DOP2005000259A - Compuesto químico y su uso. - Google Patents
Compuesto químico y su uso.Info
- Publication number
- DOP2005000259A DOP2005000259A DO2005P000259A DO2005000259A DOP2005000259A DO P2005000259 A DOP2005000259 A DO P2005000259A DO 2005P000259 A DO2005P000259 A DO 2005P000259A DO 2005000259 A DO2005000259 A DO 2005000259A DO P2005000259 A DOP2005000259 A DO P2005000259A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- chemical compound
- prevention
- preparation
- treatment
- diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Quinoline Compounds (AREA)
Abstract
LA PRESENTE SOLICITUD SE REFIERE A UN NUEVO DERIVADO DE TETRAHIDROQUINOLINA, A UN PROCEDIMIENTO PARA SU PREPARACION, A SU USO SOLO O EN COMBINACIONES PARA EL TRATAMIENTO Y/O LA PREVENCION DE ENFERMEDADES, ASI COMO A SU USO PARA LA PREPARACIÓN DE FARMACOS, ESPECIALMENTE COMO INHIBIDOR DE LA PROTEINA DE TRANSFERENCIA DE ESTER DE COLESTEROL (CETP) PARA EL TRATAMIENTO Y/O LA PREVENCION DE ENFERMEDADES CARDIOVASCULARES, ESPECIALMENTE DE HIPOLIPOPROTEINEMIAS, DISLIPIDEMIAS, HIPERTRIGLICERIDEMIAS, HIPERLIPIDEMIAS, HIPERCOLESTEROLEMIAS Y ARTERIOSCLEROSIS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004060997A DE102004060997A1 (de) | 2004-12-18 | 2004-12-18 | Chemische Verbindung und ihre Verwendung |
DE102004061000A DE102004061000A1 (de) | 2004-12-18 | 2004-12-18 | Chemische Verbindung und ihre Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
DOP2005000259A true DOP2005000259A (es) | 2006-11-15 |
Family
ID=35841894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DO2005P000259A DOP2005000259A (es) | 2004-12-18 | 2005-12-16 | Compuesto químico y su uso. |
Country Status (27)
Country | Link |
---|---|
US (2) | US8124775B2 (es) |
EP (1) | EP1828137B1 (es) |
JP (1) | JP5132317B2 (es) |
KR (1) | KR20070090248A (es) |
AR (1) | AR055011A1 (es) |
AT (1) | ATE555097T1 (es) |
AU (1) | AU2005315770B2 (es) |
BR (1) | BRPI0519602A2 (es) |
CA (1) | CA2591397A1 (es) |
CU (1) | CU23452B7 (es) |
CY (1) | CY1112887T1 (es) |
DK (1) | DK1828137T3 (es) |
DO (1) | DOP2005000259A (es) |
ES (1) | ES2384980T3 (es) |
GT (1) | GT200500377A (es) |
IL (1) | IL184008A (es) |
MA (1) | MA29100B1 (es) |
MX (1) | MX2007007188A (es) |
NO (1) | NO20073146L (es) |
PE (1) | PE20060767A1 (es) |
PL (1) | PL1828137T3 (es) |
PT (1) | PT1828137E (es) |
RU (1) | RU2393151C2 (es) |
SI (1) | SI1828137T1 (es) |
TW (1) | TW200635900A (es) |
UY (1) | UY29276A1 (es) |
WO (1) | WO2006063828A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2007007187A (es) * | 2004-12-18 | 2007-08-14 | Bayer Healthcare Ag | Derivados de (5s)-3-[(s)-fluoro-(4-trifluorometilfenil)metil]-5,6, 7,8-tetrahidroquinolin-5-ol y su uso como inhibidores de la proteina de transferencia de ester de colesterol. |
DE102006012548A1 (de) * | 2006-03-18 | 2007-09-20 | Bayer Healthcare Ag | Substituierte Chromanol-Derivate und ihre Verwendung |
