DZ2141A1 - Procédés intermédiares pour la préparation de 1-benzyl-4-(5,6-diméthoxy-1-indanone)-2-yi)méthylpipéridine. - Google Patents

Procédés intermédiares pour la préparation de 1-benzyl-4-(5,6-diméthoxy-1-indanone)-2-yi)méthylpipéridine.

Info

Publication number
DZ2141A1
DZ2141A1 DZ960186A DZ960186A DZ2141A1 DZ 2141 A1 DZ2141 A1 DZ 2141A1 DZ 960186 A DZ960186 A DZ 960186A DZ 960186 A DZ960186 A DZ 960186A DZ 2141 A1 DZ2141 A1 DZ 2141A1
Authority
DZ
Algeria
Prior art keywords
indanone
methylpiperidine
dimethoxy
benzyl
preparation
Prior art date
Application number
DZ960186A
Other languages
English (en)
French (fr)
Inventor
Keith M Devries
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DZ2141A1 publication Critical patent/DZ2141A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DZ960186A 1995-12-15 1996-12-11 Procédés intermédiares pour la préparation de 1-benzyl-4-(5,6-diméthoxy-1-indanone)-2-yi)méthylpipéridine. DZ2141A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US875395P 1995-12-15 1995-12-15

Publications (1)

Publication Number Publication Date
DZ2141A1 true DZ2141A1 (fr) 2002-07-23

Family

ID=21733469

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ960186A DZ2141A1 (fr) 1995-12-15 1996-12-11 Procédés intermédiares pour la préparation de 1-benzyl-4-(5,6-diméthoxy-1-indanone)-2-yi)méthylpipéridine.

Country Status (33)

Country Link
EP (1) EP0883607A1 (zh)
JP (1) JP3066083B2 (zh)
KR (1) KR20000064387A (zh)
AP (1) AP708A (zh)
AR (1) AR004368A1 (zh)
AU (1) AU716462B2 (zh)
BG (1) BG102525A (zh)
BR (1) BR9612018A (zh)
CA (1) CA2237647A1 (zh)
CO (1) CO4750831A1 (zh)
CZ (1) CZ180898A3 (zh)
DZ (1) DZ2141A1 (zh)
GT (1) GT199600092A (zh)
HN (1) HN1996000065A (zh)
HR (1) HRP960592A2 (zh)
HU (1) HUP9904275A3 (zh)
IL (3) IL136421A0 (zh)
IS (1) IS4752A (zh)
MA (1) MA24032A1 (zh)
NO (1) NO982712L (zh)
NZ (1) NZ318843A (zh)
OA (1) OA10694A (zh)
PE (1) PE25698A1 (zh)
PL (1) PL197306B1 (zh)
RO (1) RO121382B1 (zh)
RU (1) RU2160731C2 (zh)
SK (1) SK75498A3 (zh)
TN (1) TNSN96153A1 (zh)
TW (1) TW414787B (zh)
UY (1) UY24401A1 (zh)
WO (1) WO1997022584A1 (zh)
YU (1) YU49486B (zh)
ZA (1) ZA9610533B (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1047674B1 (en) 1998-01-16 2005-03-30 Eisai Co., Ltd. Process for production of donepezil derivatives
IL125809A (en) 1998-08-17 2005-08-31 Finetech Lab Ltd Process and intermediates for production of donepezil and related compounds
US7148354B2 (en) * 2002-07-24 2006-12-12 Dr. Reddy's Laboratories Limited Process for preparation of donepezil
IL150982A (en) 2002-07-30 2007-02-11 Ori Lerman Process for making Donafzil
IL151253A0 (en) * 2002-08-14 2003-04-10 Finetech Lab Ltd Process for production of highly pure donepezil hydrochloride
US6953856B2 (en) 2003-02-12 2005-10-11 Usv, Limited Process for the preparation of 1-benzyl-4-(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCI)
US6649765B1 (en) 2003-02-12 2003-11-18 Usv Limited, Bsd Marg. Process for the preparation of 1-benzyl-4(5,6-dimethoxy-1-indanon)-2-yl) methyl piperidine hydrochloride (Donepezil HCL)
WO2004082685A1 (en) * 2003-03-21 2004-09-30 Ranbaxy Laboratories Limited Process for the preparation of donepezil and derivatives thereof
WO2004099142A1 (en) * 2003-05-05 2004-11-18 Ranbaxy Laboratories Limited Hydrobromide salt of benzyl-piperidylmethyl-indanone and its polymorphs
AU2003247158A1 (en) 2003-07-01 2005-01-21 Hetero Drugs Limited Preparation of intermediates for acetyl cholinesterase inhibitors
CN1280273C (zh) * 2003-11-05 2006-10-18 天津和美生物技术有限公司 合成多奈哌齐及其衍生物的方法
CA2581926A1 (en) 2004-09-29 2006-04-06 Chemagis Ltd. Use of purified donepezil maleate for preparing pharmaceutically pure amorphous donepezil hydrochloride
CN100436416C (zh) * 2005-07-29 2008-11-26 西南合成制药股份有限公司 盐酸多奈哌齐合成工艺
GB0515803D0 (en) * 2005-07-30 2005-09-07 Pliva Hrvatska D O O Intermediate compounds
AR057910A1 (es) 2005-11-18 2007-12-26 Synthon Bv Proceso para preparar donepezilo
EP1973878B1 (en) 2006-01-04 2010-11-24 Cipla Limited Process and intermediate for preparation of donepezil
CN101626688A (zh) * 2006-12-11 2010-01-13 雷维瓦药品公司 茚满酮基胆碱酯酶抑制剂的组合物、合成和使用方法
WO2013078608A1 (en) 2011-11-29 2013-06-06 Ziqiang Gu Donepezil pamoate and methods of making and using the same
EP3033082B1 (en) 2013-08-16 2021-06-16 Universiteit Maastricht Treatment of cognitive impairment with pde4 inhibitor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
FR2642069B1 (fr) * 1989-01-20 1991-04-12 Rhone Poulenc Sante Nouveaux derives du benzopyranne, leur preparation et les compositions pharmaceutiques qui les contiennent
DE4439822A1 (de) * 1994-11-08 1996-08-29 Bayer Ag Verfahren zur Herstellung von Benzyl-piperidylmethyl-indanonen

