB0129945D0 (en) * 2001-12-13 2002-02-06 Mrc Technology Ltd Chemical compounds
GB0401088D0 (en) 2004-01-19 2004-02-18 Univ Cardiff Phosphoramidate derivatives
EP2691409B1 (en) 2011-03-31 2018-02-21 Idenix Pharmaceuticals LLC. Compounds and pharmaceutical compositions for the treatment of viral infections
EP2755983B1 (en) 2011-09-12 2017-03-15 Idenix Pharmaceuticals LLC. Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
US8507460B2 (en) 2011-10-14 2013-08-13 Idenix Pharmaceuticals, Inc. Substituted 3′,5′-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
US9296778B2 (en) 2012-05-22 2016-03-29 Idenix Pharmaceuticals, Inc. 3′,5′-cyclic phosphate prodrugs for HCV infection
AU2013266393B2 (en) 2012-05-22 2017-09-28 Idenix Pharmaceuticals Llc D-amino acid compounds for liver disease
EP2852604B1 (en) 2012-05-22 2017-04-12 Idenix Pharmaceuticals LLC 3',5'-cyclic phosphoramidate prodrugs for hcv infection
EA027929B1 (ru) 2012-05-25 2017-09-29 Янссен Сайенсиз Айрлэнд Юси Нуклеозиды на основе урацила и спирооксетана
WO2014052638A1 (en) 2012-09-27 2014-04-03 Idenix Pharmaceuticals, Inc. Esters and malonates of sate prodrugs
ES2674980T3 (es) 2012-10-08 2018-07-05 Idenix Pharmaceuticals Llc Análogos de 2'-cloro nucleósidos para infección por VHC
US10723754B2 (en) 2012-10-22 2020-07-28 Idenix Pharmaceuticals Llc 2′,4′-bridged nucleosides for HCV infection
EP2935304A1 (en) 2012-12-19 2015-10-28 IDENIX Pharmaceuticals, Inc. 4'-fluoro nucleosides for the treatment of hcv
US9309275B2 (en) 2013-03-04 2016-04-12 Idenix Pharmaceuticals Llc 3′-deoxy nucleosides for the treatment of HCV
US9339541B2 (en) 2013-03-04 2016-05-17 Merck Sharp & Dohme Corp. Thiophosphate nucleosides for the treatment of HCV
EP2970357A1 (en) 2013-03-13 2016-01-20 IDENIX Pharmaceuticals, Inc. Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv
WO2014165542A1 (en) 2013-04-01 2014-10-09 Idenix Pharmaceuticals, Inc. 2',4'-fluoro nucleosides for the treatment of hcv
US10005779B2 (en) 2013-06-05 2018-06-26 Idenix Pharmaceuticals Llc 1′,4′-thio nucleosides for the treatment of HCV
EP3027636B1 (en) 2013-08-01 2022-01-05 Idenix Pharmaceuticals LLC D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
WO2015161137A1 (en) 2014-04-16 2015-10-22 Idenix Pharmaceuticals, Inc. 3'-substituted methyl or alkynyl nucleosides for the treatment of hcv
LU100724B1 (en) 2016-07-14 2018-07-31 Atea Pharmaceuticals Inc Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
EP3865136A1 (en) 2016-09-07 2021-08-18 ATEA Pharmaceuticals, Inc. 2'-substituted-n6-substituted purine nucleotides for corona virus treatment
WO2021173713A1 (en) 2020-02-27 2021-09-02 Atea Pharmaceuticals, Inc. Highly active compounds against covid-19
US10874687B1 (en) 2020-02-27 2020-12-29 Atea Pharmaceuticals, Inc. Highly active compounds against COVID-19

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244896A (en) * 1990-09-14 1993-09-14 Marion Merrell Dow Inc. Carbocyclic adenosine analogs useful as immunosuppressants
GB9505025D0 (en) * 1995-03-13 1995-05-03 Medical Res Council Chemical compounds
US6887707B2 (en) * 1996-10-28 2005-05-03 University Of Washington Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA
GB9821058D0 (en) * 1998-09-28 1998-11-18 Univ Cardiff Chemical compound
WO2001042255A1 (en) * 1999-12-10 2001-06-14 Glaxo Group Limited (1R,CIS)-4-(4-AMINO-7H-PYRROLO'2,3-I(D) ! PYRIMIDINE-7-YL)-2-CYCLOPENTENE-1-METHANOL DERIVATIVES AS ANTIVIRAL
US20030096833A1 (en) * 2001-08-31 2003-05-22 Jagtap Prakash G. Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof

Also Published As

Publication number Publication date
US7115590B1 (en) 2006-10-03
AR031975A1 (es) 2003-10-22
ES2200820T3 (es) 2004-03-16
WO2000047591A1 (en) 2000-08-17
EP1150988B1 (en) 2003-05-28
NO20013910L (no) 2001-10-10
PL204458B1 (pl) 2010-01-29
IL144647A0 (en) 2002-05-23
KR20010102082A (ko) 2001-11-15
HK1039337A1 (en) 2002-04-19
HUP0105476A2 (en) 2002-06-29
NZ513450A (en) 2004-03-26
DK1150988T3 (da) 2003-09-29
ATE241633T1 (de) 2003-06-15
AU2671300A (en) 2000-08-29
PL350023A1 (en) 2002-10-21
NO20013910D0 (no) 2001-08-10
TR200102313T2 (tr) 2002-03-21
CA2362662A1 (en) 2000-08-17
DE60002986D1 (en) 2003-07-03
CZ20012908A3 (cs) 2002-10-16
BR0008135A (pt) 2002-02-19
AU772478B2 (en) 2004-04-29
DE60002986T2 (de) 2004-05-19
CN1346360A (zh) 2002-04-24
HUP0105476A3 (en) 2002-08-28
JP2002536452A (ja) 2002-10-29
EP1150988A1 (en) 2001-11-07
PT1150988E (pt) 2003-10-31
HK1039337B (zh) 2003-11-21

Similar Documents

Publication Publication Date Title
DZ3007A1 (fr) Analogues de (1 R, CIS)-4-(6-amino-9H-purin-9-YL)-2-cyclopentène-1-methanol comme agents antiviraux.
PT1225874E (pt) Composicoes antivirais.
FR12C0041I2 (fr) Analogues de somatostatine
WO1999064047A8 (en) Novel antiviral compounds
GC0000174A (en) Nucleoside analogues suitable for use as anti-viral agents
DE69920035D1 (de) Hochkonzentrierte wässrige glyphosatzusammensetzungen
AP2002002529A0 (en) 2,4-Diaminopyrimidine compounds useful as immunosupressants
HK1041699A1 (zh) 作為抗病毒劑的喹啉羧酰胺
AP2003002932A0 (en) Thiophene derivatives as antiviral agents for flavviirus infection.
EE200200275A (et) Immunosupressantidena kasutatavad 2,4-diaminopürimidiiniühendid
FR05C0032I2 (fr) Analogues de nucleotides
MXPA03007595A (es) Analogos de acido ascorbico para metalorradiofarmaceuticos.
GB0128526D0 (en) Nucleotide analogues
ZA976242B (en) Illudin analogs useful as antitumor agents.
MXPA03000107A (es) Pirroloquinolonas como agentes antivirales.
EG23909A (en) Vatamin d, analogs
AU6807501A (en) 1-aryl-4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents
AU7810098A (en) 9-oxa prostaglandin analogs as ocular hypotensives
ATE377068T1 (de) Tensidzusammensetzungen, verbesserungsmittel enthaltend
EP1568704A4 (en) NOVEL 2 ', 5'-OLIGOADENIC ACID ANALOG
HK1054037A1 (zh) 作為抗病毒劑的4-羥基-1，8-二氮雜萘-3-羧酰胺
HK1051179A1 (en) Prostaglandin e analogues.
PL366978A1 (en) Hydroxyfattysulfonic acid analogs
GC0000195A (en) Benzoamido- and thiophenecarboxyamido-1,2,3,4-tetrahydroisoquinol-7-ine compunds as anticonvulsant agents
AU2068901A (en) Analogs of (1s, cis)-4-(2-amino-9h-purin-9-yl)-2-cyclopentene-1-methanol as antiviral