PL2268644T3 (pl) * | 2008-03-05 | 2012-01-31 | Boehringer Ingelheim Int | Tricykliczne pochodne piperydyny, leki zawierające te związki, ich zastosowanie i sposoby ich wytwarzania |
JP5780528B2 (ja) | 2010-02-19 | 2015-09-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 三環式ピリジン誘導体、このような化合物を含有する医薬、それらの使用、およびそれらの調製方法 |
RU2572606C2 (ru) * | 2010-07-09 | 2016-01-20 | Дайити Санкио Компани, Лимитед | Замещенное пиридиновое соединение |
US20130053404A1 (en) | 2011-02-17 | 2013-02-28 | Boehringer Ingelheim International Gmbh | Tricyclic pyridine derivatives, medicaments containing such compounds, their use and process for their preparation |
AR087577A1 (es) | 2011-08-17 | 2014-04-03 | Boehringer Ingelheim Int | Derivados de furo[3,4-c]quinolina, medicamentos que contienen dichos compuestos, su uso y proceso para su preparacion |
ES2599757T3 (es) | 2012-01-06 | 2017-02-03 | Daiichi Sankyo Company, Limited | Sales de aducto de ácido de un compuesto de piridina sustituido como inhibidores de la proteína de transferencia de ésteres de colesterilo (PTEC) |
KR102456013B1 (ko) | 2014-07-30 | 2022-10-18 | 에프. 호프만-라 로슈 아게 | 고밀도 지질단백질(hdl)-상승 제제 또는 hdl-모방 제제에 의한 치료법에 대한 반응성을 예측하기 위한 유전 표지 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19610932A1 (de) | 1996-03-20 | 1997-09-25 | Bayer Ag | 2-Aryl-substituierte Pyridine |
DE19627431A1 (de) | 1996-07-08 | 1998-01-15 | Bayer Ag | Heterocyclisch kondensierte Pyridine |
HRP970330B1 (en) * | 1996-07-08 | 2004-06-30 | Bayer Ag | Cycloalkano pyridines |
US6207671B1 (en) | 1996-07-08 | 2001-03-27 | Bayer Aktiengesellschaft | Cycloalkano-pyridines |
DE19627430A1 (de) | 1996-07-08 | 1998-01-15 | Bayer Ag | Bicyclisch kondensierte Pyridine |
DE19704244A1 (de) | 1997-02-05 | 1998-08-06 | Bayer Ag | 5-Hydroxy-alkyl substituierte Phenyle |
DE19709125A1 (de) | 1997-03-06 | 1998-09-10 | Bayer Ag | Substituierte Chinoline |
DE19741051A1 (de) * | 1997-09-18 | 1999-03-25 | Bayer Ag | Hetero-Tetrahydrochinoline |
MA24643A1 (fr) * | 1997-09-18 | 1999-04-01 | Bayer Ag | Tetrahydro-naphtalenes substitues et composes analogues |
DE19741399A1 (de) * | 1997-09-19 | 1999-03-25 | Bayer Ag | Tetrahydrochinoline |
DE19935966A1 (de) | 1999-07-30 | 2001-02-01 | Bayer Ag | Verfahren zur Reduktion von Ketoalkoholen |
DE10148436A1 (de) | 2001-10-01 | 2003-04-17 | Bayer Ag | Tetrahydrochinoline |
DE10250687A1 (de) | 2002-10-31 | 2004-05-13 | Bayer Ag | 7H-Dibenzo(b,g)(1,5)dioxocin-5-on-Derivate und ihre Verwendung |
MX2007007187A (es) * | 2004-12-18 | 2007-08-14 | Bayer Healthcare Ag | Derivados de (5s)-3-[(s)-fluoro-(4-trifluorometilfenil)metil]-5,6, 7,8-tetrahidroquinolin-5-ol y su uso como inhibidores de la proteina de transferencia de ester de colesterol. |
-
2005
- 2005-12-15 AT AT05820528T patent/ATE555097T1/de active
- 2005-12-15 EP EP05820528A patent/EP1828137B1/de not_active Not-in-force
- 2005-12-15 AU AU2005315770A patent/AU2005315770B2/en not_active Ceased
- 2005-12-15 JP JP2007545948A patent/JP5132317B2/ja not_active Expired - Fee Related