Also Published As

Publication number Publication date
AU7092596A (en) 1997-07-14
PL327512A1 (en) 1998-12-21
CO4750831A1 (es) 1999-03-31
BG102525A (en) 1999-05-31
AP9600892A0 (en) 1997-01-31
TNSN96153A1 (fr) 2005-03-15
KR20000064387A (ko) 2000-11-06
IS4752A (is) 1998-05-22
UY24401A1 (es) 1997-06-09
CA2237647A1 (en) 1997-06-26
RO121382B1 (ro) 2007-04-30
EP0883607A1 (en) 1998-12-16
AP708A (en) 1998-12-04
MA24032A1 (fr) 1997-07-01
YU49486B (sh) 2006-08-17
AU716462B2 (en) 2000-02-24
GT199600092A (es) 1998-05-12
PL197306B1 (pl) 2008-03-31
RU2160731C2 (ru) 2000-12-20
MX9804820A (es) 1998-10-31
AR004368A1 (es) 1998-11-04
JP3066083B2 (ja) 2000-07-17
SK75498A3 (en) 1999-08-06
HUP9904275A3 (en) 2001-05-28
NO982712D0 (no) 1998-06-12
PE25698A1 (es) 1998-05-21
HUP9904275A2 (hu) 2000-05-28
CZ180898A3 (cs) 1999-05-12
TW414787B (en) 2000-12-11
JPH11500756A (ja) 1999-01-19
YU66096A (en) 1999-11-22
IL124452A0 (en) 1998-12-06
IL136421A0 (en) 2001-06-14
HN1996000065A (es) 1997-06-26
BR9612018A (pt) 1999-02-17
WO1997022584A1 (en) 1997-06-26
IL136420A0 (en) 2001-06-14
HRP960592A2 (en) 1998-06-30
NO982712L (no) 1998-06-12
NZ318843A (en) 2000-01-28
ZA9610533B (en) 1998-06-15
OA10694A (en) 2001-05-04

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