- 2005-12-15 DK DK05820528.7T patent/DK1828137T3/da active
- 2005-12-15 PT PT05820528T patent/PT1828137E/pt unknown
- 2005-12-15 RU RU2007127127/04A patent/RU2393151C2/ru not_active IP Right Cessation
- 2005-12-15 KR KR1020077016219A patent/KR20070090248A/ko not_active Application Discontinuation
- 2005-12-15 US US11/793,482 patent/US8124775B2/en not_active Expired - Fee Related
- 2005-12-15 ES ES05820528T patent/ES2384980T3/es active Active
- 2005-12-15 BR BRPI0519602-7A patent/BRPI0519602A2/pt not_active IP Right Cessation
- 2005-12-15 PL PL05820528T patent/PL1828137T3/pl unknown
- 2005-12-15 MX MX2007007188A patent/MX2007007188A/es active IP Right Grant
- 2005-12-15 CA CA002591397A patent/CA2591397A1/en not_active Abandoned
- 2005-12-15 WO PCT/EP2005/013490 patent/WO2006063828A1/de active Application Filing
- 2005-12-15 SI SI200531547T patent/SI1828137T1/sl unknown
- 2005-12-16 DO DO2005P000259A patent/DOP2005000259A/es unknown
- 2005-12-16 PE PE2005001475A patent/PE20060767A1/es not_active Application Discontinuation
- 2005-12-16 TW TW094144588A patent/TW200635900A/zh unknown
- 2005-12-16 AR ARP050105313A patent/AR055011A1/es not_active Application Discontinuation
- 2005-12-19 GT GT200500377A patent/GT200500377A/es unknown
- 2005-12-20 UY UY29276A patent/UY29276A1/es not_active Application Discontinuation
-
2007
- 2007-06-18 MA MA30003A patent/MA29100B1/fr unknown
- 2007-06-18 CU CU20070140A patent/CU23452B7/es not_active IP Right Cessation
- 2007-06-18 IL IL184008A patent/IL184008A/en not_active IP Right Cessation
- 2007-06-19 NO NO20073146A patent/NO20073146L/no not_active Application Discontinuation
-
2012
- 2012-02-16 US US13/398,290 patent/US20120142728A1/en not_active Abandoned
- 2012-06-29 CY CY20121100588T patent/CY1112887T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
AR055011A1 (es) | 2007-08-01 |
US8124775B2 (en) | 2012-02-28 |
JP5132317B2 (ja) | 2013-01-30 |
ES2384980T3 (es) | 2012-07-16 |
CA2591397A1 (en) | 2006-06-22 |
AU2005315770A1 (en) | 2006-06-22 |
US20120142728A1 (en) | 2012-06-07 |
MX2007007188A (es) | 2007-08-14 |
CY1112887T1 (el) | 2016-04-13 |
RU2393151C2 (ru) | 2010-06-27 |
PE20060767A1 (es) | 2006-09-10 |
IL184008A0 (en) | 2007-10-31 |
EP1828137B1 (de) | 2012-04-25 |
EP1828137A1 (de) | 2007-09-05 |
GT200500377A (es) | 2006-11-09 |
UY29276A1 (es) | 2006-07-31 |
JP2008524145A (ja) | 2008-07-10 |
PL1828137T3 (pl) | 2012-09-28 |
SI1828137T1 (sl) | 2012-08-31 |
BRPI0519602A2 (pt) | 2009-02-25 |
IL184008A (en) | 2012-03-29 |
MA29100B1 (fr) | 2007-12-03 |
PT1828137E (pt) | 2012-07-04 |
AU2005315770B2 (en) | 2011-12-08 |
RU2007127127A (ru) | 2009-01-27 |
TW200635900A (en) | 2006-10-16 |
KR20070090248A (ko) | 2007-09-05 |
US20080255068A1 (en) | 2008-10-16 |
NO20073146L (no) | 2007-09-18 |
CU23452B7 (es) | 2009-12-01 |
WO2006063828A1 (de) | 2006-06-22 |
ATE555097T1 (de) | 2012-05-15 |
DK1828137T3 (da) | 2012-07-23 |
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